Routes of administration: Difference between revisions

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===Intravenous===

Intravenous administration refers to a drug being directly introduced into the bloodstream using a hypodermic needle. This method has the benefit of very short onset and eliminates absorption by directly entering the bloodstream, however much greater care must be taken when compared to other methods of administration. Sterilized, unused needles and a high purity substance with little to no adulterant is required to avoid damage to the circulatory system. Making sure no air bubbles are present in the reservoir before the plunger is released is also of dire importance, as air bubbles in the bloodstream can easily be lethal. This method is commonly used with substances such as Heroin, but can be employed with almost any pure substance.

Intravenous administration refers to a drug being directly introduced into the bloodstream using a hypodermic needle. This method has the benefit of very short onset and eliminates absorption by directly entering the bloodstream, however much greater care must be taken when compared to other methods of administration. Sterilized, unused needles and a high purity substance with little to no adulterant is required to avoid damage to the circulatory system. Making sure no air bubbles are present in the reservoir before the plunger is released is also of dire importance, as air bubbles in the bloodstream can easily be lethal. This method is commonly used with substances such as Heroin , but can be employed with almost any pure substance.

===Intramuscular===

Intramuscular administration refers to a drug being injected into the muscle tissue using a hypodermic needle.

Intramuscular administration refers to a drug being injected into the muscle tissue using a hypodermic needle. This method is very similar to intravenous but is often more painful, and onset and absorption is decreased. Some drugs such as Ketamine require IM administration. Like intravenous administration, intramuscular injection must be taken with precaution, using sterilized unused needles and not leaving any residual air bubbles in the reservoir.

===Rectal/Plugging===

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 ===Intravenous===
-Intravenous administration refers to a drug being directly introduced into the bloodstream using a hypodermic needle. This method has the benefit of very short onset and eliminates absorption by directly entering the bloodstream, however much greater care must be taken when compared to other methods of administration. Sterilized, unused needles and a high purity substance with little to no adulterant is required to avoid damage to the circulatory system. Making sure no air bubbles are present in the reservoir before the plunger is released is also of dire importance, as air bubbles in the bloodstream can easily be lethal. This method is commonly used with substances such as Heroin, but can be employed with almost any pure substance.
+Intravenous administration refers to a drug being directly introduced into the bloodstream using a hypodermic needle. This method has the benefit of very short onset and eliminates absorption by directly entering the bloodstream, however much greater care must be taken when compared to other methods of administration. Sterilized, unused needles and a high purity substance with little to no adulterant is required to avoid damage to the circulatory system. Making sure no air bubbles are present in the reservoir before the plunger is released is also of dire importance, as air bubbles in the bloodstream can easily be lethal. This method is commonly used with substances such as Heroin , but can be employed with almost any pure substance.
 ===Intramuscular===
-Intramuscular administration refers to a drug being injected into the muscle tissue using a hypodermic needle.
+Intramuscular administration refers to a drug being injected into the muscle tissue using a hypodermic needle. This method is very similar to intravenous but is often more painful, and onset and absorption is decreased. Some drugs such as Ketamine require IM administration. Like intravenous administration, intramuscular injection must be taken with precaution, using sterilized unused needles and not leaving any residual air bubbles in the reservoir.
 ===Rectal/Plugging===