Pregabalin: Difference between revisions

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The most prominent of these cognitive effects generally include:

*'''[[Effect::Dizziness]]''' - The after effects are mostly positive with pregabalin, but dizziness can still be here, especially after doing a high dose.

*'''[[Effect::Anxiety suppression]]'''

*'''[[Effect::Analysis suppression]]'''

It suppresses lingering, recurrent thoughts of anxiety, which is presented as dizziness. It can paradoxically produce looming anxiety at doses slightly above minimally-effective dose. That's the subtle difference between Gabapentinoids and Benzos

* '''[[Effect::Empathy, affection, and sociability enhancement]]''' - Pregabalin presents distinct [[entactogen|entactogen/empathogenic]] effects. In contrast to [[benzodiazepines]] (which merely increase sociability through [[disinhibition]]), at high dosages pregabalin directly increases the urge to communicate with others with feelings of empathy, love, closeness and connection being well-defined. These effects, although weaker than that of [[MDMA]], are still prominent.

*'''[[Effect::Ego inflation]]'''

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*'''[[Effect::Suggestibility enhancement]]'''

*'''[[Effect::Amnesia]]''' - Compared to [[benzodiazepines]], pregabalin is only mildly amnesiac if not combined with other depressants. With chronic usage or high dosages, one should expect more "tip of the tongue" moments and impaired short-term memory (e.g., walking into a room and forgetting what you were supposed to do there). Total blackouts do not seem to occur except in combination with other substances.

*'''[[Effect::Anxiety suppression]]'''

*'''[[Effect::Emotion enhancement]]'''

*'''[[Effect::Cognitive euphoria]]'''<ref>{{cite book | date= 2012 | title=Abuse and Misuse Potential of Pregabalin: A Review of the Clinical Evidence | publisher=Canadian Agency for Drugs and Technologies in Health}}</ref> - Many users who take pregabalin describe a moderate to even intense euphoria, even at lower doses. Many users describe it as similar to [[opioid]] induced euphoria. The sensation itself can be described as powerful and overwhelming feelings of emotional bliss, contentment, and happiness.

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*'''[[Effect::Muscle relaxation]]''' - This effect is not as strong as the high but its still here in the afterglow.

*'''[[Effect::Motor control loss]]''' - This effect is weaker than the ''high'' but is still noticeable to the user. Driving while in the ''afterglow'' / comedown is a bad idea.

*'''[[Effect::Dizziness]]''' - The after effects are mostly positive with pregabalin, but dizziness can still be here, especially after doing a high dose.

}}

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*'''United Kingdom:''' The Misuse of Drugs Act 1971 makes it illegal to possess the drug without a prescription and, for such purposes, it is classified as a Class C drug.<ref>{{Citation | title=The Misuse of Drugs Act 1971 (Amendment) Order 2018 | url=https://www.legislation.gov.uk/uksi/2018/1356/article/2/made}}</ref>

*'''United States:''' Pregabalin is in Schedule V, indicating "low potential for abuse." For comparison, benzodiazepines are in Schedule IV.<ref>{{Citation | year=2016 | title=Title 21 CFR - PART 1308 - Section 1308.15 Schedule V | url=http://web.archive.org/web/20161017105621/https://www.deadiversion.usdoj.gov/21cfr/cfr/1308/1308_15.htm}}</ref>

<br />

== Combinations ==

with [[Memantine]] (anecdotal, N=1)<blockquote>Add-on of 20mg to 30mg Memantine per day to 75mg Pregabalin is equivalent to 300mg Pregabalin (I had tolerance of that much at the time. I have chronic anxiety)</blockquote>

==See also==

@@ Line 82: / Line 82: @@
 The most prominent of these cognitive effects generally include:
-*'''[[Effect::Dizziness]]''' - The after effects are mostly positive with pregabalin, but dizziness can still be here, especially after doing a high dose.
-*'''[[Effect::Anxiety suppression]]'''
 *'''[[Effect::Analysis suppression]]'''
-It suppresses lingering, recurrent thoughts of anxiety, which is presented as dizziness. It can paradoxically produce looming anxiety at doses slightly above minimally-effective dose.  That's the subtle difference between Gabapentinoids and Benzos
 * '''[[Effect::Empathy, affection, and sociability enhancement]]''' - Pregabalin presents distinct [[entactogen|entactogen/empathogenic]] effects. In contrast to [[benzodiazepines]] (which merely increase sociability through [[disinhibition]]), at high dosages pregabalin directly increases the urge to communicate with others with feelings of empathy, love, closeness and connection being well-defined. These effects, although weaker than that of [[MDMA]], are still prominent.
 *'''[[Effect::Ego inflation]]'''
@@ Line 91: / Line 88: @@
 *'''[[Effect::Suggestibility enhancement]]'''
 *'''[[Effect::Amnesia]]''' - Compared to [[benzodiazepines]], pregabalin is only mildly amnesiac if not combined with other depressants. With chronic usage or high dosages, one should expect more "tip of the tongue" moments and impaired short-term memory (e.g., walking into a room and forgetting what you were supposed to do there). Total blackouts do not seem to occur except in combination with other substances.
+*'''[[Effect::Anxiety suppression]]'''
 *'''[[Effect::Emotion enhancement]]'''
 *'''[[Effect::Cognitive euphoria]]'''<ref>{{cite book | date= 2012 | title=Abuse and Misuse Potential of Pregabalin: A Review of the Clinical Evidence | publisher=Canadian Agency for Drugs and Technologies in Health}}</ref> - Many users who take pregabalin describe a moderate to even intense euphoria, even at lower doses. Many users describe it as similar to [[opioid]] induced euphoria. The sensation itself can be described as powerful and overwhelming feelings of emotional bliss, contentment, and happiness.
@@ Line 119: / Line 116: @@
 *'''[[Effect::Muscle relaxation]]''' - This effect is not as strong as the high but its still here in the afterglow.
 *'''[[Effect::Motor control loss]]''' - This effect is weaker than the ''high'' but is still noticeable to the user. Driving while in the ''afterglow'' / comedown is a bad idea.
+*'''[[Effect::Dizziness]]''' - The after effects are mostly positive with pregabalin, but dizziness can still be here, especially after doing a high dose.
 }}
@@ Line 197: / Line 194: @@
 *'''United Kingdom:''' The Misuse of Drugs Act 1971 makes it illegal to possess the drug without a prescription and, for such purposes, it is classified as a Class C drug.<ref>{{Citation | title=The Misuse of Drugs Act 1971 (Amendment) Order 2018 | url=https://www.legislation.gov.uk/uksi/2018/1356/article/2/made}}</ref>
 *'''United States:''' Pregabalin is in Schedule V, indicating "low potential for abuse." For comparison, benzodiazepines are in Schedule IV.<ref>{{Citation | year=2016 | title=Title 21 CFR - PART 1308 - Section 1308.15 Schedule V | url=http://web.archive.org/web/20161017105621/https://www.deadiversion.usdoj.gov/21cfr/cfr/1308/1308_15.htm}}</ref>
+<br />
+== Combinations ==
+with [[Memantine]] (anecdotal, N=1)<blockquote>Add-on of 20mg to 30mg Memantine per day to 75mg Pregabalin is equivalent to 300mg Pregabalin (I had tolerance of that much at the time. I have chronic anxiety)</blockquote>
 ==See also==