Selective serotonin reuptake inhibitor: Difference between revisions

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SSRIs can be dangerous when used in combination with other substances that increase or modulate serotonin such as [[MDMA]] and [[MAOI|Monoamine Oxidase Inhibitors]] (MAOIs). A combination with these substances can lead to [[serotonin syndrome]] and potentially be fatal. SSRIs do not work for everyone and take 3-6 weeks to start having noticeable effects.<ref>{{Citation | year=2021 | title=Do Antidepressants Work Right Away? | url=https://psychcentral.com/depression/how-long-do-antidepressants-take-to-work}}</ref>

SSRIs are reported to have fewer side effects than older antidepressants like [[MAOI|monoamine oxidase inhibitors]] and [[tricyclic antidepressants]].{{citation needed}} [[MAOI|Monoamine oxidase inhibitors]] also interact with many other medications and foods, leading to a hypertensive crisis that can potentially be fatal. SSRIs can cause sexual dysfunction and compulsive yawning as side effects. Discontinuation of SSRIs can lead to withdrawal symptoms which include flu-like symptoms, as well as [[brain zaps]].

SSRIs are reported to have fewer side effects than older antidepressants like [[MAOI|monoamine oxidase inhibitors]] and [https://psychonautwiki.org/wiki/Antidepressants#Tricyclic_antidepressants_.28TCA.29_and_tetracyclic_antidepressants_.28TeCAs.29 tricyclic antidepressants].{{citation needed}} [[MAOI|Monoamine oxidase inhibitors]] also interact with many other medications and foods, leading to a hypertensive crisis that can potentially be fatal. SSRIs can cause sexual dysfunction and compulsive yawning as side effects. Discontinuation of SSRIs can lead to withdrawal symptoms which include flu-like symptoms, as well as [[brain zaps]].

[[File:SSRIs.png|400px|thumbnail|right|A comparison of the structure of commonly prescribed SSRIs.]]

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 SSRIs can be dangerous when used in combination with other substances that increase or modulate serotonin such as [[MDMA]] and [[MAOI|Monoamine Oxidase Inhibitors]] (MAOIs). A combination with these substances can lead to [[serotonin syndrome]] and potentially be fatal. SSRIs do not work for everyone and take 3-6 weeks to start having noticeable effects.<ref>{{Citation | year=2021 | title=Do Antidepressants Work Right Away? | url=https://psychcentral.com/depression/how-long-do-antidepressants-take-to-work}}</ref>
-SSRIs are reported to have fewer side effects than older antidepressants like [[MAOI|monoamine oxidase inhibitors]] and [[tricyclic antidepressants]].{{citation needed}} [[MAOI|Monoamine oxidase inhibitors]] also interact with many other medications and foods, leading to a hypertensive crisis that can potentially be fatal. SSRIs can cause sexual dysfunction and compulsive yawning as side effects. Discontinuation of SSRIs can lead to withdrawal symptoms which include flu-like symptoms, as well as [[brain zaps]].
+SSRIs are reported to have fewer side effects than older antidepressants like [[MAOI|monoamine oxidase inhibitors]] and [https://psychonautwiki.org/wiki/Antidepressants#Tricyclic_antidepressants_.28TCA.29_and_tetracyclic_antidepressants_.28TeCAs.29 tricyclic antidepressants].{{citation needed}} [[MAOI|Monoamine oxidase inhibitors]] also interact with many other medications and foods, leading to a hypertensive crisis that can potentially be fatal. SSRIs can cause sexual dysfunction and compulsive yawning as side effects. Discontinuation of SSRIs can lead to withdrawal symptoms which include flu-like symptoms, as well as [[brain zaps]].
 [[File:SSRIs.png|400px|thumbnail|right|A comparison of the structure of commonly prescribed SSRIs.]]