Unique substance warnings: Difference between revisions
>David Hedlund |
>David Hedlund |
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===[[Dosage]]=== | ===[[Dosage]]=== | ||
====Steep dose response curve==== | |||
* [[2C-B]]: "There is a steep dose response curve. Over the 12 to 24 milligram range, every 2 milligrams can make a profound increase or change of response. Initially, one should go lightly, and increase the dosage in subsequent trials by small increments."<ref>http://www.erowid.org/library/books_online/pihkal/pihkal020.shtml</ref> | * [[2C-B]]: "There is a steep dose response curve. Over the 12 to 24 milligram range, every 2 milligrams can make a profound increase or change of response. Initially, one should go lightly, and increase the dosage in subsequent trials by small increments."<ref>http://www.erowid.org/library/books_online/pihkal/pihkal020.shtml</ref> | ||
* [[2C-P]]: 2C-P is known to have a steep dose-response curve, as little as a few extra milligrams separating a manageable dose and an overdose. Also, 2C-P can have a very slow onset if ingested, and peak effects reportedly do not occur for 3 to 5 hours. "There was one report of an experience in which a single dosage of 16 mg was clearly an overdose, with the entire experiment labeled a physical disaster, not to be repeated. A consistent observation is that there may not be too much latitude in dosage between that which would be modest, or adequate, and that which would be excessive. The need for individual titration would be most important with this compound."<ref>http://isomerdesign.com/PiHKAL/read.php?id=36&domain=pk</ref> | * [[2C-P]]: 2C-P is known to have a steep dose-response curve, as little as a few extra milligrams separating a manageable dose and an overdose. Also, 2C-P can have a very slow onset if ingested, and peak effects reportedly do not occur for 3 to 5 hours. "There was one report of an experience in which a single dosage of 16 mg was clearly an overdose, with the entire experiment labeled a physical disaster, not to be repeated. A consistent observation is that there may not be too much latitude in dosage between that which would be modest, or adequate, and that which would be excessive. The need for individual titration would be most important with this compound."<ref>http://isomerdesign.com/PiHKAL/read.php?id=36&domain=pk</ref> | ||
====Slow onset==== | |||
* [[2C-P]]: Onset 1-3 hours. - https://www.erowid.org/library/books_online/pihkal/pihkal036.shtml | |||
===[[Routes of administration]]=== | ===[[Routes of administration]]=== |