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Pregabalin: Difference between revisions
>Nutmeg enjoyer 11 m I added to the pharmacology section that reduction in glutamate and acetylcholine release caused by Ca channel blockage might be the cause behind why pregabalin can induce dissocative and derlaint like effects. I have talked to lots of pregabalin users and have used it for years, high doses are known for ketamine and delirious like hallucinations. This would make sense because less glutamate available means less of it activates nmda, and same with aCh receptors. |
>Nutmeg enjoyer 11 I added the fact that pregabalin is effective for alcohol wihtdrawal seizures and added the citation. |
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===Seizures=== | ===Seizures=== | ||
Pregabalin is useful when added to other treatments, when those other treatments are not controlling partial epilepsy. Its use alone is less effective than some other seizure medications. It is unclear how it compares to gabapentin for this use. | Pregabalin is useful when added to other treatments, when those other treatments are not controlling partial epilepsy. Its use alone is less effective than some other seizure medications. It is unclear how it compares to gabapentin for this use. Pregabalin has also been shown to be effective against alcohol withdrawal induced seizures <ref>https://academic.oup.com/alcalc/article/41/4/399/162460</ref>. | ||
===Neuropathic pain=== | ===Neuropathic pain=== | ||