Benzodiazepines: Difference between revisions

Line 99:

! scope="col" | '''Structure'''

|-

| [[~~Bromazepam~~]] || ~~H |~~| =O |~~| H~~2 || || C5H4N || H || Br || [[File:~~Bromazepam~~.svg|170px]]

| [[Chlordiazepoxide]] || || NHCH3 || H || O || C6H5 || H || Cl || [[File:Chlordiazepoxide.svg|170px]]

|-

| [[~~Cinolazepam~~]] || ~~CH2CH2≡N~~ || =O || ~~HOH~~ || || C6H4F || H || Cl || [[File:~~Cinolazepam~~.svg|170px]]

| [[Bromazepam]] || H || =O || H || || C5H4N || H || Br || [[File:Bromazepam.svg|170px]]

|-

| [[~~Clonazepam~~]] || ~~H || =O || H~~2 || || C6H4Cl || H || ~~NO2~~ || [[File:~~Clonazepam~~.svg|170px]]

| [[Cinolazepam]] || CH2CH2≡N || =O || OH || || C6H4F || H || Cl || [[File:Cinolazepam.svg|170px]]

|-

| [[~~Diazepam~~]] || ~~CH3~~ || =O || H~~2~~ || || C6H5 || H || Cl || [[File:~~Diazepam~~.svg|170px]]

| [[Clonazepam]] || H || =O || H || || C6H4Cl || H || NO2 || [[File:Clonazepam.svg|170px]]

|-

| [[~~Diclazepam~~]] || CH3 || =O || H~~2~~ || || C6H4Cl || H || Cl || [[File:~~Diclazepam~~.svg|170px]]

| [[Diazepam]] || CH3 || =O || H || || C6H5 || H || Cl || [[File:Diazepam.svg|170px]]

|-

| [[~~Flubromazepam~~]] || H || =O || H~~2~~ || || C6H4F || H || Br || [[File:~~Flubromazepam~~.svg|170px]]

| [[Diclazepam]] || CH3 || =O || H || || C6H4Cl || H || Cl || [[File:Diclazepam.svg|170px]]

|-

| [[~~Flunitrazepam~~]] || ~~CH3~~ || =O || H~~2~~ || || C6H4F || H || ~~NO2~~ || [[File:~~Flunitrazepam~~.svg|170px]]

| [[Flubromazepam]] || H || =O || H || || C6H4F || H || Br || [[File:Flubromazepam.svg|170px]]

|-

| [[~~Lorazepam~~]] || H || =O || ~~HOH~~ || || C6H4Cl || H || Cl || [[File:~~Lorazepam~~.svg|170px]]

| [[Flunitrazepam]] || CH3 || =O || H || || C6H4F || H || NO2 || [[File:Flunitrazepam.svg|170px]]

|-

| [[~~Meclonazepam~~]] || H || =O || ~~HCH3~~ || || C6H4Cl || H || ~~NO2~~ || [[File:~~Meclonazepam~~.svg|170px]]

| [[Lorazepam]] || H || =O || OH || || C6H4Cl || H || Cl || [[File:Lorazepam.svg|170px]]

|-

| [[~~Nifoxipam~~]] || H || =O || ~~HOH~~ || || C6H4F || H || NO2 || [[File:~~Nifoxipam~~.svg|170px]]

| [[Meclonazepam]] || H || =O || CH3 || || C6H4Cl || H || NO2 || [[File:Meclonazepam.svg|170px]]

|-

| [[~~Oxazepam~~]] || H || =O || ~~HOH~~ || || C6H5 || H || Cl || [[File:~~Oxazepam~~.svg|170px]]

| [[Nifoxipam]] || H || =O || OH || || C6H4F || H || NO2 || [[File:Nifoxipam.svg|170px]]

|-

| [[~~Temazepam~~]] || ~~CH3~~ || =O || ~~HOH~~ || || C6H5 || H || Cl || [[File:~~Temazepam~~.svg|170px]]

| [[Oxazepam]] || H || =O || OH || || C6H5 || H || Cl || [[File:Oxazepam.svg|170px]]

|-

| [[~~Alprazolam~~]] || C(CH3~~)=N-~~ || =N- || ~~H2~~ || || C6H5 || H || Cl || [[File:~~Alprazolam~~.svg|170px]]

| [[Temazepam]] || CH3 || =O || OH || || C6H5 || H || Cl || [[File:Temazepam.svg|170px]]

|-

| [[~~Clonazolam~~]] || C(CH3)=N- || =N- || H~~2~~ || || C6H4Cl || H || ~~NO2~~ || [[File:~~Clonazolam~~.svg|170px]]

| [[Alprazolam]] || C(CH3)=N- || =N- || H || || C6H5 || H || Cl || [[File:Alprazolam.svg|170px]]

|-

| [[~~Flubromazolam~~]] || C(CH3)=N- || =N- || H~~2~~ || || C6H4F || H || Br || [[File:~~Flubromazolam~~.svg|170px]]

| [[Clonazolam]] || C(CH3)=N- || =N- || H || || C6H4Cl || H || NO2 || [[File:Clonazolam.svg|170px]]

|-

| [[~~Flunitrazolam~~]] || C(CH3)=N- || =N- || H~~2~~ || || C6H4F || H || ~~NO2~~ || [[File:~~Flunitrazolam~~.svg|170px]]

| [[Flubromazolam]] || C(CH3)=N- || =N- || H || || C6H4F || H || Br || [[File:Flubromazolam.svg|170px]]

|-

| [[~~Midazolam~~]] || C(CH3)=N- || =N- || H~~2~~ || || C6H4F || H || Cl || [[File:~~Midazolam~~.svg|170px]]

| [[Flunitrazolam]] || C(CH3)=N- || =N- || H || || C6H4F || H || NO2 || [[File:Flunitrazolam.svg|170px]]

|-

| [[~~Pyrazolam~~]] || C(CH3)=N- || =N- || H~~2~~ || || C5H4N || H || Br || [[File:~~Pyrazolam~~.svg|170px]]

| [[Midazolam]] || C(CH3)=N- || =N- || H || || C6H4F || H || Cl || [[File:Midazolam.svg|170px]]

|-

| [[~~Triazolam~~]] || C(CH3)=N- || =N- || H~~2~~ || || C6H4Cl || H || Cl || [[File:~~Triazolam~~.svg|170px]]

| [[Pyrazolam]] || C(CH3)=N- || =N- || H || || C5H4N || H || Br || [[File:Pyrazolam.svg|170px]]

|-

| [[~~Chlordiazepoxide~~]] || ~~- ||~~ (~~-)NHCH~~3 || H~~2~~ || O || C6H5 || H || Cl || [[File:~~Chlordiazepoxide~~.svg|170px]]

| [[Triazolam]] || C(CH3)=N- || =N- || H || || C6H4Cl || H || Cl || [[File:Triazolam.svg|170px]]

|-

| [[Flumazenil]] || CH=N- || C(C3H5O2)- || H~~2~~ || CH3 || =O || H || F || [[File:Flumazenil.svg|170px]]

| [[Flumazenil]] || CH=N- || C(C3H5O2)- || H || CH3 || =O || H || F || [[File:Flumazenil.svg|170px]]

|-

| [[Bretazenil]] || CH=N- || C(C5H9O2)- || ~~HCH~~2CH2- || CH2- || =O || Br || H || [[File:Bretazenil.svg|170px]]

| [[Bretazenil]] || CH=N- || C(C5H9O2)- || CH2CH2- || CH2- || =O || Br || H || [[File:Bretazenil.svg|170px]]

|-

| [[Clozapine]] || H || CH=CH- || CH=CH(Cl)- || || C5H11N2 || H || H || [[File:Clozapine.svg|170px]]

@@ Line 99: / Line 99: @@
 ! scope="col" | '''Structure'''
 |-
-| [[Bromazepam]] || H || =O || H<sub>2</sub> ||  || C<sub>5</sub>H<sub>4</sub>N || H || Br || [[File:Bromazepam.svg|170px]]
+| [[Chlordiazepoxide]] ||  || NHCH<sub>3</sub> || H || O || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Chlordiazepoxide.svg|170px]]
 |-
-| [[Cinolazepam]] || CH<sub>2</sub>CH<sub>2</sub>≡N || =O || HOH ||  || C<sub>6</sub>H<sub>4</sub>F || H || Cl || [[File:Cinolazepam.svg|170px]]
+| [[Bromazepam]] || H || =O || H ||  || C<sub>5</sub>H<sub>4</sub>N || H || Br || [[File:Bromazepam.svg|170px]]
 |-
-| [[Clonazepam]] || H || =O || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || NO<sub>2</sub> || [[File:Clonazepam.svg|170px]]
+| [[Cinolazepam]] || CH<sub>2</sub>CH<sub>2</sub>≡N || =O || OH ||  || C<sub>6</sub>H<sub>4</sub>F || H || Cl || [[File:Cinolazepam.svg|170px]]
 |-
-| [[Diazepam]] || CH<sub>3</sub> || =O || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Diazepam.svg|170px]]
+| [[Clonazepam]] || H || =O || H ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || NO<sub>2</sub> || [[File:Clonazepam.svg|170px]]
 |-
-| [[Diclazepam]] || CH<sub>3</sub> || =O || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || Cl || [[File:Diclazepam.svg|170px]]
+| [[Diazepam]] || CH<sub>3</sub> || =O || H ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Diazepam.svg|170px]]
 |-
-| [[Flubromazepam]] || H || =O || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>F || H || Br || [[File:Flubromazepam.svg|170px]]
+| [[Diclazepam]] || CH<sub>3</sub> || =O || H ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || Cl || [[File:Diclazepam.svg|170px]]
 |-
-| [[Flunitrazepam]] || CH<sub>3</sub> || =O || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>F || H || NO<sub>2</sub> || [[File:Flunitrazepam.svg|170px]]
+| [[Flubromazepam]] || H || =O || H ||  || C<sub>6</sub>H<sub>4</sub>F || H || Br || [[File:Flubromazepam.svg|170px]]
 |-
-| [[Lorazepam]] || H || =O || HOH ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || Cl || [[File:Lorazepam.svg|170px]]
+| [[Flunitrazepam]] || CH<sub>3</sub> || =O || H ||  || C<sub>6</sub>H<sub>4</sub>F || H || NO<sub>2</sub> || [[File:Flunitrazepam.svg|170px]]
 |-
-| [[Meclonazepam]] || H || =O || HCH<sub>3</sub> ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || NO<sub>2</sub> || [[File:Meclonazepam.svg|170px]]
+| [[Lorazepam]] || H || =O || OH ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || Cl || [[File:Lorazepam.svg|170px]]
 |-
-| [[Nifoxipam]] || H || =O || HOH ||  || C<sub>6</sub>H<sub>4</sub>F || H || NO<sub>2</sub> || [[File:Nifoxipam.svg|170px]]
+| [[Meclonazepam]] || H || =O || CH<sub>3</sub> ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || NO<sub>2</sub> || [[File:Meclonazepam.svg|170px]]
 |-
-| [[Oxazepam]] || H || =O || HOH ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Oxazepam.svg|170px]]
+| [[Nifoxipam]] || H || =O || OH ||  || C<sub>6</sub>H<sub>4</sub>F || H || NO<sub>2</sub> || [[File:Nifoxipam.svg|170px]]
 |-
-| [[Temazepam]] || CH<sub>3</sub> || =O || HOH ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Temazepam.svg|170px]]
+| [[Oxazepam]] || H || =O || OH ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Oxazepam.svg|170px]]
 |-
-| [[Alprazolam]] || C(CH<sub>3</sub>)=N- || =N- || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Alprazolam.svg|170px]]
+| [[Temazepam]] || CH<sub>3</sub> || =O || OH ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Temazepam.svg|170px]]
 |-
-| [[Clonazolam]] || C(CH<sub>3</sub>)=N- || =N- || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || NO<sub>2</sub> || [[File:Clonazolam.svg|170px]]
+| [[Alprazolam]] || C(CH<sub>3</sub>)=N- || =N- || H ||  || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Alprazolam.svg|170px]]
 |-
-| [[Flubromazolam]] || C(CH<sub>3</sub>)=N- || =N- || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>F || H || Br || [[File:Flubromazolam.svg|170px]]
+| [[Clonazolam]] || C(CH<sub>3</sub>)=N- || =N- || H ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || NO<sub>2</sub> || [[File:Clonazolam.svg|170px]]
 |-
-| [[Flunitrazolam]] || C(CH<sub>3</sub>)=N- || =N- || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>F || H || NO<sub>2</sub> || [[File:Flunitrazolam.svg|170px]]
+| [[Flubromazolam]] || C(CH<sub>3</sub>)=N- || =N- || H ||  || C<sub>6</sub>H<sub>4</sub>F || H || Br || [[File:Flubromazolam.svg|170px]]
 |-
-| [[Midazolam]] || C(CH<sub>3</sub>)=N- || =N- || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>F || H || Cl || [[File:Midazolam.svg|170px]]
+| [[Flunitrazolam]] || C(CH<sub>3</sub>)=N- || =N- || H ||  || C<sub>6</sub>H<sub>4</sub>F || H || NO<sub>2</sub> || [[File:Flunitrazolam.svg|170px]]
 |-
-| [[Pyrazolam]] || C(CH<sub>3</sub>)=N- || =N- || H<sub>2</sub> ||  || C<sub>5</sub>H<sub>4</sub>N || H || Br || [[File:Pyrazolam.svg|170px]]
+| [[Midazolam]] || C(CH<sub>3</sub>)=N- || =N- || H ||  || C<sub>6</sub>H<sub>4</sub>F || H || Cl || [[File:Midazolam.svg|170px]]
 |-
-| [[Triazolam]] || C(CH<sub>3</sub>)=N- || =N- || H<sub>2</sub> ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || Cl || [[File:Triazolam.svg|170px]]
+| [[Pyrazolam]] || C(CH<sub>3</sub>)=N- || =N- || H ||  || C<sub>5</sub>H<sub>4</sub>N || H || Br || [[File:Pyrazolam.svg|170px]]
 |-
-| [[Chlordiazepoxide]] || - || (-)NHCH<sub>3</sub> || H<sub>2</sub> || O || C<sub>6</sub>H<sub>5</sub> || H || Cl || [[File:Chlordiazepoxide.svg|170px]]
+| [[Triazolam]] || C(CH<sub>3</sub>)=N- || =N- || H ||  || C<sub>6</sub>H<sub>4</sub>Cl || H || Cl || [[File:Triazolam.svg|170px]]
 |-
-| [[Flumazenil]] || CH=N- || C(C<sub>3</sub>H<sub>5</sub>O<sub>2</sub>)- || H<sub>2</sub> || CH<sub>3</sub> || =O || H || F || [[File:Flumazenil.svg|170px]]
+| [[Flumazenil]] || CH=N- || C(C<sub>3</sub>H<sub>5</sub>O<sub>2</sub>)- || H || CH<sub>3</sub> || =O || H || F || [[File:Flumazenil.svg|170px]]
 |-
-| [[Bretazenil]] || CH=N- || C(C<sub>5</sub>H<sub>9</sub>O<sub>2</sub>)- || HCH<sub>2</sub>CH<sub>2</sub>- || CH<sub>2</sub>- || =O || Br || H || [[File:Bretazenil.svg|170px]]
+| [[Bretazenil]] || CH=N- || C(C<sub>5</sub>H<sub>9</sub>O<sub>2</sub>)- || CH<sub>2</sub>CH<sub>2</sub>- || CH<sub>2</sub>- || =O || Br || H || [[File:Bretazenil.svg|170px]]
 |-
 | [[Clozapine]] || H || CH=CH- || CH=CH(Cl)- ||  || C<sub>5</sub>H<sub>11</sub>N<sub>2</sub> || H || H || [[File:Clozapine.svg|170px]]