This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Substituted tropanes: Difference between revisions
>Unity Expanded introduction. |
>Tracer Supplemented. Removed non tropane substances. |
||
| Line 1: | Line 1: | ||
[[File:tropane.png|thumb|200px|right|General tropane molecule]] | [[File:tropane.png|thumb|200px|right|General tropane molecule]] | ||
{{Stub}} | {{Stub}} | ||
'''Substituted tropanes''' are a group of [[psychoactive compounds]] that include a tropane ring in their structure. Prominent examples include certain [[stimulants]] like [[cocaine]] and its derivatives as well as [[deliriants]] like [[atropine]] and [[scopolamine]]. | '''Substituted tropanes''' (or simply '''tropanes''') are a group of [[psychoactive compounds]] that include a tropane ring in their structure. Prominent examples include certain [[stimulants]] like [[cocaine]] and its derivatives as well as [[deliriants]] like [[atropine]] and [[scopolamine]]. | ||
==Chemistry== | ==Chemistry== | ||
Tropanes are molecules which contain a substituted tropane ring in their structure. Tropane is a nitrogen-containing bicyclic organic molecule which consists of a [[piperidine]] and [[pyrrolidine]] ring fused at carbons R<sub>1</sub> and R<sub>5</sub> along with an additional methyl substitution at R<sub>N</sub>. It is mainly known for a group of [[alkaloids]] derived from it. Tropane alkaloids are commonly substituted at R<sub>3</sub> with an ether bridge (as seen in [[scopolamine]], [[atropine]], [[hyoscyamine]], and [[cocaine]]). Synthetic analogs of tropane alkaloids also exist, such as the phenyltropanes. They are not considered to be alkaloids per definition. | |||
==Pharmacology== | ==Pharmacology== | ||
| Line 11: | Line 11: | ||
==Examples== | ==Examples== | ||
Substituted tropanes are seen throughout organic chemistry and include psychoactive and anaesthetic compounds. | |||
'''Anticholinergic drugs:''' | '''Anticholinergic drugs:''' | ||
*[[Atropine]] | *[[Atropine]] | ||
*[[Benzatropine]] | |||
*[[Hyoscyamine]] | *[[Hyoscyamine]] | ||
*[[Scopolamine]] | *[[Scopolamine]] | ||
'''Stimulant drugs:''' | '''Stimulant drugs:''' | ||
*[[2-HO-Cocaine]] | |||
*[[4-Fl-Cocaine]] | |||
*[[Cocaine]] | *[[Cocaine]] | ||
*[[REC]] | |||
*[[RTI-111]] | *[[RTI-111]] | ||
*[[RTI-126]] | *[[RTI-126]] | ||
*[[RTI-31]] | *[[RTI-31]] | ||
*[[Tesofensine]] | *[[Tesofensine]] | ||
| Line 41: | Line 37: | ||
==External links== | ==External links== | ||
*[https://en.wikipedia.org/wiki/Tropane Tropane (Wikipedia)] | |||
*[[wikipedia:Tropane alkaloid|Tropane alkaloid (Wikipedia)]] | *[[wikipedia:Tropane alkaloid|Tropane alkaloid (Wikipedia)]] | ||