Gabapentin: Difference between revisions

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[[Subjective effects]] include mild to moderate [[anxiety suppression]], [[pain relief]], and [[muscle relaxation]]. Its analgesic and anxiolytic effects provide gabapentin with some recreational potential in a manner that can be compared to a mild [[benzodiazepine]]. However, these recreational effects diminish very quickly with repeated usage and are most commonly reported by those who do not have a tolerance to this compound.

Gabapentin ~~is lipophilic, meaning it is only well absorbed when bonded~~ to ~~fats~~, ~~so one should eat a heavier meal containing lots~~ of ~~fats and preferably also include an acidic drink such as soda to aid in absorption~~.~~{{citation needed}}~~

Gabapentin should be taken with food as fasting will lead to less gabapentin exposure. The fat content of the food does not matter, though. <ref>[https://www.ncbi.nlm.nih.gov/m/pubmed/20137764/] The effect of food with varying fat content on the clinical pharmacokinetics of gabapentin after oral administration of gabapentin enacarbil.</ref>

Gabapentin is considered to have low abuse potential compared to most recreational depressants. However, chronic use can lead to physical dependence. Additionally, there is a risk of lethal overdose when it is combined with other depressants (a relatively common practice considering its weak effects). As a result, it is highly advised to use [[harm reduction practices]] if using this substance.

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 [[Subjective effects]] include mild to moderate [[anxiety suppression]], [[pain relief]], and [[muscle relaxation]]. Its analgesic and anxiolytic effects provide gabapentin with some recreational potential in a manner that can be compared to a mild [[benzodiazepine]]. However, these recreational effects diminish very quickly with repeated usage and are most commonly reported by those who do not have a tolerance to this compound.
-Gabapentin is lipophilic, meaning it is only well absorbed when bonded to fats, so one should eat a heavier meal containing lots of fats and preferably also include an acidic drink such as soda to aid in absorption.{{citation needed}}
+Gabapentin should be taken with food as fasting will lead to less gabapentin exposure. The fat content of the food does not matter, though. <ref>[https://www.ncbi.nlm.nih.gov/m/pubmed/20137764/] The effect of food with varying fat content on the clinical pharmacokinetics of gabapentin after oral administration of gabapentin enacarbil.</ref>
 Gabapentin is considered to have low abuse potential compared to most recreational depressants. However, chronic use can lead to physical dependence. Additionally, there is a risk of lethal overdose when it is combined with other depressants (a relatively common practice considering its weak effects). As a result, it is highly advised to use [[harm reduction practices]] if using this substance.