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Benzodiazepines: Difference between revisions
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The [[anticonvulsant]] properties of benzodiazepines may be, in part or entirely, due to binding to voltage-dependent sodium channels rather than benzodiazepine receptors.<ref>Benzodiazepines, but not beta-carbolines, limit high-frequency repetitive firing of action potentials of spinal cord neurons in cell culture. (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/2450203</ref> | The [[anticonvulsant]] properties of benzodiazepines may be, in part or entirely, due to binding to voltage-dependent sodium channels rather than benzodiazepine receptors.<ref>Benzodiazepines, but not beta-carbolines, limit high-frequency repetitive firing of action potentials of spinal cord neurons in cell culture. (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/2450203</ref> | ||
Benzodiazepines function as weak adenosine reuptake inhibitors. It has been suggested that some of their [[anticonvulsant]], [[anxiolytic]], and [[muscle relaxant]] effects may be in part mediated by this action.<ref>[The mechanisms of depression by benzodiazepines, barbiturates and propofol of excitatory synaptic transmissions mediated by adenosine neuromodulation]. (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/16780077</ref> | |||
==Subjective effects== | ==Subjective effects== | ||