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3-HO-PCE: Difference between revisions
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Following other substances of its class, particularly [[methoxetamine]] (MXE), [[phencyclidine]] (PCP), and [[3-MeO-PCE]], it is speculated to to be able to induce a state known as "[[dissociatives#Subjective effects|dissociative anesthesia]]". Early reports suggest that this state is difficult to reach relative to other [[dissociatives]], and its general effects profile has been characterized as "lying halfway between [[3-MeO-PCP]] and [[3-MeO-PCE]]." | Following other substances of its class, particularly [[methoxetamine]] (MXE), [[phencyclidine]] (PCP), and [[3-MeO-PCE]], it is speculated to to be able to induce a state known as "[[dissociatives#Subjective effects|dissociative anesthesia]]". Early reports suggest that this state is difficult to reach relative to other [[dissociatives]], and its general effects profile has been characterized as "lying halfway between [[3-MeO-PCP]] and [[3-MeO-PCE]]." | ||
There is a lack of data of the pharmacological properties, metabolism and toxicity of 3-HO-PCE. To date, there have been no analytical studies conducted on samples of 3-HO-PCE distributed through the grey market via independent laboratories.<ref name="PCP2MXE /> Due to an unknown toxicity profile and likely similar habit-forming properties shared by other hydroxylanated arylcyclohexylamines, it is strongly recommended that one use proper [[harm reduction practices]] if choosing to use this substance. | There is a lack of data of the pharmacological properties, metabolism and toxicity of 3-HO-PCE. To date, there have been no analytical studies conducted on samples of 3-HO-PCE distributed through the grey market via independent laboratories.<ref name="PCP2MXE" /> Due to an unknown toxicity profile and likely similar habit-forming properties shared by other hydroxylanated arylcyclohexylamines, it is strongly recommended that one use proper [[harm reduction practices]] if choosing to use this substance. | ||
==History and culture== | ==History and culture== | ||
{{historyStub}} | {{historyStub}} | ||
On October 18, 2012 the Advisory Council on the Misuse of Drugs in the United Kingdom released a report about methoxetamine, saying that the "harms of methoxetamine are commensurate with Class B of the Misuse of Drugs Act (1971)", despite the fact that the act does not classify drugs based on harm. The report went on to suggest that all analogues of MXE should also become class B drugs and suggested a catch-all clause covering both existing and unresearched arylcyclohexamines, which includes 3-HO-PCE.<ref> "[https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/119087/methoxetamine2012.pdf (ACMD) Methoxetamine Report (2012)]" (PDF). UK Home Office. 2012-10-18. p. 14. Retrieved 2015-06-24.</ref> | On October 18, 2012 the Advisory Council on the Misuse of Drugs in the United Kingdom released a report about methoxetamine, saying that the "harms of methoxetamine are commensurate with Class B of the Misuse of Drugs Act (1971)", despite the fact that the act does not classify drugs based on harm. The report went on to suggest that all analogues of MXE should also become class B drugs and suggested a catch-all clause covering both existing and unresearched arylcyclohexamines, which includes 3-HO-PCE.<ref>"[https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/119087/methoxetamine2012.pdf (ACMD) Methoxetamine Report (2012)]" (PDF). UK Home Office. 2012-10-18. p. 14. Retrieved 2015-06-24.</ref> | ||
==Chemistry== | ==Chemistry== | ||
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==Legal status== | ==Legal status== | ||
{{legalStub}} | {{legalStub}} | ||
*'''Germany:''' 3-HO-PCE is not a controlled substance under the BtMG.<ref>http://www.gesetze-im-internet.de/btmg_1981/anlage_i.html</ref> It is legal, as long as it is not sold for human consumption, according to §2 AMG.<ref>https://www.gesetze-im-internet.de/amg_1976/__2.html</ref> | |||
*'''United Kingdom:''' 3-HO-PCE is a class B drug in the UK and is illegal to possess, produce, supply, or import. As a derivative of 1-Phenylcyclohexylamine where the amine has been replaced with a 1-piperidyl group, further substituted in the phenyl ring with a hydroxy substituent, it is covered by the arylcyclohexylamine generic clause added to the Misuse of Drugs Act by S.I. 2013/239, which came into effect on the 26th February 2013.<ref>The Misuse of Drugs Act 1971 (Amendment) Order 2013 (Legislation.gov.uk) | http://www.legislation.gov.uk/uksi/2013/239/introduction/made</ref> | *'''United Kingdom:''' 3-HO-PCE is a class B drug in the UK and is illegal to possess, produce, supply, or import. As a derivative of 1-Phenylcyclohexylamine where the amine has been replaced with a 1-piperidyl group, further substituted in the phenyl ring with a hydroxy substituent, it is covered by the arylcyclohexylamine generic clause added to the Misuse of Drugs Act by S.I. 2013/239, which came into effect on the 26th February 2013.<ref>The Misuse of Drugs Act 1971 (Amendment) Order 2013 (Legislation.gov.uk) | http://www.legislation.gov.uk/uksi/2013/239/introduction/made</ref> | ||