1B-LSD: Difference between revisions

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==History and culture==
==History and culture==
1B-LSD first appeared on the online research chemical market in September 2018.<ref>1B-LSD (Google Trends) | https://trends.google.com/trends/explore?q=1p-lsd</ref>  
1B-LSD first appeared on the online research chemical market in September 2018.<ref>1B-LSD (Google Trends) | https://trends.google.com/trends/explore?q=1p-lsd</ref>  
Although it was likely discovered in an academic setting, it is unknown who first synthesized 1B-LSD, as the substance does not appear in any academic literature pre-dating its arrival on the research chemical market.<ref>Brandt, S. D. (2015, October 12). Return of the lysergamides. Part I: Analytical and behavioral characterization of 1‐propionyl‐d‐lysergic acid diethylamide (1P‐LSD). https://doi.org/10.1002/dta.1884</ref>  
It is unknown who first synthesized 1B-LSD, as the substance does not appear in any academic literature pre-dating its arrival on the research chemical market.<ref>Brandt, S. D. (2015, October 12). Return of the lysergamides. Part I: Analytical and behavioral characterization of 1‐propionyl‐d‐lysergic acid diethylamide (1P‐LSD). https://doi.org/10.1002/dta.1884</ref>  
Interestingly, the future usage of 1-akylated lysergamide derivatives as a means to bypass controlled substance laws banning [[LSD]] as a precursor was foreseen in a DEA report from 1988:
Interestingly, the future usage of 1-akylated lysergamide derivatives as a means to bypass controlled substance laws banning [[LSD]] as a precursor was foreseen in a DEA report from 1988:
{{quote3|text=...a reduction in hallucinogenic activity may become acceptable to the U.S. clandestine chemist when he notes that lysergic acid amide is listed as a Schedule III substance in the CFR; therefore, structurally similar substances of this compound are exempted from the CsA amendment. A lucid argument can then be made that lysergic acid N,N-dimethylamide is derived from lysergic acid amide rather than LSD. Carrying this theme to the next logical step one would then assume that the 1-alkyl and 1-acyl derivatives of the N,N-dimethyl isomer would also not be controlled by the CsA amendment. |author=Donald A. Cooper|source=Future Synthetic Drugs of Abuse, 1988<ref>Cooper, D. A. (1988, March). Future synthetic drugs of abuse. In Proceedings of the international symposium on the forensic aspects of controlled substances: March (Vol. 28, p. 79). https://www.erowid.org/library/books_online/future_synthetic/future_synthetic.shtml</ref>}}
{{quote3|text=...a reduction in hallucinogenic activity may become acceptable to the U.S. clandestine chemist when he notes that lysergic acid amide is listed as a Schedule III substance in the CFR; therefore, structurally similar substances of this compound are exempted from the CsA amendment. A lucid argument can then be made that lysergic acid N,N-dimethylamide is derived from lysergic acid amide rather than LSD. Carrying this theme to the next logical step one would then assume that the 1-alkyl and 1-acyl derivatives of the N,N-dimethyl isomer would also not be controlled by the CsA amendment. |author=Donald A. Cooper|source=Future Synthetic Drugs of Abuse, 1988<ref>Cooper, D. A. (1988, March). Future synthetic drugs of abuse. In Proceedings of the international symposium on the forensic aspects of controlled substances: March (Vol. 28, p. 79). https://www.erowid.org/library/books_online/future_synthetic/future_synthetic.shtml</ref>}}
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