MiPLA: Difference between revisions

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===Dependence and abuse potential===

~~Although no formal studies have been conducted~~, it is ~~not unreasonable~~ to ~~assume that as with LSD itself, MIPLA is~~ [[Addiction potential::~~not habit-forming~~]] and that the ~~desire~~ to ~~use it can actually decrease~~ with ~~use~~.

Like other [[serotonergic psychedelics]], MIPLA is believed to have a [[Addiction potential::low potential for abuse and dependence]]. This is owing to its structural and pharmacological similarities with [[LSD]]. See [[LSD#Dependence and abuse|this section]] to learn more about the dependence and abuse potential of LSD. It should be noted that all claims related to the abuse potential of MIPLA are preliminary and based on anecdotal (as opposed to clinical) evidence and should be interpreted with caution.

~~Tolerance~~ to the effects of MIPLA ~~are built~~ [[Time to full tolerance::almost immediately after ingestion]]. After that, it ~~takes~~ about [[Time to half tolerance::5-7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::14 days]] to be ~~back at~~ baseline (in the absence of further consumption)~~. MIPLA presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the use of MIPLA all psychedelics will have a reduced effect~~.

As with LSD, tolerance to the effects of MIPLA forms [[Time to full tolerance::almost immediately after ingestion]]. After that, it is assumed to take about [[Time to half tolerance::5-7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::14 days]] to be return to baseline (in the absence of further consumption).

~~Owing~~ to its activity at the 5-HT<sub>2A</sub> receptor, MIPLA ~~presents~~ cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of MIPLA all psychedelics will have a reduced effect.

Due to its activity at the 5-HT<sub>2A</sub> receptor, MIPLA produces cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of MIPLA all psychedelics will have a reduced effect.

===Dangerous interactions===

@@ Line 146: / Line 146: @@
 ===Dependence and abuse potential===
-Although no formal studies have been conducted, it is not unreasonable to assume that as with LSD itself, MIPLA is [[Addiction potential::not habit-forming]] and that the desire to use it can actually decrease with use.
+Like other [[serotonergic psychedelics]], MIPLA is believed to have a [[Addiction potential::low potential for abuse and dependence]]. This is owing to its structural and pharmacological similarities with [[LSD]]. See [[LSD#Dependence and abuse|this section]] to learn more about the dependence and abuse potential of LSD. It should be noted that all claims related to the abuse potential of MIPLA are preliminary and based on anecdotal (as opposed to clinical) evidence and should be interpreted with caution.
-Tolerance to the effects of MIPLA are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::5-7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::14 days]] to be back at baseline (in the absence of further consumption). MIPLA presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the use of MIPLA all psychedelics will have a reduced effect.
+As with LSD, tolerance to the effects of MIPLA forms [[Time to full tolerance::almost immediately after ingestion]]. After that, it is assumed to take about [[Time to half tolerance::5-7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::14 days]] to be return to baseline (in the absence of further consumption).
-Owing to its activity at the 5-HT<sub>2A</sub> receptor, MIPLA presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of MIPLA all psychedelics will have a reduced effect.
+Due to its activity at the 5-HT<sub>2A</sub> receptor, MIPLA produces cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of MIPLA all psychedelics will have a reduced effect.
 ===Dangerous interactions===