Banisteriopsis caapi: Difference between revisions

>David Hedlund
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#REDIRECT [[Harmala alkaloid#Banisteriopsis caapi]]
{{for|the [[DMT]]/[[MAOI]] plant brew that shares the same name as this plant|ayahuasca}}
 
{{BotanyBox/Banisteriopsis caapi}}
 
'''''Banisteriopsis caapi''''', also known as '''ayahuasca''', '''caapi''' or '''yagé''', is a South American liana of the family Malpighiaceae. It is used to prepare [[ayahuasca]], a decoction with a long history of its [[entheogen]]ic use and its status as a "plant teacher" among the indigenous peoples of the Amazon rainforest.
 
==History and culture==
 
===Research===
The alkaloids of ''Banisteriopsis caapi'', the plant source of the Amazonian hallucinogen [[ayahuasca]], stimulate adult neurogenesis ''in vitro''.<ref>https://www.nature.com/articles/s41598-017-05407-9</ref>
 
==Chemistry==
Banisteriopsis caapi (also known as ayahuasca, caapi or yajé) is a South American jungle vine of the family Malpighiaceae. It contains harmine, harmaline, and tetrahydroharmine in the following proportions:
*'''Harmine:''' 0.31-8.43%
*'''Harmaline:''' 0.03-0.83%
* '''Proanthocyanidins''' (less known MAOIs)
** '''(−)-epicatechin'''
** '''(−)-procyanidins'''
*'''Tetrahydroharmine:''' 0.05-2.94%
 
==Toxicity and harm potential==
 
===Dangerous interactions===
 
====Cholinergics====
[[Cholinergic]] substances combined with ''Banisteriopsis caapi'' can cause a [https://en.wikipedia.org/wiki/Cholinergic_crisis cholinergic crisis] because the plant contains acetylcholinesterase inhibitors (AChEIs):
* Harmaline<ref name="Pubmed-19784581">https://www.ncbi.nlm.nih.gov/pubmed/19784581</ref>
* Harmine<ref name="Pubmed-19784581" />
 
==See also==
*''[[Peganum harmala]]''
*[[Beta-Carbolines]]
*[[Psychedelics]]
*[[Tryptamines]]
*[[Phenethylamines]]
 
==External links==
** [https://en.wikipedia.org/wiki/Banisteriopsis_caapi ''Banisteriopsis caapi'' (Wikipedia)]
** [https://erowid.org/plants/banisteriopsis/banisteriopsis.shtml ''Banisteriopsis caapi'' (Erowid Vault)]
* Harmala alkaloids
** [http://en.wikipedia.org/wiki/Harmala_alkaloid Harmala alkaloids (Wikipedia)]
*** [https://en.wikipedia.org/wiki/Harmaline Harmaline (Wikipedia)]
*** [https://en.wikipedia.org/wiki/Harmine Harmine (Wikipedia)]
*** [https://en.wikipedia.org/wiki/Tetrahydroharmine Tetrahydroharmine (Wikipedia)]
** [https://erowid.org/chemicals/harmala/harmala.shtml Harmala Alkaloids (Erowid Vault)]
** [https://isomerdesign.com/PiHKAL/read.php?domain=tk&id=13 Harmaline (TiHKAL / Isomer Design)]
** [https://isomerdesign.com/PiHKAL/read.php?domain=tk&id=14 Harmine (TiHKAL / Isomer Design)]
** [https://isomerdesign.com/PiHKAL/read.php?domain=tk&id=54 Tetrahydroharmine (TiHKAL / Isomer Design)]
 
==Literature==
* Morales-García, J. A., de la Fuente Revenga, M., Alonso-Gil, S., Rodríguez-Franco, M. I., Feilding, A., Perez-Castillo, A., & Riba, J. (2017). The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro. Scientific Reports, 7(1), 5309. https://doi.org/10.1038/s41598-017-05407-9
 
==References==
<references/>
[[Category:Acetylcholinesterase inhibitor]]
[[Category:beta-Carboline]]
[[Category:Entheogen]]
[[Category:MAOI]]
[[Category:Neurogenesis inducer]]
[[Category:Psychoactive substance]]