GHB: Difference between revisions

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|}'''GHB''', also known as '''γ-Hydroxybutyric acid''' and '''4-hydroxybutanoic acid''', is a naturally occurring substance with [[depressant]] effects which is found in the human central nervous system, as well as in wine, beef, small citrus fruits, and in small amounts in almost all animals.<ref>Weil, Andrew; Winifred Rosen (1993). "Depressants". From Chocolate to Morphine (2nd ed.). Boston/New York: Houghton Mifflin Company. p. 77. ISBN 0-395-66079-3.</ref>  
|}'''GHB''', also known as '''γ-Hydroxybutyric acid''' and '''4-hydroxybutanoic acid''', is a naturally occurring substance with [[depressant]] effects which is found in the human central nervous system, as well as in wine, beef, small citrus fruits, and in small amounts in almost all animals.<ref>Weil, Andrew; Winifred Rosen (1993). "Depressants". From Chocolate to Morphine (2nd ed.). Boston/New York: Houghton Mifflin Company. p. 77. ISBN 0-395-66079-3.</ref>  


GHB as the sodium salt, known as sodium oxybate (INN) or by the trade name Xyrem,<ref>http://www.reuters.com/finance/stocks/companyProfile?rpc=66&symbol=JAZZ.O</ref> is used to treat cataplexy<ref>Sodium Oxybate | http://www.nlm.nih.gov/medlineplus/druginfo/meds/a605032.html</ref> and excessive daytime sleepiness in patients with narcolepsy. It has also been used in a medical setting as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance.[5] It is also used as an intoxicant (illegally in many jurisdictions) or as a date rape drug.<ref>GHB, GBL and 1,4BD as Date Rape Drugs | http://web.archive.org/web/20120510151441/http://www.justice.gov/dea//ongoing/daterapep.html</ref>  
GHB as the sodium salt, known as sodium oxybate (INN) or by the trade name Xyrem,<ref>http://www.reuters.com/finance/stocks/companyProfile?rpc=66&symbol=JAZZ.O</ref> is used to treat cataplexy<ref>Sodium Oxybate | http://www.nlm.nih.gov/medlineplus/druginfo/meds/a605032.html</ref> and excessive daytime sleepiness in patients with narcolepsy. It has also been used in a medical setting as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. It is also used as an intoxicant (illegally in many jurisdictions) or as a date rape drug.<ref>GHB, GBL and 1,4BD as Date Rape Drugs | http://web.archive.org/web/20120510151441/http://www.justice.gov/dea//ongoing/daterapep.html</ref>  


GHB is naturally produced in the human body's cells. As a supplement or drug, it is used most commonly in the form of a salt. GHB is also produced as a result of fermentation, and so is found in small quantities in some beers and wines. Succinic semialdehyde dehydrogenase deficiency is a disease that causes GHB to accumulate in the blood.
GHB is naturally produced in the human body's cells. As a supplement or drug, it is used most commonly in the form of a salt. GHB is also produced as a result of fermentation, and so is found in small quantities in some beers and wines. Succinic semialdehyde dehydrogenase deficiency is a disease that causes GHB to accumulate in the blood.
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