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MiPLA: Difference between revisions

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m Kenan moved page MiPLA to Talk:MiPLA over a redirect without leaving a redirect: I'd like to have more headstart for chris to check the pharmacology section!
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Expanded and cleaned up article. Ready for publication.
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{{SubstanceBox/MiPLA}}
{{SubstanceBox/MiPLA}}


'''N-Methyl-N-isopropyllysergamide''' (also known as '''methylisopropyllysergamide''', '''Lamide''' and '''MiPLA''') is a novel [[psychoactive class::psychedelic]] substance of the [[chemical class::lysergamide]] class. MiPLA is chemically similar to LSD and has a similar mechanism of action, working primarily by stimulating [[serotonin]] [[receptors]] in the brain.
'''N-Methyl-N-isopropyllysergamide''' (also known as '''methylisopropyllysergamide''', '''Lamide''' and '''MIPLA''') is a novel [[psychoactive class::psychedelic]] substance of the [[chemical class::lysergamide]] class. MIPLA is chemically similar to LSD and has a similar mechanism of action, working primarily by binding to the [[serotonin]]-2A [[receptor]] in the brain.{{citation needed}}


MiPLA was first discovered by Albert Hoffman as a part of the original structure-activity research for [[LSD]]. It has recently been researched in greater detail by by a team led by David E. Nichols at Purdue University. MiPLA and its effects are also mentioned in Alexander Shulgin's "Pharmacology Notes #9" and "Pharmacology Notes C".<ref>https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebook9_searchable.pdf</ref><ref>https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebookc_searchable.pdf</ref> According to Shulgin, human subjects administered MIPLA at doses of 180–300μg experienced LSD-like psychedelic effects, making it about two- to threefold less potent than LSD.<ref>Halberstadt, A.L., Klein, L.M., Chatha, M. et al. Psychopharmacology (2018). http://dx.doi.org/10.1007/s00213-018-5055-9</ref>
MIPLA was first discovered by Albert Hoffman as a part of the original structure-activity research for [[LSD]]. It has recently been researched in greater detail by by a team led by David E. Nichols at Purdue University. MIPLA and its effects are also mentioned in Alexander Shulgin's "Pharmacology Notes #9" and "Pharmacology Notes C".<ref>https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebook9_searchable.pdf</ref><ref>https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebookc_searchable.pdf</ref> According to Shulgin, human subjects administered MIPLA at doses of 180–300 μg experienced LSD-like psychedelic effects, making it about two- to threefold less potent than LSD.<ref>Halberstadt, A.L., Klein, L.M., Chatha, M. et al. Psychopharmacology (2018). http://dx.doi.org/10.1007/s00213-018-5055-9</ref>


User reports describe the effects of MiPLA as similar to those of LSD, with some marked differences. It is described as being more mentally and physically oriented but with a less introspective headspace and subtle, albeit pronounced visuals. It also has a notably shorter duration at 4-6 hours and is generally described as less anxiety-provoking than other lysergamides. Reports of users taking up to 600ug doses have indicated that higher doses of MiPLA don't change the experience very much if at all, whether visually, mentally, or physically.
User reports describe the effects of MIPLA as similar to those of LSD, with some notable differences. MIPLA has been described as being more mentally and physically oriented but with a less introspective headspace accompanied by subtle visuals. It also has a notably shorter duration at 4-6 hours and is generally described as less anxiety-provoking than LSD and other lysergamides.  


Very little data exists about the pharmacological properties, metabolism, and toxicity of MiPLA. It is highly advised to use harm reduction practices when using this substance.
Very little data exists about the pharmacological properties, metabolism, and toxicity of MIPLA. It is highly advised to use harm reduction practices when using this substance.


==Chemistry==
==Chemistry==
The chemical name of MiPLA is methylisopropyllysergamide. MiPLA belongs to a class of organic compounds known as lysergamides, which are a subclass of ergolines (derivatives of the alkaloids found in the ergot fungus). The most prominent member of the lysergamides is [[LSD]], lysergic acid diethylamide.
The chemical name of MIPLA is methylisopropyllysergamide. MIPLA belongs to a class of organic compounds known as lysergamides, which are a subclass of ergolines (derivatives of the alkaloids found in the ergot fungus). The most prominent member of the lysergamides is [[LSD]], lysergic acid diethylamide.


MiPLA is a structural isomer of LSD. Like LSD, the chemical structure of MiPLA is based on the lysergic acid amide structural skeleton. However, whereas LSD has two ethyl groups bound to the amide nitrogen, MiPLA is substituted with a methyl and isopropyl group.
MIPLA is a structural isomer of LSD. Like LSD, the chemical structure of MIPLA is based on the lysergic acid amide structural skeleton. However, whereas LSD has two ethyl groups bound to the amide nitrogen, MIPLA is substituted with a methyl and isopropyl group.


MiPLA is a chiral compound with two stereocenters at R5 and R8. The differences in psychoactivity between the stereoisomers have not been investigated.
MIPLA is a chiral compound with two stereocenters at R5 and R8. The differences in psychoactivity between the stereoisomers have not been investigated.


==Pharmacology==
==Pharmacology==
As with its structurally related Lysergamides, MiPLA principally acts as a 5-HT2A partial agonist, through which it exerts its psychedelic effects.
As with its structurally related lysergamides, MIPLA principally acts as a 5-HT2A partial agonist, through which it exerts its psychedelic effects. However, the role of these interactions and how they result in the psychedelic experience is unclear.


However, the role of these interactions and how they result in the psychedelic experience continues to remain an object of scientific elucidation.
Owing to similarities in chemical structure, MIPLA and LSD have highly similar binding profiles at monoamine receptors (i.e. [[serotonin]], [[dopamine]], and [[norepinephrine]]).{{citation needed}}


Owing to similarities in chemical structure, MIPLA and LSD have highly similar binding profiles at monoamine receptors.
One study found MIPLA to fully substitute for LSD in rats, with about half the potency of the training drug.{{citation needed}}
 
One study found MIPLA to fully substitute for LSDin rats, with about half the potency of the training drug


==Subjective effects==
==Subjective effects==
{{EffectStub}}
{{EffectStub}}
MiPLA is commonly reported to be significantly shorter in its duration and less uncomfortable in both its [[Uncomfortable_physical_effects|negative physical side effects]] and general [[anxiety]].
MIPLA is commonly reported to be significantly shorter in its duration and less uncomfortable in both its [[Uncomfortable_physical_effects|negative physical side effects]] and general [[anxiety]].


{{Preamble/SubjectiveEffects}}
{{Preamble/SubjectiveEffects}}
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|{{effects/physical|
|{{effects/physical|


*'''[[Effect::Stimulation]]''' - MiPLA is considered to be primarily stimulating in nature in the same vein as LSD. This is in distinction to other, more commonly used psychedelics such as [[psilocybin]] which are more consistent in producing [[sedation]] and [[muscle relaxation|relaxedness]].
*'''[[Effect::Stimulation]]''' - MIPLA is considered to be primarily stimulating in nature in the same vein as LSD. This is in distinction to other, more commonly used psychedelics such as [[psilocybin]] which are more consistent in producing [[sedation]] and [[muscle relaxation|relaxedness]].
*'''[[Effect::Spontaneous bodily sensations]]''' - The "body high" of MiPLA can be described as proportionally intense in comparison to its accompanying visual and cognitive effects. It behaves as a euphoric, fast-moving, sharp and location specific tingling sensation. For some, it is manifested spontaneously at different unpredictable points throughout the experience, but for most it maintains a steady presence that rises with the onset and hits its limit once the peak has been reached. In comparison to LSD, it is a little less sharp in the tingling sensations it produces as but is otherwise essentially indistinguishable.
*'''[[Effect::Spontaneous bodily sensations]]''' - The "body high" of MIPLA can be described as proportionally intense in comparison to its accompanying visual and cognitive effects. It behaves as a pleasurable, fast-moving, sharp and location specific tingling sensation. For some, it is manifested spontaneously at different unpredictable points throughout the experience, but for most it maintains a steady presence that rises with the onset and hits its limit once the peak has been reached. In comparison to LSD, MIPLA is a little less sharp in the tingling sensations it produces as but is otherwise essentially indistinguishable.
*'''[[Effect::Physical euphoria]]''' - It should be noted that this effect is not as reliably induceable as it is with substances like [[stimulants]] or [[entactogens]], and can just as easily manifest as physical discomfort without any apparent reason.  
*'''[[Effect::Physical euphoria]]''' - Physical euphoria on MIPLA is not as consistent as it is with substances like [[stimulants]] or [[entactogens]], and can just as easily manifest as physical discomfort without any apparent reason.  
*'''[[Effect::Changes in felt bodily form]]''' - This effect is often accompanied by a sense of warmth or [[Unity and interconnectedness#Unity between the self and specific external systems|unity]] and usually occurs during and up to the peak of the experience or directly afterward. Users can feel as if they are physically part of or conjoined with other objects. This is usually reported as feeling comfortable and peaceful in its sensations.   
*'''[[Effect::Changes in felt bodily form]]''' - This effect is often accompanied by a sense of warmth or [[Unity and interconnectedness#Unity between the self and specific external systems|unity]] and usually occurs during and up to the peak of the experience or directly afterward. Users can feel as if they are physically part of or conjoined with other objects. This is usually reported as feeling comfortable and peaceful in its sensations.   
*'''[[Effect::Tactile enhancement]]''' - Feelings of enhanced tactile sensations are consistently present at moderate levels throughout most MiPLA trips.
*'''[[Effect::Tactile enhancement]]''' - Feelings of enhanced tactile sensations are consistently present at moderate levels throughout most MIPLA trips.
*'''[[Effect::Temperature regulation suppression]]'''{{citation needed}}
*'''[[Effect::Temperature regulation suppression]]'''{{citation needed}}
*'''[[Effect::Increased bodily temperature]]'''{{citation needed}}
*'''[[Effect::Increased bodily temperature]]'''{{citation needed}}
*'''[[Effect::Nausea]]'''
*'''[[Effect::Nausea]]'''
*'''[[Effect::Stamina enhancement]]''' - This is generally mild in comparison to traditional [[stimulants]].
*'''[[Effect::Stamina enhancement]]''' - Generally mild in comparison to traditional [[stimulants]].
*'''[[Effect::Bodily control enhancement]]'''
*'''[[Effect::Bodily control enhancement]]'''
*'''[[Effect::Appetite suppression]]'''
*'''[[Effect::Appetite suppression]]'''
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====[[Geometry]]====
====[[Geometry]]====
The [[visual geometry]] evoked by MiPLA can be described as more similar in appearance to that of [[LSD]], [[2C-B]] or [[4-HO-MET]] than [[psilocin]], [[LSA]] or [[DMT]]. It can be comprehensively described through its [[Visual_effects:_Geometry#Variations|variations]] as primarily intricate in complexity, algorithmic in form, unstructured in organization, brightly lit, colourful and cartoonish in scheme, organic in feel, flat in shading, soft in its edges, large in size, slow in speed, smooth in motion, either angular or round in its corners, non-immersive in-depth and consistent in intensity. At higher dosages, it consistently results in states of [[Effect::Level 8B]] visual geometry over [[Level 8A]].
The [[visual geometry]] evoked by MIPLA can be described as more similar in appearance to that of [[LSD]], [[2C-B]] or [[4-HO-MET]] than [[psilocin]], [[LSA]] or [[DMT]]. It can be comprehensively described through its [[Visual_effects:_Geometry#Variations|variations]] as primarily intricate in complexity, algorithmic in form, unstructured in organization, brightly lit, colourful and cartoonish in scheme, organic in feel, flat in shading, soft in its edges, large in size, slow in speed, smooth in motion, either angular or round in its corners, non-immersive in-depth and consistent in intensity. At higher dosages, it consistently results in states of [[Effect::Level 8B]] visual geometry over [[Level 8A]].


In comparison to LSD specifically, MiPLA's geometry tends to be more rounded in its corners, slightly softer in its edges, warmer in hue, and slightly less intricate in its form. Aside from this, it is otherwise identical in its appearance.
In comparison to LSD specifically, MIPLA's geometry tends to be more rounded in its corners, slightly softer in its edges, warmer in hue, and slightly less intricate in its form. Aside from this, it is otherwise identical in its appearance.


====Hallucinatory states====
====Hallucinatory states====
MiPLA is capable of producing a full range of low and high level hallucinatory states in a fashion that is a less consistent and reproducible than that of many other commonly used psychedelics such as [[psilocin]] or [[DMT]] but considerably more likely to when compared to that of [[LSD]]. This can feel similar to the hallucinations which occur with [[4-AcO-DMT]] but tends to occur almost exclusively at [[heavy|heavier]] [[dosage|doses]]. Some of these effects include:
MIPLA is capable of producing a full range of low and high level hallucinatory states in a fashion that is a less consistent and reproducible than that of many other commonly used psychedelics such as [[psilocin]] or [[DMT]] but considerably more likely to when compared to that of [[LSD]]. This can feel similar to the hallucinations which occur with [[4-AcO-DMT]] but tends to occur almost exclusively at [[heavy|heavier]] [[dosage|doses]]. Some of these effects include:


*'''[[Effect::Machinescapes]]'''
*'''[[Effect::Machinescapes]]'''
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*'''[[Effect::Analysis enhancement]]''' - This effect is consistent in its manifestation and [[outrospection]] dominant.
*'''[[Effect::Analysis enhancement]]''' - This effect is consistent in its manifestation and [[outrospection]] dominant.
*'''[[Effect::Conceptual thinking]]'''
*'''[[Effect::Conceptual thinking]]'''
*'''[[Effect::Cognitive euphoria]]''' - This component is, generally speaking less consistent and pronounced than it is with substances like [[psilocybin]] and [[MDMA]]. The mental euphoria experienced on MiPLA is usually simply due to an enhancement of the user’s current psychological and emotional state coupled with its more regularly occurring effect, [[physical euphoria]].
*'''[[Effect::Cognitive euphoria]]'''
*'''[[Effect::Novelty enhancement]]'''
*'''[[Effect::Novelty enhancement]]'''
*'''[[Effect::Immersion enhancement]]'''
*'''[[Effect::Immersion enhancement]]'''
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===Experience reports===
===Experience reports===
Anecdotal reports which describe the effects of this compound within our [[experience index]] include:
Anecdotal reports which describe the effects of this compound within our [[experience index]] include:
{{#ask: [[Category:MiPLA]][[Category:Experience]]|format=ul|Columns=1}}
{{#ask: [[Category:MIPLA]][[Category:Experience]]|format=ul|Columns=1}}
Additional experience reports can be found here:
Additional experience reports can be found here:
* [https://erowid.org/experiences/subs/exp_MIPLA.shtml Erowid Experience Vaults: MiPLA]
* [https://erowid.org/experiences/subs/exp_MIPLA.shtml Erowid Experience Vaults: MIPLA]


==Toxicity and harm potential==
==Toxicity and harm potential==
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
The toxicity and long-term health effects of recreational MiPLA use has not been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because MiPLA is a [[research chemical]] with very little history of human usage.  
The toxicity and long-term health effects of recreational MIPLA use has not been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because MIPLA is a [[research chemical]] with very little history of human usage.  


The body of anecdotal reports suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption.  
The body of anecdotal reports suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption.  


As with other psychedelic substances, there are relatively few physical side effects that have been reported associated with acute MiPLA exposure. Although no formal studies have been conducted, it is likely that as with [[LSD]] itself, MiPLA is able to be considered non-addictive, with an [[Toxicity::extremely low toxicity]] relative to dose.<ref>Passie, T., Halpern, J. H., Stichtenoth, D. O., Emrich, H. M., & Hintzen, A. (2008). [http://www.maps.org/w3pb/new/2008/2008_Passie_23067_1.pdf The Pharmacology of Lysergic Acid Diethylamide: A Review], 14, 295–314. https://doi.org/10.1111/j.1755-5949.2008.00059.x</ref> It is also likely that as with LSD, there are little to no negative physical, cognitive, psychiatric or other toxic consequences associated with acute MiPLA exposure. 
However, as is the case for LSD, it is possible that MIPLA can act as a potential trigger for those with underlying psychiatric conditions. Those with a personal or family history of mental illness are generally advised not to use this substance, particularly outside of a supervised medical setting.  
 
However, as is the case for LSD, it is possible that MiPLA can act as a potential trigger for those with underlying psychiatric conditions. Those with a personal or family history of mental illness are generally advised not to use this substance, particularly outside of a supervised medical setting.  


It is strongly recommended that one uses [[responsible drug use|harm reduction practices]] when using this substance.
It is strongly recommended that one uses [[responsible drug use|harm reduction practices]] when using this substance.


===Overdose===
===Overdose===
The LD<sub>50</sub> of MiPLA is unknown. Adverse psychological reactions may be more likely to occur at higher doses. Some of these include [[anxiety]], [[delusions]], [[panic attacks]] and more rarely [[seizures]]. Medical attention is usually only needed if suspected of severe psychotic episodes or “fake acid” (such as [[25i-NBOMe]] or [[DOB]]). Administration of [[benzodiazepines]] or [[antipsychotics]] can help to relieve the negative cognitive effects of MiPLA.
The LD<sub>50</sub> of MIPLA is unknown. Adverse psychological reactions may be more likely to occur at higher doses. Some of these include [[anxiety]], [[delusions]], [[panic attacks]] and more rarely [[seizures]]. Medical attention is usually only needed if suspected of severe psychotic episodes or “fake acid” (such as [[25i-NBOMe]] or [[DOB]]). Administration of [[benzodiazepines]] or [[antipsychotics]] can help to relieve the negative cognitive effects of MIPLA.


===Dependence and abuse potential===
===Dependence and abuse potential===
Although no formal studies have been conducted, it is not unreasonable to assume that as with LSD itself, MiPLA is [[Addiction potential::not habit-forming]] and that the desire to use it can actually decrease with use.
Although no formal studies have been conducted, it is not unreasonable to assume that as with LSD itself, MIPLA is [[Addiction potential::not habit-forming]] and that the desire to use it can actually decrease with use.


Tolerance to the effects of MiPLA are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::5-7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::14 days]] to be back at baseline (in the absence of further consumption). MiPLA presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the use of MiPLA all psychedelics will have a reduced effect.
Tolerance to the effects of MIPLA are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::5-7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::14 days]] to be back at baseline (in the absence of further consumption). MIPLA presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the use of MIPLA all psychedelics will have a reduced effect.


Owing to its activity at the 5-HT<sub>2A</sub> receptor, MiPLA presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of MiPLA all psychedelics will have a reduced effect.
Owing to its activity at the 5-HT<sub>2A</sub> receptor, MIPLA presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of MIPLA all psychedelics will have a reduced effect.


===Dangerous interactions===
===Dangerous interactions===
{{DangerousInteractions/Intro}}
{{DangerousInteractions/Intro}}


*'''[[Tramadol]]''' - Tramadol lowers the seizure threshold<ref>Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology, 5(2), 63-67. doi:10.1007/BF03161089</ref> and [[psychedelics]] may act as triggers for seizures, particularly in predisposed individuals.{{citation needed}}
*'''[[UnsafeInteraction::Lithium]]''' - Individuals who take lithium for bipolar disorder or other psychiatric conditions should not take MIPLA. There are numerous anecdotal reports of individuals experiencing seizures and/or psychosis from the combination of LSD and lithium.<ref>https://erowid.org/chemicals/lsd/lsd_interactions.shtml | LSD Interactions by Erowid</ref><ref>Wanderli. [https://erowid.org/experiences/exp.php?ID=83935 "A Nice Little Trip to the Hospital: An Experience with Lithium & LSD (ID 83935)"]. Erowid.org. Oct 3, 2010.</ref><ref>MissDja1a. [https://erowid.org/experiences/exp.php?ID=75153 "Having a Seizure and Passing Out: An Experience with Lithium & LSD (ID 75153)"]. Erowid.org. Dec 16, 2008. </ref><ref>Reddit account of seizure on LSD + Lithium | https://www.reddit.com/r/Psychonaut/comments/17uspp/please_read_a_cautionary_tale_concerning_lsd/</ref> Due to MIPLA's chemical similarity to LSD, it is assumed to carry a similar risk.
*'''[[Stimulants]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis.{{citation needed}}
*'''[[UnsafeInteraction::Tramadol]]''' - Tramadol lowers the seizure threshold<ref>Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology, 5(2), 63-67. doi:10.1007/BF03161089</ref> and [[psychedelics]] may act as triggers for seizures, particularly in predisposed individuals.{{citation needed}}
*'''[https://en.wikipedia.org/wiki/Lithium_(medication) Lithium]''' - Lithium is often used as treatment for bipolar disorder. It may possibly cause elevated risk of seizures and psychosis due to its [[Glutamate|glutaminergic]] and [[GABA|GABAergic]] effects.{{citation needed}}
*'''[[UncertainInteraction::Stimulants]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis.{{citation needed}}


==Legal status==
==Legal status==
{{legalStub}}
{{legalStub}}
MiPLA currently exists in a legal grey area in most parts of the world. This means that it is not specifically illegal within most countries but individuals may still be charged for its possession under certain circumstances such as under analog laws and with the intent to sell or consume.  
MIPLA currently exists in a legal grey area in most parts of the world. This means that it is not specifically illegal within most countries but individuals may still be charged for its possession under certain circumstances such as under analog laws and with the intent to sell or consume.  
*'''Austria:''' MiPLA is technically not illegal but it may fall in the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich) as an analogue of LSD. {{citation needed}}
*'''Austria:''' MIPLA is technically not illegal but it may fall in the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich) as an analogue of LSD. {{citation needed}}
*'''United States:''' MiPLA is not scheduled but may be considered to be an analogue of LSD, which would make it illegal to possess for human consumption under the Federal Analogue Act.
*'''United States:''' MIPLA is not scheduled but may be considered to be an analogue of LSD, which would make it illegal to possess for human consumption under the Federal Analogue Act.


==See also==
==See also==
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==External links==
==External links==
* [https://en.wikipedia.org/wiki/Methylisopropyllysergamide MiPLA (Wikipedia)]
* [https://en.wikipedia.org/wiki/Methylisopropyllysergamide MIPLA (Wikipedia)]
* [https://isomerdesign.com/PiHKAL/explore.php?domain=tk&id=5327 MiPLA (TiHKAL / Isomer Design)]
* [https://isomerdesign.com/PiHKAL/explore.php?domain=tk&id=5327 MIPLA (TiHKAL / Isomer Design)]


===Discussion===
===Discussion===
* [http://www.bluelight.org/vb/threads/784440-The-Small-amp-Handy-MIPLA-(Methylisopropyllysergamide)-Thread The Small & Handy MiPLA Thread (Bluelight)]
* [http://www.bluelight.org/vb/threads/784440-The-Small-amp-Handy-MIPLA-(Methylisopropyllysergamide)-Thread The Small & Handy MIPLA Thread (Bluelight)]


==Literature==
==Literature==
Retrieved from "http://psy.st/wiki/MiPLA"