4-AcO-DMT: Difference between revisions

Line 6:

The synthesis of 4-AcO-DMT was first reported in 1963 by [[Albert Hofmann]] and Franz Troxler.<ref>http://worldwide.espacenet.com/textdoc?DB=EPODOC&IDX=US3075992</ref><ref>http://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=3075992&KC=&FT=E&locale=en_EP</ref> However, further studies were not carried out. A 1999 paper by [[David E. Nichols]] suggested it as a useful alternative to psilocybin for pharmacological research.<ref>Nichols, D. E., & Frescas, S. (1999). Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin. Synthesis, 1999(6), 935-938. </ref> Reports of human use began to surface following its appearance on the online [[research chemical]] market in the 2010s.

~~User reports indicate~~ that the subjective effects of 4-AcO-DMT are extremely similar to those of [[psilocybin mushrooms]]. Like psilocybin, 4-AcO-DMT is theorized to act as a [[prodrug]] to [[psilocin]], which may account for this similarity. Notable effects include [[geometry|geometric visual hallucinations]], [[time distortion]], [[introspection|enhanced introspection]], and [[ego loss]]. Its classical psychedelic effects and favorable tolerability has led it to become popular among novel psychoactive substance users, particularly those seeking [[entheogenic]] experiences.

Users report that the subjective effects of 4-AcO-DMT are extremely similar to those of [[psilocybin mushrooms]]. Like psilocybin, 4-AcO-DMT is theorized to act as a [[prodrug]] to [[psilocin]], which may account for this similarity. Notable effects include [[geometry|geometric visual hallucinations]], [[time distortion]], [[introspection|enhanced introspection]], and [[ego loss]]. Its classical psychedelic effects and favorable tolerability has led it to become popular among novel psychoactive substance users, particularly those seeking [[entheogenic]] experiences.

Very little data exists on the pharmacology, metabolism, and toxicity of 4-AcO-DMT. Like other psychedelics, it is assumed to be non-toxic and non-addictive (although there is no evidence to support this). It is highly advised to use [[harm reduction practices]] if using this substance.

@@ Line 6: / Line 6: @@
 The synthesis of 4-AcO-DMT was first reported in 1963 by [[Albert Hofmann]] and Franz Troxler.<ref>http://worldwide.espacenet.com/textdoc?DB=EPODOC&IDX=US3075992</ref><ref>http://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=3075992&KC=&FT=E&locale=en_EP</ref> However, further studies were not carried out. A 1999 paper by [[David E. Nichols]] suggested it as a useful alternative to psilocybin for pharmacological research.<ref>Nichols, D. E., & Frescas, S. (1999). Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin. Synthesis, 1999(6), 935-938. </ref> Reports of human use began to surface following its appearance on the online [[research chemical]] market in the 2010s.
-User reports indicate that the subjective effects of 4-AcO-DMT are extremely similar to those of [[psilocybin mushrooms]]. Like psilocybin, 4-AcO-DMT is theorized to act as a [[prodrug]] to [[psilocin]], which may account for this similarity. Notable effects include [[geometry|geometric visual hallucinations]], [[time distortion]], [[introspection|enhanced introspection]], and [[ego loss]]. Its classical psychedelic effects and favorable tolerability has led it to become popular among novel psychoactive substance users, particularly those seeking [[entheogenic]] experiences.
+Users report that the subjective effects of 4-AcO-DMT are extremely similar to those of [[psilocybin mushrooms]]. Like psilocybin, 4-AcO-DMT is theorized to act as a [[prodrug]] to [[psilocin]], which may account for this similarity. Notable effects include [[geometry|geometric visual hallucinations]], [[time distortion]], [[introspection|enhanced introspection]], and [[ego loss]]. Its classical psychedelic effects and favorable tolerability has led it to become popular among novel psychoactive substance users, particularly those seeking [[entheogenic]] experiences.
 Very little data exists on the pharmacology, metabolism, and toxicity of 4-AcO-DMT. Like other psychedelics, it is assumed to be non-toxic and non-addictive (although there is no evidence to support this). It is highly advised to use [[harm reduction practices]] if using this substance.