DOC: Difference between revisions

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DOC was first synthesized by a team at the University of Alberta in 1972.<ref>Coutts, Ronald T; Malicky, Jerry L. (1973). "The Synthesis of Some Analogs of the Hallucinogen 1-(2,5-Dimethoxy-4-methylphenyl)-2-aminopropane (DOM)". Canadian Journal of Chemistry, 1973, 51(9): 1402-1409, 10.1139/v73-210 | http://www.nrcresearchpress.com/doi/abs/10.1139/v73-210</ref> However, its usage in humans was not popularized until the 1991 publication [[PiHKAL]] ("Phenethylamines I Have Known And Loved") by [[Alexander Shulgin]].<ref name="PiHKAL">http://www.erowid.org/library/books_online/pihkal/pihkal.shtml</ref> Preceding this, a 1989 forensic analysis of designer amphetamine samples identified DOC in Canadian drug seizures.<ref>Brian A. Dawson & George A. Neville (1989) "Identification of Two New 'Designer' Amphetamines by NMR Techniques", Canadian Society of Forensic Science Journal, 22:2, 195-202, https://doi.org/10.1080/00085030.198</ref>

Over the years DOC has come to be known as a highly dose-sensitive psychedelic that is often sold in powder form or on blotting paper and known for its long duration (over 12-24 hours), strong visual effects, a unique form of [[stimulation]], and a significant [[body load]].

Over the years DOC has come to be known as a highly dose-sensitive psychedelic that is often sold in powder form or on blotting paper and known for its long duration (over 12-24 hours), strong visual effects, a unique form of [[stimulation]], and a significant body load.

Today, DOC is used as a [[recreational drug use|recreational drug]] and an [[entheogen]], rarely sold on the streets (unless in the form of misrepresented [[LSD]]) and almost exclusively obtained as a grey area [[research chemical]] through online vendors.

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|{{effects/physical|

*'''[[Effect::Stimulation]]''' - DOC is usually reported to be extremely stimulating at levels which are capable of becoming uncomfortable and overwhelming (although to a lesser extent than other [[DOx]] compounds such as [[DOI]] and [[DOB]]). This can result in a shakiness and unsteadiness of the hands but encouraging one to move around, run, dance, climb and generally engage in physical activities. In comparison, other more commonly used psychedelics such as [[psilocin]] are generally sedating and relaxed. However, at ~~higher~~ doses the stimulation becomes less apparent as the strong psychedelic effects take over.

*'''[[Effect::Stimulation]]''' - DOC is usually reported to be extremely stimulating at levels which are capable of becoming uncomfortable and overwhelming (although to a lesser extent than other [[DOx]] compounds such as [[DOI]] and [[DOB]]). This can result in a shakiness and unsteadiness of the hands but encouraging one to move around, run, dance, climb and generally engage in physical activities. In comparison, other more commonly used psychedelics such as [[psilocin]] are generally sedating and relaxed. However, at high enough doses the stimulation becomes less apparent as the strong psychedelic effects take over.

*'''[[Effect::Spontaneous physical sensations]]''' - The "body high" of DOC is manifested as somewhat intense in comparison to most classical psychedelics such as [[LSD]]. The sensation itself can be described as a constantly present yet somewhat mild energetic pins and needles sensation that encompasses a person’s entire body. It is usually felt over every square inch of the skin, but occasionally manifests itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.

**'''[[Effect::Physical euphoria]]''' - It should be noted that this effect is not as reliably induceable as it is with substances like stimulants or entactogens, and can just as easily manifest as physical discomfort without any apparent reason.

**'''[[Effect::Physical euphoria]]''' - It should be noted that this effect is not as reliably induceable as it is with substances like stimulants or entactogens, and can just as easily manifest as physical discomfort without any apparent reason. DOC and other psychedelic amphetamines tend to lean towards physical dysphoria more so than other psychedelics.

*'''[[Effect::Changes in felt bodily form]]''' - This effect is often accompanied by a sense of warmth, numbness or [[Unity and interconnectedness#Unity between the self and specific external systems|unity]] and usually occurs during and up to the peak of the experience or directly afterward. Users can feel as if they are physically part of or conjoined with other objects. This is usually reported as feeling comfortable in its sensations and even peaceful.

*'''[[Effect::Changes in felt bodily form]]'''

*'''[[Effect::Bodily control enhancement]]'''

*'''[[Effect::Tactile enhancement]]''' - Feelings of enhanced tactile sensation are consistently present at low to moderate levels throughout most DOC experiences.

*'''[[Effect::Nausea]]''' - Mild to extreme nausea is reported when consumed in moderate to high dosages and either passes once the person has vomited or gradually fades by itself as the peak sets in.

*'''[[Effect::Vasoconstriction]]''' - This effect is usually only present at higher dosages, but can be particularly uncomfortable when it manifests, and may persist throughout the main duration of the experience.

*'''[[Effect::Vasoconstriction]]''' - This effect is usually only present at higher dosages, but can be particularly uncomfortable when it manifests, and may persist throughout as well as after the main duration of the experience.

*'''[[Effect::Increased blood pressure]]'''

*'''[[Effect::Increased heart rate]]'''

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*'''[[Effect::Dehydration]]'''

*'''[[Effect::Dry mouth]]'''

*'''[[Effect::Bodily control enhancement]]'''

*'''[[Effect::Temperature regulation suppression]]''' - This effect is more prominent than it is with other psychedelics like [[LSD]].

*'''[[Effect::Temperature regulation suppression]]''' - This effect is more prominent than it is with [[LSD]].

*'''[[Effect::Diarrhea]]'''

*'''[[Effect::Teeth grinding]]'''

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{{effects/visual|

The visuals of DOC are commonly described as being very ~~digital~~ and linear, ~~yet not overly complex~~ in comparison to [[DOB]] or [[LSD]].

The visuals of DOC are commonly described as being very simplistic, cartoon-like and linear, in comparison to [[DOB]] or [[LSD]].

====Enhancements====

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[[Category:Psychoactive substance]]

[[Category:~~Phenethylamine~~]]

[[Category:Amphetamine]]

[[Category:Psychedelic]]

{{#set:Featured=true

@@ Line 6: / Line 6: @@
 DOC was first synthesized by a team at the University of Alberta in 1972.<ref>Coutts, Ronald T; Malicky, Jerry L. (1973). "The Synthesis of Some Analogs of the Hallucinogen 1-(2,5-Dimethoxy-4-methylphenyl)-2-aminopropane (DOM)". Canadian Journal of Chemistry, 1973, 51(9): 1402-1409, 10.1139/v73-210 | http://www.nrcresearchpress.com/doi/abs/10.1139/v73-210</ref> However, its usage in humans was not popularized until the 1991 publication [[PiHKAL]] ("Phenethylamines I Have Known And Loved") by [[Alexander Shulgin]].<ref name="PiHKAL">http://www.erowid.org/library/books_online/pihkal/pihkal.shtml</ref> Preceding this, a 1989 forensic analysis of designer amphetamine samples identified DOC in Canadian drug seizures.<ref>Brian A. Dawson & George A. Neville (1989) "Identification of Two New 'Designer' Amphetamines by NMR Techniques", Canadian Society of Forensic Science Journal, 22:2, 195-202, https://doi.org/10.1080/00085030.198</ref>
-Over the years DOC has come to be known as a highly dose-sensitive psychedelic that is often sold in powder form or on blotting paper and known for its long duration (over 12-24 hours), strong visual effects, a unique form of [[stimulation]], and a significant [[body load]].
+Over the years DOC has come to be known as a highly dose-sensitive psychedelic that is often sold in powder form or on blotting paper and known for its long duration (over 12-24 hours), strong visual effects, a unique form of [[stimulation]], and a significant body load.
 Today, DOC is used as a [[recreational drug use|recreational drug]] and an [[entheogen]], rarely sold on the streets (unless in the form of misrepresented [[LSD]]) and almost exclusively obtained as a grey area [[research chemical]] through online vendors.
@@ Line 29: / Line 29: @@
 |{{effects/physical|
-*'''[[Effect::Stimulation]]''' - DOC is usually reported to be extremely stimulating at levels which are capable of becoming uncomfortable and overwhelming (although to a lesser extent than other [[DOx]] compounds such as [[DOI]] and [[DOB]]). This can result in a shakiness and unsteadiness of the hands but encouraging one to move around, run, dance, climb and generally engage in physical activities. In comparison, other more commonly used psychedelics such as [[psilocin]] are generally sedating and relaxed. However, at higher doses the stimulation becomes less apparent as the strong psychedelic effects take over.
+*'''[[Effect::Stimulation]]''' - DOC is usually reported to be extremely stimulating at levels which are capable of becoming uncomfortable and overwhelming (although to a lesser extent than other [[DOx]] compounds such as [[DOI]] and [[DOB]]). This can result in a shakiness and unsteadiness of the hands but encouraging one to move around, run, dance, climb and generally engage in physical activities. In comparison, other more commonly used psychedelics such as [[psilocin]] are generally sedating and relaxed. However, at high enough doses the stimulation becomes less apparent as the strong psychedelic effects take over.
 *'''[[Effect::Spontaneous physical sensations]]''' - The "body high" of DOC is manifested as somewhat intense in comparison to most classical psychedelics such as [[LSD]]. The sensation itself can be described as a constantly present yet somewhat mild energetic pins and needles sensation that encompasses a person’s entire body. It is usually felt over every square inch of the skin, but occasionally manifests itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
-**'''[[Effect::Physical euphoria]]''' - It should be noted that this effect is not as reliably induceable as it is with substances like stimulants or entactogens, and can just as easily manifest as physical discomfort without any apparent reason.
+**'''[[Effect::Physical euphoria]]''' - It should be noted that this effect is not as reliably induceable as it is with substances like stimulants or entactogens, and can just as easily manifest as physical discomfort without any apparent reason. DOC and other psychedelic amphetamines tend to lean towards physical dysphoria more so than other psychedelics.
-*'''[[Effect::Changes in felt bodily form]]''' - This effect is often accompanied by a sense of warmth, numbness or [[Unity and interconnectedness#Unity between the self and specific external systems|unity]] and usually occurs during and up to the peak of the experience or directly afterward. Users can feel as if they are physically part of or conjoined with other objects. This is usually reported as feeling comfortable in its sensations and even peaceful.
+*'''[[Effect::Changes in felt bodily form]]'''
 *'''[[Effect::Bodily control enhancement]]'''
 *'''[[Effect::Tactile enhancement]]''' - Feelings of enhanced tactile sensation are consistently present at low to moderate levels throughout most DOC experiences.
 *'''[[Effect::Nausea]]''' - Mild to extreme nausea is reported when consumed in moderate to high dosages and either passes once the person has vomited or gradually fades by itself as the peak sets in.
-*'''[[Effect::Vasoconstriction]]''' - This effect is usually only present at higher dosages, but can be particularly uncomfortable when it manifests, and may persist throughout the main duration of the experience.
+*'''[[Effect::Vasoconstriction]]''' - This effect is usually only present at higher dosages, but can be particularly uncomfortable when it manifests, and may persist throughout as well as after the main duration of the experience.
 *'''[[Effect::Increased blood pressure]]'''
 *'''[[Effect::Increased heart rate]]'''
@@ Line 46: / Line 46: @@
 *'''[[Effect::Dehydration]]'''
 *'''[[Effect::Dry mouth]]'''
-*'''[[Effect::Bodily control enhancement]]'''
+*'''[[Effect::Temperature regulation suppression]]''' - This effect is more prominent than it is with other psychedelics like [[LSD]].
-*'''[[Effect::Temperature regulation suppression]]''' - This effect is more prominent than it is with [[LSD]].
 *'''[[Effect::Diarrhea]]'''
 *'''[[Effect::Teeth grinding]]'''
@@ Line 57: / Line 56: @@
 {{effects/visual|
-The visuals of DOC are commonly described as being very digital and linear, yet not overly complex in comparison to [[DOB]] or [[LSD]].
+The visuals of DOC are commonly described as being very simplistic, cartoon-like and linear, in comparison to [[DOB]] or [[LSD]].
 ====Enhancements====
@@ Line 190: / Line 189: @@
 [[Category:Psychoactive substance]]
-[[Category:Phenethylamine]]
+[[Category:Amphetamine]]
 [[Category:Psychedelic]]
 {{#set:Featured=true