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Opioids: Difference between revisions
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==Chemistry== | ==Chemistry== | ||
Opioids are based upon [[morphine]] and opium-like structures. They work via their similar chemical structures to the endogenous opioids in the body. Morphine derived opioids, known as morphinans, contain a benzene ring attached to two partially unsaturated cyclohexane rings (phenanthrene) and a 4th nitrogenous ring attached to the core at carbons 9 and 13. There are several classes of opioids which differ greatly in structure from each other. For example, [[fentanyl]] and its analogues are structurally unique from [[morphinans]] and [[tramadol]] | Opioids are based upon [[morphine]] and opium-like structures. They work via their similar chemical structures to the endogenous opioids in the body. Morphine derived opioids, known as morphinans, contain a benzene ring attached to two partially unsaturated cyclohexane rings (phenanthrene) and a 4th nitrogenous ring attached to the core at carbons 9 and 13. There are several classes of opioids which differ greatly in structure from each other. For example, [[fentanyl]] and its analogues are structurally unique from [[morphinans]] and [[tramadol]] derivatives. | ||
==Pharmacology== | ==Pharmacology== | ||