2C-T-2: Difference between revisions

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2C-T-2 was first synthesized and tested for activity in humans by [[Alexander Shulgin]] in 1981<ref>Shulgin, Alexander. "Pharmacology Lab Notes #4". Lafayette, CA. (1981-1982). p474 (Erowid.org) | https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebook4_searchable.pdf</ref> and described in his 1991 book [[PiHKAL]] ("Phenethylamines I Have Known and Loved").<ref name="pihkal2CT2">Shulgin, A., & Shulgin, A. (1991).

[http://isomerdesign.com/PiHKAL/read.php?id=33 IsomerDesign: "PiHKAL" - #33 - 2C-I]. Retrieved Jan 22, 2018.</ref> It is a member of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important [[phenethylamine]]-derived compounds, all of which except [[mescaline]] he developed and synthesized himself. They are found within the first book of [[PiHKAL]], and are as follows: [[~~Mescaline~~]], [[DOM]], [[2C-B]], 2C-E, [[2C-T-2]] and [[2C-T-7]].<ref name="pihkalweb">Shulgin, A., & Shulgin, A. (1991). [https://www.erowid.org/library/books_online/pihkal/pihkal.shtml Erowid Online Books: "PIHKAL" - The Chemical Story]. Retrieved April 14, 2017.</ref>

[http://isomerdesign.com/PiHKAL/read.php?id=33 IsomerDesign: "PiHKAL" - #33 - 2C-I]. Retrieved Jan 22, 2018.</ref> It is a member of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important [[phenethylamine]]-derived compounds, all of which except [[mescaline]] he developed and synthesized himself. They are found within the first book of [[PiHKAL]], and are as follows: [[mescaline]], [[DOM]], [[2C-B]], 2C-E, [[2C-T-2]] and [[2C-T-7]].<ref name="pihkalweb">Shulgin, A., & Shulgin, A. (1991). [https://www.erowid.org/library/books_online/pihkal/pihkal.shtml Erowid Online Books: "PIHKAL" - The Chemical Story]. Retrieved April 14, 2017.</ref>

Following the initial positive results found by Shulgin's research group, a more formal study was carried out by psychedelic psychotherapy pioneer Myron J. Stolaroff who was interested in evaluating the potential use of 2C-T-2 in psychotherapy.<ref>Stolaroff, MJ; Wells, C. Preliminary results with new psychoactive agents 2C-T-2 and 2C-T-7. In Jahrbuch für Ethnomedizin und Bewußtseinsforschung (Yearbook of Ethnomedicine and the Study of Consciousness); Rätsch, C; Baker, J, Eds., 1993; Vol. 2, pp 99–117. (MAPS.org) | http://www.maps.org/images/pdf/1993_stolaroff_1.pdf</ref> Based on the experiences of forty participants in the study who took 2C-T-2, Stolaroff compared the effects favorably to [[MDMA]], describing it as more emotionally opening and permitting a wider exploration of feelings and thoughts.

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{{effects/base

|{{effects/physical|

*'''[[Effect::Spontaneous ~~tactile~~ sensations]]''' - The "body high" of 2C-T-2 can be described as very intense and uncomfortable in comparison to [[2C-E]] or [[2C-B]]. In high doses, it's capable of causing painful cramping. It is similar yet distinct from the "body high" experienced on [[2C-T-7]], but is considered much more unpleasant. The sensation itself can be described as intense and may manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.

*'''[[Effect::Stimulation]]''' - 2C-T-2 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other [[phenethylamines]] such as [[2C-B]], [[2C-E]] and [[2C-P]].

*'''[[Effect::Stimulation]]''' - In terms of its effects on the physical energy levels of the user, 2C-T-2 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other [[phenethylamines]] such as [[2C-B]], [[2C-E]] and [[2C-P]].

*'''[[Effect::Spontaneous physical sensations]]''' - The "body high" of 2C-T-2 can be described as very intense and uncomfortable in comparison to [[2C-E]] or [[2C-B]]. In high doses, it's capable of causing painful cramping. It is similar yet distinct from the "body high" experienced on [[2C-T-7]], but is considered much more unpleasant. The sensation itself can be described as intense and may manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.

*'''[[Effect::Bodily control enhancement]]''' - Although this component is capable of manifesting itself in a distinct and noticeable fashion for most users, it does not generally seem to be as apparent or intense as the same component found within [[LSD]] and [[2C-B]].

*'''[[Effect::Tactile enhancement]]'''

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*'''[[Effect::Stomach cramps]]'''

*'''[[Effect::Vasoconstriction]]'''

*'''[[Effect::Diarrhea]]'''

*'''[[Effect::Temperature regulation suppression]]'''

**'''[[Effect::Increased bodily temperature]]'''

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}}

===Experience reports===

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==Toxicity and harm potential==

{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}

The toxicity and long-term health effects of recreational 2C-T-2 use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. Anecdotal ~~evidence from people who have tried 2C-T-2 within the [[psychedelic]] community suggests~~ that there are [[Toxicity::no negative health effects attributed to trying this drug]], but nothing can be completely guaranteed.

The toxicity and long-term health effects of recreational 2C-T-2 use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.

Anecdotal reports suggest that there are [[Toxicity::no negative health effects attributed to trying this drug]], but nothing can be completely guaranteed.

It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance.

~~It is strongly recommended that one use [[responsible drug use|harm reduction practices]], such as [[volumetric dosing]], when using this substance to ensure the administration of the intended dose.~~

===Tolerance and addiction potential===

2C-T-2 is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating.

@@ Line 6: / Line 6: @@
 C-T-2 was first synthesized and tested for activity in humans by [[Alexander Shulgin]] in 1981<ref>Shulgin, Alexander. "Pharmacology Lab Notes #4". Lafayette, CA. (1981-1982). p474 (Erowid.org) | https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebook4_searchable.pdf</ref> and described in his 1991 book [[PiHKAL]] ("Phenethylamines I Have Known and Loved").<ref name="pihkal2CT2">Shulgin, A., & Shulgin, A. (1991).
-  [http://isomerdesign.com/PiHKAL/read.php?id=33 IsomerDesign: "PiHKAL" - #33 - 2C-I]. Retrieved Jan 22, 2018.</ref> It is a member of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important [[phenethylamine]]-derived compounds, all of which except [[mescaline]] he developed and synthesized himself. They are found within the first book of [[PiHKAL]], and are as follows: [[Mescaline]], [[DOM]], [[2C-B]], 2C-E, [[2C-T-2]] and [[2C-T-7]].<ref name="pihkalweb">Shulgin, A., & Shulgin, A. (1991). [https://www.erowid.org/library/books_online/pihkal/pihkal.shtml Erowid Online Books: "PIHKAL" - The Chemical Story]. Retrieved April 14, 2017.</ref>
+  [http://isomerdesign.com/PiHKAL/read.php?id=33 IsomerDesign: "PiHKAL" - #33 - 2C-I]. Retrieved Jan 22, 2018.</ref> It is a member of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important [[phenethylamine]]-derived compounds, all of which except [[mescaline]] he developed and synthesized himself. They are found within the first book of [[PiHKAL]], and are as follows: [[mescaline]], [[DOM]], [[2C-B]], 2C-E, [[2C-T-2]] and [[2C-T-7]].<ref name="pihkalweb">Shulgin, A., & Shulgin, A. (1991). [https://www.erowid.org/library/books_online/pihkal/pihkal.shtml Erowid Online Books: "PIHKAL" - The Chemical Story]. Retrieved April 14, 2017.</ref>
 Following the initial positive results found by Shulgin's research group, a more formal study was carried out by psychedelic psychotherapy pioneer Myron J. Stolaroff who was interested in evaluating the potential use of 2C-T-2 in psychotherapy.<ref>Stolaroff, MJ; Wells, C. Preliminary results with new psychoactive agents 2C-T-2 and 2C-T-7. In Jahrbuch für Ethnomedizin und Bewußtseinsforschung (Yearbook of Ethnomedicine and the Study of Consciousness); Rätsch, C; Baker, J, Eds., 1993; Vol. 2, pp 99–117. (MAPS.org) | http://www.maps.org/images/pdf/1993_stolaroff_1.pdf</ref> Based on the experiences of forty participants in the study who took 2C-T-2, Stolaroff compared the effects favorably to [[MDMA]], describing it as more emotionally opening and permitting a wider exploration of feelings and thoughts.
@@ Line 35: / Line 35: @@
 {{effects/base
 |{{effects/physical|
-*'''[[Effect::Spontaneous tactile sensations]]''' - The "body high" of 2C-T-2 can be described as very intense and uncomfortable in comparison to [[2C-E]] or [[2C-B]]. In high doses, it's capable of causing painful cramping. It is similar yet distinct from the "body high" experienced on [[2C-T-7]], but is considered much more unpleasant. The sensation itself can be described as intense and may manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
+*'''[[Effect::Stimulation]]''' - 2C-T-2 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other [[phenethylamines]] such as [[2C-B]], [[2C-E]] and [[2C-P]].
-*'''[[Effect::Stimulation]]''' - In terms of its effects on the physical energy levels of the user, 2C-T-2 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other [[phenethylamines]] such as [[2C-B]], [[2C-E]] and [[2C-P]].
+*'''[[Effect::Spontaneous physical sensations]]''' - The "body high" of 2C-T-2 can be described as very intense and uncomfortable in comparison to [[2C-E]] or [[2C-B]]. In high doses, it's capable of causing painful cramping. It is similar yet distinct from the "body high" experienced on [[2C-T-7]], but is considered much more unpleasant. The sensation itself can be described as intense and may manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
 *'''[[Effect::Bodily control enhancement]]''' - Although this component is capable of manifesting itself in a distinct and noticeable fashion for most users, it does not generally seem to be as apparent or intense as the same component found within [[LSD]] and [[2C-B]].
 *'''[[Effect::Tactile enhancement]]'''
@@ Line 42: / Line 42: @@
 *'''[[Effect::Stomach cramps]]'''
 *'''[[Effect::Vasoconstriction]]'''
+*'''[[Effect::Diarrhea]]'''
 *'''[[Effect::Temperature regulation suppression]]'''
 **'''[[Effect::Increased bodily temperature]]'''
@@ Line 106: / Line 107: @@
 }}
 }}
 ===Experience reports===
@@ Line 115: / Line 114: @@
 ==Toxicity and harm potential==
 {{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
-The toxicity and long-term health effects of recreational 2C-T-2 use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. Anecdotal evidence from people who have tried 2C-T-2 within the [[psychedelic]] community suggests that there are [[Toxicity::no negative health effects attributed to trying this drug]], but nothing can be completely guaranteed.
+The toxicity and long-term health effects of recreational 2C-T-2 use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.
+Anecdotal reports suggest that there are [[Toxicity::no negative health effects attributed to trying this drug]], but nothing can be completely guaranteed.
+It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance.
-It is strongly recommended that one use [[responsible drug use|harm reduction practices]], such as [[volumetric dosing]], when using this substance to ensure the administration of the intended dose.
 ===Tolerance and addiction potential===
 C-T-2 is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating.