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'''Microdosing''' (also known as '''psychedelic microdosing''') is the practice of using sub-threshold doses of a psychedelic substance in an attempt to produce a therapeutic or [[nootropic]] effect. Microdosing has been claimed by some to have a wide range of benefits including enhancing productivity, treating symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, boosting creativity and problem-solving abilities, as well as increase spiritual awareness. There is currently no clinical evidence to support these claims, however a number of small scale studies have shown positive outcomes. In 2020 a study by the Beckley Foundation found that a 20 microgram dose of LSD significantly reduced pain perception when compared to a placebo, with results comparable to those observed after administration of opioids.<ref>{{Cite web|url=https://www.leafie.co.uk/psychedelics/5-things-you-need-to-know-about-microdosing/|title=5 things you need to know about microdosing|website=leafie|access-date=16 September 2021}}</ref> | |||
'''Microdosing''' (also known as ''' | |||
While it is possible to microdose with any psychedelic substance, | While the practice has its origins with [[LSD]], it is in theory possible to microdose with any [[psychedelic]] substance. There are a growing body of reports of microdosing [[psilocybin mushrooms]], or psychedelic [[research chemicals]], particularly [[LSD]] analogs such as [[ALD-52]], [[1P-LSD]], [[AL-LAD]] and [[ETH-LAD]]. | ||
Microdoses range from about one tenth of an active dose. A microdose of LSD is generally considered to be between 5-15 micrograms. This can be measured accurately using [[volumetric dosing]] techniques. A microdose of psilocybin mushrooms is harder to determine due to the variations in potency between species and batches; it is generally advised to start with no more than .25g. | |||
==Subjective effects== | |||
The panels below list the effects generally occur at a [[Dosage#Microdose|microdose]] dose for psychedelic substances according to reports by PsychonautWiki contributors. | |||
<div class='flex-panel'> | |||
<div class='flex-column'> | |||
<div class="panel radius"> | |||
<h3 class="panel">[[Psychedelic]]s [[File:eye.svg|x20px|right|link=]]</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
<h4 class="media-heading">Visual</h4> | |||
*'''[[Visual enhancements|Enhancements]]''' (''sub-perceptual'') | |||
</li> | |||
<li class="featured list-item"> | |||
<h4 class="media-heading">Other</h4> | |||
*'''[[Analysis enhancement]]''' (''sub-perceptual'') | |||
*'''[[Conceptual thinking]]''' (''sub-perceptual'') | |||
*'''[[Creativity enhancement]]''' (''sub-perceptual'') | |||
*'''[[Emotionality enhancement]]''' (''sub-perceptual'') | |||
*'''[[Novelty enhancement]]''' (''sub-perceptual'')</li> | |||
*'''[[Spirituality enhancement]]''' (''sub-perceptual'') | |||
</ul> | |||
</div> | |||
<div class="panel radius"> | |||
<h3 class="panel">[[Dissociative]]s [[File:Chain-broken.svg|x20px|right|link=]]</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*'''[[Anxiety suppression]]''' (''sub-perceptual'') | |||
*'''[[Cognitive euphoria]]''' (''sub-perceptual'') | |||
*'''[[Depersonalization]]''' (''sub-perceptual'') | |||
*'''[[Derealization]]''' (''sub-perceptual'') | |||
</ul> | |||
</div> | |||
</div> | |||
<div class='flex-column'> | |||
<div class="panel radius"> | |||
<h3 class="panel">[[Stimulant]]s [[File:Arrow-up.svg|x20px|right|link=]]</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*'''[[Focus enhancement]]''' (''sub-perceptual'') | |||
*'''[[Stimulation]]''' (''sub-perceptual'') | |||
*'''[[Thought acceleration]]''' (''sub-perceptual'') | |||
*'''[[Wakefulness]]''' (''sub-perceptual'') | |||
</ul> | |||
</div> | |||
<div class="panel radius"> | |||
<h3 class="panel">[[Cannabis]] [[File:Cannabis_leaf_%281%29.svg|x23px|right|link=]]</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*'''[[Conceptual thinking]]''' (''sub-perceptual'') | |||
*'''[[Sedation]]''' or '''[[stimulation]]''' (''sub-perceptual'') (depending on the strain) | |||
*'''[[Thought connectivity]]''' (''sub-perceptual'') | |||
*'''[[Thought deceleration]]''' (''sub-perceptual'') | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
<div class='flex-column'> | |||
<div class="panel radius"> | |||
<h3 class="panel">[[Benzodiazepine]]s [[File:McCormick Pills.svg|x20px|right|link=]]</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*'''[[Anxiety suppression]]''' (''sub-perceptual'') | |||
</ul> | |||
</div> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">[[Opioid]]s [[File:Syringe-icon.png|x20px|right|link=]]</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*'''[[Pain relief]]''' (''sub-perceptual'') | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
</div> | |||
==See also== | |||
* [[Psychedelics]] | |||
* [[Volumetric liquid dosing]] | |||
==External links== | |||
*[[wikipedia:Microdosing|Microdosing (Wikipedia)]] | |||
*[[wikipedia:Psychedelic microdosing|Psychedelic microdosing (Wikipedia)]] | |||
==Literature== | |||
*Horsley, R.R., Páleníček, T., Kolin, J., & Valeš, K. (2018). Psilocin and ketamine microdosing: effects of subchronic intermittent microdoses in the elevated plus-maze in male Wistar rats. Behavioural Pharmacology. https://doi.org/10.1097/FBP.0000000000000394 | |||
==References== | |||
<references /> | |||
{{references}} | |||
[[Category:Approval]] |