Talk:Α-PiHP: Difference between revisions

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{{headerpanel|{{Approval}}}}

Notice to Administrator: I need someone to help me out with the SubstanceBox, I apologize, I just wanted to start the page on this with the basic information. Completely new to the site, Sorry if I'm messing anything up!

'''alpha-Pyrrolidinohexiophenone''' (also known as '''α-PiHP''', '''a-PHiP''', and '''4-methyl-alpha-pyrrolidinopentanophenone''') is a lesser-known novel [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] and [[chemical class::pyrrolidinophenone]] classes. It is structurally related to [[MDPV]] and [[A-PHP]] and is one of the latest successors to the [[designer drug]] [[Substituted cathinone|cathinone]] analog [[A-PVP]].

[[Subjective effects]] such as [[euphoria]], [[thought acceleration]], [[disinhibition]] and [[ego inflation]]. It generally comes in the form of either a fine powder or crystallized shards that can produce powerful but short-lived euphoric stimulant effects reported to be more compulsive in nature (and strength) to vaporized [[methamphetamine]]. Like its cathinone predecessors, it is has gained notoriety for its tendency to induce [[compulsive redosing]] and addictive behaviors as well the ability to produce [[Delusions|delusional states]] and [[psychosis]] when abused. The compulsivity induced in A-PiHP seems to be stronger compared to similar substances in this class, as reported by online anecdotal reports.

[[Subjective effects]] such as [[euphoria]], [[thought acceleration]], [[disinhibition]] and [[ego inflation]] occur when taking this substance. It generally comes in the form of either a fine powder or crystallized shards that can produce powerful but short-lived euphoric stimulant effects reported to be more compulsive in nature (and strength) to vaporized [[methamphetamine]]. Like its cathinone predecessors, it is has gained notoriety for its tendency to induce [[compulsive redosing]] and addictive behaviors as well the ability to produce [[Delusions|delusional states]] and [[psychosis]] when abused. The compulsivity induced in A-PiHP seems to be stronger compared to similar substances in this class, as reported by online anecdotal reports.

Very little data exists about the pharmacological properties, metabolism, and toxicity of α-PiHP. It has recently become commonly marketed as a legal, grey-market alternative to [[a-PHP]], [[3-MMC]], and [[A-PVP]], and commercially distributed through online [[research chemical]] vendors.

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The toxicity and long-term health effects of recreational α-PiHP use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because α-PiHP has very little history of human usage.

The toxicity and long-term health effects of recreational α-PiHP use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because α-PiHP has very little history of human usage. However, cases of human use have been know to cause extreme addiction and death in users.

α-PiHP has been reported to be the cause of death in one individual. Due to the similarity of structures and the reported dosages, an attempt to compare the concentrations of α-PVP and α-PHP has been made. In the described case, functional death through intoxication of α-PiHP was accepted as the final cause of death. Other detected substances did not contribute to death due to their very likely distant administration. <ref> (PubMed) | https://pubmed.ncbi.nlm.nih.gov/31751796/ </ref>

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 {{headerpanel|{{Approval}}}}
 {{SummarySheet}}
-{{SubstanceBox/Example}}
+{{SubstanceBox/A-PiHP}}
-Notice to Administrator: I need someone to help me out with the SubstanceBox, I apologize, I just wanted to start the page on this with the basic information. Completely new to the site, Sorry if I'm messing anything up!
 '''alpha-Pyrrolidinohexiophenone''' (also known as '''α-PiHP''', '''a-PHiP''', and '''4-methyl-alpha-pyrrolidinopentanophenone''') is a lesser-known novel [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] and [[chemical class::pyrrolidinophenone]] classes. It is structurally related to [[MDPV]] and [[A-PHP]] and is one of the latest successors to the [[designer drug]] [[Substituted cathinone|cathinone]] analog [[A-PVP]].
-[[Subjective effects]] such as [[euphoria]], [[thought acceleration]], [[disinhibition]] and [[ego inflation]]. It generally comes in the form of either a fine powder or crystallized shards that can produce powerful but short-lived euphoric stimulant effects reported to be more compulsive in nature (and strength) to vaporized [[methamphetamine]]. Like its cathinone predecessors, it is has gained notoriety for its tendency to induce [[compulsive redosing]] and addictive behaviors as well the ability to produce [[Delusions|delusional states]] and [[psychosis]] when abused. The compulsivity induced in A-PiHP seems to be stronger compared to similar substances in this class, as reported by online anecdotal reports.
+[[Subjective effects]] such as [[euphoria]], [[thought acceleration]], [[disinhibition]] and [[ego inflation]] occur when taking this substance. It generally comes in the form of either a fine powder or crystallized shards that can produce powerful but short-lived euphoric stimulant effects reported to be more compulsive in nature (and strength) to vaporized [[methamphetamine]]. Like its cathinone predecessors, it is has gained notoriety for its tendency to induce [[compulsive redosing]] and addictive behaviors as well the ability to produce [[Delusions|delusional states]] and [[psychosis]] when abused. The compulsivity induced in A-PiHP seems to be stronger compared to similar substances in this class, as reported by online anecdotal reports.
 Very little data exists about the pharmacological properties, metabolism, and toxicity of α-PiHP. It has recently become commonly marketed as a legal, grey-market alternative to [[a-PHP]], [[3-MMC]], and [[A-PVP]], and commercially distributed through online [[research chemical]] vendors.
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 {{toxicity}}
 {{Further|Research chemicals#Toxicity and harm potential}}
-The toxicity and long-term health effects of recreational α-PiHP use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because α-PiHP has very little history of human usage.
+The toxicity and long-term health effects of recreational α-PiHP use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because α-PiHP has very little history of human usage. However, cases of human use have been know to cause extreme addiction and death in users.
 α-PiHP has been reported to be the cause of death in one individual. Due to the similarity of structures and the reported dosages, an attempt to compare the concentrations of α-PVP and α-PHP has been made. In the described case, functional death through intoxication of α-PiHP was accepted as the final cause of death. Other detected substances did not contribute to death due to their very likely distant administration. <ref> (PubMed) | https://pubmed.ncbi.nlm.nih.gov/31751796/ </ref>