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Acetylcholine: Difference between revisions
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==The cholinergic system== | ==The cholinergic system== | ||
Acetylcholine acts as a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS). Acetylcholine is also one of many neurotransmitters in the autonomic nervous system (ANS) and is the only neurotransmitter used in the motor division of the somatic nervous system (sensory neurons use glutamate and various peptides at their synapses). It functions as both a neurotransmitter and a neuromodulator. The cholinergic areas of the brain have distinct critical functions which some of them are; attention, memory (long- and short term), motivation, and arousal.<ref>Kapalka, | Acetylcholine acts as a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS). Acetylcholine is also one of many neurotransmitters in the autonomic nervous system (ANS) and is the only neurotransmitter used in the motor division of the somatic nervous system (sensory neurons use glutamate and various peptides at their synapses). It functions as both a neurotransmitter and a neuromodulator. The cholinergic areas of the brain have distinct critical functions which some of them are; attention, memory (long- and short term), motivation, and arousal.<ref>{{cite book | vauthors=((Kapalka, G. M.)) | date= 2010 | chapter=Nutritional and Herbal Therapies for Children and Adolescents | title=Substances Involved in Neurotransmission | publisher=Elsevier | pages=71–99 | url=https://linkinghub.elsevier.com/retrieve/pii/B9780123749277000042 | doi=10.1016/B978-0-12-374927-7.00004-2 | isbn=9780123749277}}</ref> | ||
===Drugs targeting the cholinergic system=== | ===Drugs targeting the cholinergic system=== | ||
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====[[Precursors]]==== | ====[[Precursors]]==== | ||
Supplements such as [[choline bitartrate]], [[citicoline]], [[alpha-GPC]], and [[phosphatidylcholine]] provide choline, the direct building block for acetylcholine. Supplementing them may allow ACh to accumulate at higher levels than that which it otherwise would. Choline is an essential dietary nutrient; for food sources and recommended intake levels, see {{Wikipedia|choline}}.<ref>{{cite journal | vauthors=((Zeisel, S. H.)), ((Costa, K.-A. da)) | journal=Nutrition Reviews | title=Choline: an essential nutrient for public health | volume=67 | issue=11 | pages=615–623 | date= November 2009 | url=https://academic.oup.com/nutritionreviews/article-lookup/doi/10.1111/j.1753-4887.2009.00246.x | issn=00296643 | doi=10.1111/j.1753-4887.2009.00246.x}}</ref> | |||
====[[Antagonists]]==== | ====[[Antagonists]]==== | ||
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==References== | ==References== | ||
{{references}} | {{references}} | ||
[[Category: | [[Category:Neurotransmitter]] | ||
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