Talk:Kratom: Difference between revisions

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"Hepatoxic" should be changed to hepatotoxic as the former is not a recognized word.

* fixed. thanks. --[[User:White|White]] ([[User talk:White|talk]]) 09:45, 12 April 2020 (UTC)

== Interaction Warning ==

Kratom inhibits multiple CYP450 enzymes such as CYP2D6, CYP3A4, and CYP1A2. This has the potential to lead to clinically significant interactions with prescription medication. Also, "Literature indicates that kratom is sometimes fatally mixed with carisoprodol, modafinil, propylhexedrine, Datura stramonium, fentanyl, diphenhydramine, caffeine, morphine, and/or O-desmethyltramadol (Krypton)[7, 8, 21, 35]." (Warner et al 2015) is stated in "The pharmacology and toxicology of kratom: from traditional herb to drug of abuse". Many of the substances listed here are not mentioned as potentially dangerous to mix with kratom.

== Strains section incorrect. Common misunderstanding in kratom ==

Hey there, kratom strains are not made like that.

Quote from reddit:

"The veins are generally red when they're small and young, and if anyone says that all kratom veins are red means they are harvesting too early to meet demands. Because the veins will turn green when properly matured. With that said, the color is completely irrelevant other than for judging the maturity of the leaf."

Red is basically fermented leaves and green is air dryed leaves. Gold/yellow (which is missing) is fermented and air dryed.

White is a mixture of red and green with bones(veins), which are stimulating.

Bones are the leaf veins, which are stimulating and usually not included in kratom except for whites.

Strains are not different species. Strains are blends of different types of kratom, and they can vary between vendors.

Source (with pictures and videos that convinced me):

https://www.reddit.com/r/kratom/comments/fcwhen/the_truth_on_strains_and_production_personally/

[[User:Javgat|Javgat]] ([[User talk:Javgat|talk]]) 01:49, 2 September 2020 (UTC)

== "It is unlikely that one could ingest a lethal dosage of kratom powder as the nausea will force one to vomit at around 8 - 9 grams" ==

This can't be correct. I occasionally consume standard-strength kratom powder and found that my minimum effective dose is about 12 grams. I'm nowhere near vomiting... In raw powder form it's certainly hard to get down without capsules, so I'm sure there is a vomit limit, but 8-9 grams is way too low.

== kratom extracts ==

Kratom extracts(especially mitragynine extrats can be seen as a whole new level to kratom and can even be seen as completely different drug. does anyone think there should be a section to mitragynine and 7ohm as a standalone substance or make a page? im aware that there is already a page on kratom(this page), but it talks about kratom leaf. kratom extract is so much different than that on that aspect [[User:Novadoesntexist|Novadoesntexist]] ([[User talk:Novadoesntexist|talk]]) 13:27, 5 March 2024 (UTC)

@@ Line 18: / Line 18: @@
 "Hepatoxic" should be changed to hepatotoxic as the former is not a recognized word.
 * fixed. thanks. --[[User:White|White]] ([[User talk:White|talk]]) 09:45, 12 April 2020 (UTC)
+== Interaction Warning ==
+Kratom inhibits multiple CYP450 enzymes such as CYP2D6, CYP3A4, and CYP1A2. This has the potential to lead to clinically significant interactions with prescription medication. Also, "Literature indicates that kratom is sometimes fatally mixed with carisoprodol, modafinil, propylhexedrine, Datura stramonium, fentanyl, diphenhydramine, caffeine, morphine, and/or O-desmethyltramadol (Krypton)[7, 8, 21, 35]." (Warner et al 2015) is stated in "The pharmacology and toxicology of kratom: from traditional herb to drug of abuse". Many of the substances listed here are not mentioned as potentially dangerous to mix with kratom.
+== Strains section incorrect. Common misunderstanding in kratom ==
+Hey there, kratom strains are not made like that.
+Quote from reddit:
+"The veins are generally red when they're small and young, and if anyone says that all kratom veins are red means they are harvesting too early to meet demands. Because the veins will turn green when properly matured. With that said, the color is completely irrelevant other than for judging the maturity of the leaf."
+Red is basically fermented leaves and green is air dryed leaves. Gold/yellow (which is missing) is fermented and air dryed.
+White is a mixture of red and green with bones(veins), which are stimulating.
+Bones are the leaf veins, which are stimulating and usually not included in kratom except for whites.
+Strains are not different species. Strains are blends of different types of kratom, and they can vary between vendors.
+Source (with pictures and videos that convinced me):
+https://www.reddit.com/r/kratom/comments/fcwhen/the_truth_on_strains_and_production_personally/
+[[User:Javgat|Javgat]] ([[User talk:Javgat|talk]]) 01:49, 2 September 2020 (UTC)
+== "It is unlikely that one could ingest a lethal dosage of kratom powder as the nausea will force one to vomit at around 8 - 9 grams" ==
+This can't be correct. I occasionally consume standard-strength kratom powder and found that my minimum effective dose is about 12 grams. I'm nowhere near vomiting... In raw powder form it's certainly hard to get down without capsules, so I'm sure there is a vomit limit, but 8-9 grams is way too low.
+== kratom extracts ==
+Kratom extracts(especially mitragynine extrats can be seen as a whole new level to kratom and can even be seen as completely different drug. does anyone think there should be a section to mitragynine and 7ohm as a standalone substance or make a page? im aware that there is already a page on kratom(this page), but it talks about kratom leaf. kratom extract is so much different than that on that aspect [[User:Novadoesntexist|Novadoesntexist]] ([[User talk:Novadoesntexist|talk]]) 13:27, 5 March 2024 (UTC)