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Substituted piperazines: Difference between revisions

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[[File:Piperazine.svg|thumb|right|100px||The structure of the piperazine molecule]]
[[File:Piperazine.svg|thumb|right|100px||The structure of the piperazine molecule]]
'''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects. They can be divided into two classes, the benzylpiperazines such as [[BZP]] itself, and its methylenedioxy analogue [[MDBZP]], and the phenylpiperazines [[mCPP]], [[TFMPP]], and [[MeOPP]].  
'''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects. They can be divided into two classes, the benzylpiperazines such as [[BZP]] itself, and its methylenedioxy analogue [[MDBZP]], and the phenylpiperazines [[mCPP]], [[TFMPP]], and [[MeOPP]]. Some deaths have rarely occurred when consuming BZP, it can increase chances of having seizures.


==Chemistry==
==Chemistry==
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Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring.
Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring.


==Examples==
<div class="flex-panel">
*[[BZP]]
    <div class="flex-column">
*[[mCPP]]
<div class="panel radius">
*[[TFMPP]]
<h3 class="panel-header">Recreational Piperazines</h3>
 
<ul class="featured-table">
<li class="featured list-item">
*[[2C-B-BZP]]
*[[3C-PEP]]
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'')
*[[BZP]] (''Benzylpiperazine'')
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'')
*[[DBZP]] (''1,4-Dibenzylpiperazine'')
*[[MBZP]] (''4-Methyl-1-benzylpiperazine'')
*[[MDBZP]] (''Methylenedioxybenzylpiperazine'')
*[[mCPP]] (''3-Chlorophenylpiperazine'')
*[[MDBZP]] (''3,4-Methylenedioxy-1-benzylpiperazine'')
*[[MeOP]] (''Methoxypiperamide'')
*[[MeOPP]] (''para-methoxyphenylpiperazine'')
*[[MT-45]] (''1-cyclohexyl-4-(1,2-diphenylethyl)piperazine'')
*[[mTFMPP]]
*[[oCPP]] (''2-Chlorophenylpiperazine'')
*[[oMPP]] (''2-Methylphenylpiperazine'')
*[[oMeOPP]] (''2-Methoxyphenylpiperazine'')
*[[oTFMPP]]
*[[pCPP]] (''4-Chlorophenylpiperazine'')
*[[pFPP]] (''4-Fluorophenylpiperazine'')
*[[pTFMPP]]
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'')
</li>
</ul>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Benzylpiperazines</h3>
 
<ul class="featured-table">
<li class="featured list-item">
*[[2C-B-BZP]]
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'')
*[[Befuraline]]
*[[Bifeprunox]]
*[[Buclizine]]
*[[BZP]] (''Benzylpiperazine'')
*[[Chlorbenzoxamine]]
*[[DBZP]]
*[[DF-MDBP]] (''Difluoromethylenedioxybenzylpiperazine'')
*[[Fipexide]]
*[[Imatinib]]
*[[MBZP]]
*[[MDBZP]]
*[[Meclozine]]
*[[MeOP]] (''Methoxypiperamide'')
*[[Piberaline]]
*[[Piribedil]]
*[[RN-1747]]
*[[Sunifiram]]
*[[Trimetazidine]]
*[[TFMCPP]] (''3-Trifluoromethyl-4-chlorophenylpiperazine'')
*[[Vesnarinone]]
</li>
</ul>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Phenylpiperazines</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[2C-B-PP]] (''2,5-dimethoxy-4-bromophenylpiperazine'')
*[[3,4-CFP]] (''3-Chloro-4-fluorophenylpiperazine'')
*[[3C-PEP]]
*[[Acaprazine]]
*[[Aripiprazole]] (''Abilify'')
*[[Bifeprunox]]
*[[Brexpiprazole]]
*[[Cariprazine]]
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'')
*[[Elopiprazole]]
*[[Enciprazine]]
*[[Enpiprazole]]
*[[Ensaculin]]
*[[Etoperidone]]
*[[Flesinoxan]]
*[[Lorpiprazole]]
*[[Mepiprazole]]
*[[mCPP]] (''3-Chlorophenylpiperazine'')
*[[mMeOPP]] (''3-Methoxyphenylpiperazine'')
*[[Naluzotan]]
*[[Naphthylpiperazine]]
*[[Nefazodone]]
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'')
*[[Tolpiprazole]]
*[[Trazodone]]
*[[Vilazodone]]
*[[Vortioxetine]]
</li>
</ul>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Pyrimidinylpiperazine</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[Buspirone]]
*[[Dasatinib]]
*[[Eptapirone]]
*[[Gepirone]]
*[[Ipsapirone]]
*[[Piribedil]]
*[[Quipazine]]
*[[Revospirone]]
*[[Tandospirone]]
*[[Tirilazad]]
*[[Umespirone]]
*[[Zalospirone]]
</li>
</ul>
</div>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Pyridinylpiperazine</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[Azaperone]]
*[[Atevirdine]]
*[[Delavirdine]]
*[[Mirtazapine]]
*[[ORG-12962]]
*[[ORG-37684]]
</li>
</ul>
</div>
</div>
</div>
 
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Other</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[AD-1211]]
*[[AP-238]]
*[[Azaprocin]]
*[[Buclizine]]
*[[Bucinnazine]] (''AP-237'')
*[[Cetirizine]] (''Zyrtec'')
*[[Chlorcyclizine]]
*[[Cinnarizine]]
*[[Cyclizine]]
*[[Diphenpipenol]]
*[[Etodroxizine]]
*[[Flunarizine]]
*[[Homochlorcyclizine]]
*[[Hydroxyzine]]
*[[Meclizine]]
*[[MT-45]] (''IC-6'')
*[[NSI-189]]
*[[Oxatomide]]
*[[Perospirone]]
*[[Pipoxizine]]
*[[Tiospirone]]
*[[Unifiram]]
 
</li>
</ul>
</div>
</div>
</div>


==Pharmacology==
==Pharmacology==
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==External links==
==External links==
*[Piperazine (Wikipedia)https://en.wikipedia.org/wiki/Piperazine]
*[https://en.wikipedia.org/wiki/Substituted_piperazine Substituted piperazine (Wikipedia)]
*[https://en.wikipedia.org/wiki/Substituted_piperazine Substituted piperazine (Wikipedia)]
*[https://erowid.org/chemicals/piperazines/piperazines.shtml Piperazines (Erowid Vault)]


==References==
==References==
{{references}}
{{references}}
[[Category:Chemical class]]
[[Category:Piperazine|*]]
Retrieved from "http://psy.st/wiki/Substituted_piperazines"