Template:BenzoOD: Difference between revisions

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Benzodiazepine overdose is a medical emergency that may lead to a coma, permanent brain injury or death if not treated promptly. Symptoms may include severe [[language suppression|slurred speech]], [[confusion]], [[delusions]], [[respiratory depression]], and non-responsiveness. The user might seem like they are sleepwalking. The user is also more susceptible to consume more of the same or another substance due to their impaired judgement, which is typically not seen with other substances during overdose.

Benzodiazepine overdoses may be treated effectively in a hospital environment, with generally favorable outcomes. Care is primarily supportive in nature, although overdoses are sometimes treated with [[flumazenil]], a GABA<sub>A</sub> antagonist<ref>~~Amrein~~, R.~~, Leishman, B~~., ~~Bentzinger~~, C.~~, & Roncari, G~~. ~~(1987~~). Flumazenil in benzodiazepine ~~antagonism. ''Medical Toxicology and Adverse Drug Experience'', 2(6), 411~~-~~429. PMID: 8306565~~</ref> or additional procedures such as [[adrenaline]] injections if other substances are involved.{{citation needed}}

Benzodiazepine overdoses may be treated effectively in a hospital environment, with generally favorable outcomes. Care is primarily supportive in nature, although overdoses are sometimes treated with [[flumazenil]], a GABA<sub>A</sub> antagonist<ref>{{cite journal | vauthors=((Hoffman, E. J.)), ((Warren, E. W.)) | journal=Clinical Pharmacy | title=Flumazenil: a benzodiazepine antagonist | volume=12 | issue=9 | pages=641–656; quiz 699–701 | date= September 1993 | issn=0278-2677}}</ref> or additional procedures such as [[adrenaline]] injections if other substances are involved.{{citation needed}}

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	Benzodiazepine overdose is a medical emergency that may lead to a coma, permanent brain injury or death if not treated promptly. Symptoms may include severe [[language suppression\|slurred speech]], [[confusion]], [[delusions]], [[respiratory depression]], and non-responsiveness. The user might seem like they are sleepwalking. The user is also more susceptible to consume more of the same or another substance due to their impaired judgement, which is typically not seen with other substances during overdose.		Benzodiazepine overdose is a medical emergency that may lead to a coma, permanent brain injury or death if not treated promptly. Symptoms may include severe [[language suppression\|slurred speech]], [[confusion]], [[delusions]], [[respiratory depression]], and non-responsiveness. The user might seem like they are sleepwalking. The user is also more susceptible to consume more of the same or another substance due to their impaired judgement, which is typically not seen with other substances during overdose.

	Benzodiazepine overdoses may be treated effectively in a hospital environment, with generally favorable outcomes. Care is primarily supportive in nature, although overdoses are sometimes treated with [[flumazenil]], a GABA<sub>A</sub> antagonist<ref>~~Amrein~~, R.~~, Leishman, B~~., ~~Bentzinger~~, C.~~, & Roncari, G~~. ~~(1987~~). Flumazenil in benzodiazepine ~~antagonism. ''Medical Toxicology and Adverse Drug Experience'', 2(6), 411~~-~~429. PMID: 8306565~~</ref> or additional procedures such as [[adrenaline]] injections if other substances are involved.{{citation needed}}		Benzodiazepine overdoses may be treated effectively in a hospital environment, with generally favorable outcomes. Care is primarily supportive in nature, although overdoses are sometimes treated with [[flumazenil]], a GABA<sub>A</sub> antagonist<ref>{{cite journal \| vauthors=((Hoffman, E. J.)), ((Warren, E. W.)) \| journal=Clinical Pharmacy \| title=Flumazenil: a benzodiazepine antagonist \| volume=12 \| issue=9 \| pages=641–656; quiz 699–701 \| date= September 1993 \| issn=0278-2677}}</ref> or additional procedures such as [[adrenaline]] injections if other substances are involved.{{citation needed}}