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Talk:Dangerous drug combinations/Archive 1: Difference between revisions

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=Negative effects=
{{Archive for converted wikitext talk page|from=Talk:Dangerous drug combinations|date=2015-07-23}}
 
{{stub}}
*[http://wiki.tripsit.me/images/d/d6/TripSitDrugComboChart.gif Drug Combinations Index (Offsite)]
*http://www.bluelight.org/vb/threads/108959-Antidepressants-and-Recreational-Drugs-(long!)
*http://wiki.bluelight.org/index.php/Anti-Depressants_and_Recreational_Drugs
 
==Negative effects==


==Severe==
==Severe==
*[[Serotonin Syndrome]]
*[[Serotonin Syndrome]]
*[[Cognitive effects: Psychosis|Psychosis]]
*[[Cognitive effects: Psychosis|Psychosis]]
*[[Cognitive effects: Delusions|Delusions]]
*[[Delusions|Delusions]]
*[[Cognitive effects: Thought loops|Thought loops]]
*[[Thought loops|Thought loops]]
*[[Cognitive effects: Anxiety|Panic Attacks]]
*[[Anxiety|Panic Attacks]]
*[[Physical effect: Seizures|Seizures]]
*[[Physical effect: Seizures|Seizures]]
*Loss of Consciousness(Coma)
*Loss of Consciousness(Coma)
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==Minor==
==Minor==
*[[Cognitive effects: Anxiety|Anxiety]]
*[[Anxiety|Anxiety]]
*[[Cognitive effects: Depression|Depression]]
*[[Depression|Depression]]
*[[Cognitive effects: Mood swings|Mood Swings]]
*[[Cognitive effects: Mood swings|Mood Swings]]
*[[Cognitive effects: Paranoia|Paranoia]]
*[[Paranoia|Paranoia]]
*[[Cognitive effects: Confusion|Confusion]]
*[[Cognitive effects: Confusion|Confusion]]
*[[Cognitive effects: Amnesia|Amnesia]]
*[[Amnesia|Amnesia]]
*[[Physical effects: Sedation|Sedation]]
*[[Sedation|Sedation]]
*[[Physical effects: Loss of motor control|Loss of motor control]]
*[[Motor control loss|Motor control loss]]
*[[Physical effects: Dizziness|Dizziness]]
*[[Physical effects: Dizziness|Dizziness]]
*[[Physical effects: Dehydration|Dehydration]]
*[[Dehydration|Dehydration]]
*[[Physical effects: Nausea|Nausea]]
*[[Nausea|Nausea]]
*[[Physical effects: Head aches|Head aches]]
*[[Physical effects: Head aches|Head aches]]
*[[Physical effects: Vasoconstriction|Vasoconstriction]]
*[[Vasoconstriction|Vasoconstriction]]
*[[Physical effects: Abnormal heart beat|Abnormal heart beat]]
*[[Abnormal heartbeat|Abnormal heartbeat]]
*[[Physical effect: Respiratory depression|minor respiratory depression]]
*[[Physical effect: Respiratory depression|minor respiratory depression]]
*[[Physical effects: Loss of temperature regulation|Loss of temperature regulation]]
*[[Temperature regulation suppression|Temperature regulation suppression]]


*[[Cognitive effects: Thought deceleration|Thought deceleration]]
*[[Thought deceleration|Thought deceleration]]
*[[Cognitive effects: Suppression of emotion|Suppression of emotion]]
*[[Emotion suppression|Emotion suppression]]
*[[Cognitive effects: Suppression of information processing|Suppression of information processing]]
*[[Information processing suppression|Information processing suppression]]
*[[Cognitive effects: Suppression of language|Suppression of language]]
*[[Language suppression|Language suppression]]


other to include:
other to include:
<*[[Disconnective effects: Disconnection from consciousness]]>
*[[Consciousness disconnection]]
*[[Disconnective effects: Detachment plateaus]]
*[[Detachment plateaus]]
*[[Cognitive effects: Time distortion|Time distortion]]>
*[[Time distortion|Time distortion]]


=Prescription Drugs=
=Prescription Drugs=
==SSRIs==


If someone on SSRIs wants to take any hallucinogen, they should abstain from their SSRI for at least double the half life of their SSRI. Complications from SSRI interaction can range from decreased effects to fatal serotonin syndrome.
==MAOIs==
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" | Dangerous combinations
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | MAOI Interactions
|-
| style="font-size:10pt" | '''Common [[MAOI]]s''' || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | Phenelzine || style="font-size:9pt" | [[Phenethylamines]] || style="font-size:9pt" | [[DMT]] (smoked)
|-
| style="font-size:9pt" | Tranylcypramine || style="font-size:9pt" | [[Dissociatives]] || style="font-size:9pt" | [[DMT]] (oral)
|-
| style="font-size:9pt" | Selegiline || style="font-size:9pt" | [[Ibogaine]] || style="font-size:9pt" | [[Mushrooms]]
|-
| style="font-size:9pt" |  || style="font-size:9pt" | cathinones || style="font-size:9pt" | [[4-AcO-DMT]]
|-
| style="font-size:10pt" | '''[[RIMA]]s''' || style="font-size:9pt" | 5-htp || style="font-size:9pt" | [[LSD]]
|-
| style="font-size:9pt" | Brofaromine || style="font-size:9pt" | [[Tramadol]]
|-
| style="font-size:9pt" | Minaprine || style="font-size:9pt" | 4-FA / 5-IAI
|-
| style="font-size:9pt" | Pirlindole || style="font-size:9pt" | [[SSRI]]/SNRI
|-
| style="font-size:9pt" | harmaline || style="font-size:9pt" | TCAs
|-
| style="font-size:9pt" |  || style="font-size:9pt" | Serotonin Releasers
|-
|}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
==SSRI/SNRI antidepressants==
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" | Dangerous combinations
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Serotonin Re-uptake Inhibitor Interactions
|-
| style="font-size:10pt" | '''Common [[SSRI]]s''' || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" |  Lexapro  || style="font-size:9pt" | [[2C-T-7]] || style="font-size:9pt" |
|-
| style="font-size:9pt" | Prozac || style="font-size:9pt" | [[aMT]] / [[aET]] || style="font-size:9pt" |
|-
| style="font-size:9pt" | Zoloft || style="font-size:9pt" | [[Ibogaine]] || style="font-size:9pt" |
|-
| style="font-size:9pt" | Luvox || style="font-size:9pt" | [[Dissociatives]] || style="font-size:9pt" |
|-
| style="font-size:10pt" | '''Common SNRIs''' || style="font-size:9pt" | Tramadol || style="font-size:9pt" |
|-
| style="font-size:9pt" | Cymbalta || style="font-size:9pt" | 5-HTP / [[Serotonin Releasers]]
|-
| style="font-size:9pt" | Effexor || style="font-size:9pt" | [[MAOI]] / [[RIMA]]
|-
|}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If taking any medications for anti-convulsant effects use the following drugs should be abstained from
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" |
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Anti-consultant Interactions
|-
| style="font-size:10pt" | Common Anti-consultants || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | Lithium  || style="font-size:9pt" | All tryptamines || style="font-size:9pt" | 
|-
| style="font-size:9pt" | Valproate || style="font-size:9pt" | All phenethylamines || style="font-size:9pt" |
|-
| style="font-size:9pt" | Diazepam  || style="font-size:9pt" | Ibogaine || style="font-size:9pt" |
|-
| style="font-size:9pt" | Xanax    || style="font-size:9pt" |  || style="font-size:9pt" |
|-
|}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Serotonin Releasers should not be mixed with other serotonin releasers because this can lead to [[Serotonin Syndrome]]
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" |
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Serotonin Releaser interactions
|-
| style="font-size:10pt" | Serotonin Releasers || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | 5-HTP  || style="font-size:9pt" | aMT / aET || style="font-size:9pt" | 
|-
| style="font-size:9pt" | MDMA    || style="font-size:9pt" | 2c-t-7 || style="font-size:9pt" |
|-
| style="font-size:9pt" | bk-MDMA || style="font-size:9pt" | Ayahuasca || style="font-size:9pt" |
|-
| style="font-size:9pt" | MDA    || style="font-size:9pt" | MAOIs || style="font-size:9pt" |
|-
| style="font-size:9pt" | bk-MDMA || style="font-size:9pt" | Dissociatives || style="font-size:9pt" |
|-
| style="font-size:9pt" | 5-APB  || style="font-size:9pt" | Ibogaine || style="font-size:9pt" |
|-
| style="font-size:9pt" | Mephedrone || style="font-size:9pt" |  || style="font-size:9pt" |
|-
|}
 
 
 
 
 
 
 
 


==MAOIs==


In many cases, taking an MAOI can lead to more severe negative effects from hallucinogens (although it actually improves the trip for several drugs). An MAOI can be mixed with mushrooms, mescaline, LSD or vaporized DMT safety which will increase the trip. An MAOI is needed to make DMT orally active and this combination is commonly known as ayahuasca. When taking any other hallucinogens, one must abstain from MAOIs for at least double the drug's half life.


*Atypical antidepressants that have any effect on serotonin or dopamine should be treaded just as carefully as SSRIs.


=Recreational drugs=
==Dissociatives==


Alcohol, GHB/GBL, and Benzos should be avoided while on any dissociative as this can lead to nausea, vertigo, and blackouts


DXM, MXE, PCP, and PCP analogs should not be mixed with any serotonin releasing agents or reuptake inhibitors. Mixing it with 2C-T-7, MDMA, aMT, cocaine or amphetamine can lead to [[Serotonin Syndrome]] because of the effect of these drugs on the SERT.


Ketamine does not have any effect on the SERT and can be used safely with MDMA, however caution should still be taken when using stimulants as well.


==Psychedelics==


DOx chemicals that cause strong vasoconstriction should not be mixed with any stimulants.


==Serotonin Releasers==


The main method of action on this group of drugs is releasing serotonin in the brain. As such they should be used in moderation when mixed with each other and should not be mixed with serotonin reuptake inhibitors.


Common serotonin releasers: [[MDMA]], [[MDA]], MDEA, 6-APB, 5-APB, MDAI, Mephedrone, Methylone


Serotonin reuptake inhibiting hallucinogens: aMT, [[DXM]]


=Possible Heart Risk=


These combinations should be avoided if you have a history of heart complications:
{| class="wikitable" align="left"
*Ketamine should not be mixed with cocaine as there is a high chance of having a heart attack.
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" |
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Alcohol Interactions
|-
| style="font-size:10pt" | Common Substances || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | Beer || style="font-size:9pt" | Ibogaine || style="font-size:9pt" | 
|-
| style="font-size:9pt" | Wine || style="font-size:9pt" | Dissociatives || style="font-size:9pt" |
|-
| style="font-size:9pt" | Vodka || style="font-size:9pt" | Benzos || style="font-size:9pt" |
|-
| style="font-size:9pt" | Moonshine || style="font-size:9pt" |  || style="font-size:9pt" |
|-
|}
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