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Talk:Dangerous drug combinations/Archive 1: Difference between revisions

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{{Archive for converted wikitext talk page|from=Talk:Dangerous drug combinations|date=2015-07-23}}
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*[http://wiki.tripsit.me/images/d/d6/TripSitDrugComboChart.gif Drug Combinations Index (Offsite)]
*http://www.bluelight.org/vb/threads/108959-Antidepressants-and-Recreational-Drugs-(long!)
*http://wiki.bluelight.org/index.php/Anti-Depressants_and_Recreational_Drugs
==Negative effects==
==Severe==
*[[Serotonin Syndrome]]
*[[Cognitive effects: Psychosis|Psychosis]]
*[[Delusions|Delusions]]
*[[Thought loops|Thought loops]]
*[[Anxiety|Panic Attacks]]
*[[Physical effect: Seizures|Seizures]]
*Loss of Consciousness(Coma)
*[[Physical effect: Respiratory depression|Major Respiratory depression]]
*Heart Attack/Stroke
*Death
==Minor==
*[[Anxiety|Anxiety]]
*[[Depression|Depression]]
*[[Cognitive effects: Mood swings|Mood Swings]]
*[[Paranoia|Paranoia]]
*[[Cognitive effects: Confusion|Confusion]]
*[[Amnesia|Amnesia]]
*[[Sedation|Sedation]]
*[[Motor control loss|Motor control loss]]
*[[Physical effects: Dizziness|Dizziness]]
*[[Dehydration|Dehydration]]
*[[Nausea|Nausea]]
*[[Physical effects: Head aches|Head aches]]
*[[Vasoconstriction|Vasoconstriction]]
*[[Abnormal heartbeat|Abnormal heartbeat]]
*[[Physical effect: Respiratory depression|minor respiratory depression]]
*[[Temperature regulation suppression|Temperature regulation suppression]]
*[[Thought deceleration|Thought deceleration]]
*[[Emotion suppression|Emotion suppression]]
*[[Information processing suppression|Information processing suppression]]
*[[Language suppression|Language suppression]]
other to include:
*[[Consciousness disconnection]]
*[[Detachment plateaus]]
*[[Time distortion|Time distortion]]
=Prescription Drugs=
=Prescription Drugs=
==SSRIs==


If someone on an SSRIs wants to take any hallucinogen they should abstain from their SSRI for at least double the half life of their SSRI. Complications from SSRI interaction can range from decreased effects to fatal serotonin syndrome.
==MAOIs==
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" | Dangerous combinations
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | MAOI Interactions
|-
| style="font-size:10pt" | '''Common [[MAOI]]s''' || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | Phenelzine || style="font-size:9pt" | [[Phenethylamines]] || style="font-size:9pt" | [[DMT]] (smoked)
|-
| style="font-size:9pt" | Tranylcypramine || style="font-size:9pt" | [[Dissociatives]] || style="font-size:9pt" | [[DMT]] (oral)
|-
| style="font-size:9pt" | Selegiline || style="font-size:9pt" | [[Ibogaine]] || style="font-size:9pt" | [[Mushrooms]]
|-
| style="font-size:9pt" |  || style="font-size:9pt" | cathinones || style="font-size:9pt" | [[4-AcO-DMT]]
|-
| style="font-size:10pt" | '''[[RIMA]]s''' || style="font-size:9pt" | 5-htp || style="font-size:9pt" | [[LSD]]
|-
| style="font-size:9pt" | Brofaromine || style="font-size:9pt" | [[Tramadol]]
|-
| style="font-size:9pt" | Minaprine || style="font-size:9pt" | 4-FA / 5-IAI
|-
| style="font-size:9pt" | Pirlindole || style="font-size:9pt" | [[SSRI]]/SNRI
|-
| style="font-size:9pt" | harmaline || style="font-size:9pt" | TCAs
|-
| style="font-size:9pt" |  || style="font-size:9pt" | Serotonin Releasers
|-
|}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
==SSRI/SNRI antidepressants==
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" | Dangerous combinations
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Serotonin Re-uptake Inhibitor Interactions
|-
| style="font-size:10pt" | '''Common [[SSRI]]s''' || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" |  Lexapro  || style="font-size:9pt" | [[2C-T-7]] || style="font-size:9pt" |
|-
| style="font-size:9pt" | Prozac || style="font-size:9pt" | [[aMT]] / [[aET]] || style="font-size:9pt" |
|-
| style="font-size:9pt" | Zoloft || style="font-size:9pt" | [[Ibogaine]] || style="font-size:9pt" |
|-
| style="font-size:9pt" | Luvox || style="font-size:9pt" | [[Dissociatives]] || style="font-size:9pt" |
|-
| style="font-size:10pt" | '''Common SNRIs''' || style="font-size:9pt" | Tramadol || style="font-size:9pt" |
|-
| style="font-size:9pt" | Cymbalta || style="font-size:9pt" | 5-HTP / [[Serotonin Releasers]]
|-
| style="font-size:9pt" | Effexor || style="font-size:9pt" | [[MAOI]] / [[RIMA]]
|-
|}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If taking any medications for anti-convulsant effects use the following drugs should be abstained from
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" |
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Anti-consultant Interactions
|-
| style="font-size:10pt" | Common Anti-consultants || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | Lithium  || style="font-size:9pt" | All tryptamines || style="font-size:9pt" | 
|-
| style="font-size:9pt" | Valproate || style="font-size:9pt" | All phenethylamines || style="font-size:9pt" |
|-
| style="font-size:9pt" | Diazepam  || style="font-size:9pt" | Ibogaine || style="font-size:9pt" |
|-
| style="font-size:9pt" | Xanax    || style="font-size:9pt" |  || style="font-size:9pt" |
|-
|}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Serotonin Releasers should not be mixed with other serotonin releasers because this can lead to [[Serotonin Syndrome]]
 
{| class="wikitable" align="left"
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" |
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Serotonin Releaser interactions
|-
| style="font-size:10pt" | Serotonin Releasers || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | 5-HTP  || style="font-size:9pt" | aMT / aET || style="font-size:9pt" | 
|-
| style="font-size:9pt" | MDMA    || style="font-size:9pt" | 2c-t-7 || style="font-size:9pt" |
|-
| style="font-size:9pt" | bk-MDMA || style="font-size:9pt" | Ayahuasca || style="font-size:9pt" |
|-
| style="font-size:9pt" | MDA    || style="font-size:9pt" | MAOIs || style="font-size:9pt" |
|-
| style="font-size:9pt" | bk-MDMA || style="font-size:9pt" | Dissociatives || style="font-size:9pt" |
|-
| style="font-size:9pt" | 5-APB  || style="font-size:9pt" | Ibogaine || style="font-size:9pt" |
|-
| style="font-size:9pt" | Mephedrone || style="font-size:9pt" |  || style="font-size:9pt" |
|-
|}
 
 
 
 
 
 
 
 


==MAOIs==


In many cases taking an MAOI can lead more severe negative effects from hallucinogens although it actually improves the trip for several drugs. An MAOI can be mixed with mushrooms, mescaline, LSD or vaporized DMT safety which will increase the trip; an MAOI is needed to make DMT orally active, this combination is commonly known as ayahuasca. When taking any other hallucinogens one must abstain from MAOIs for at least double the drug's half life.


*Atypical antidepressants that have any effect on serotonin or dopamine should be treaded just as carefully as SSRIs.


=Dissociatives=


Alcohol, GHB/GBL, and Benzos should be avoided while on any dissociative, this can lead to nausea, vertigo and blackouts


DXM should not be mixed with any serotonin releasing agents; mixing it with 2C-T-x, MDMA, aMT, cocaine or amphetamine can lead to Serotonin Syndrome.


MXE releases serotonin in smaller quantities than DXM and precaution should be used when mixed with any of the aforementioned drugs.


=Psychedelics=


DOx chemicals cause strong vasoconstriction and should not be mixed with any stimulants.


=Serotonin Releasers=


The main method of action on this group of drugs is releasing serotonin in the brain, as such they should be used in moderation when mixed with each other and should not be mixed with serotonin reuptake inhibitor.


Common serotonin releasers: [[MDMA]], [[MDA]], MDEA, 6-APB, 5-APB, MDAI, Mephedrone, Methylone


serotonin reuptake inhibiting hallucinogens: aMT, [[DXM]]


=Possible Heart Risk=


These combinations should be avoided if you have a history of heart complications:
{| class="wikitable" align="left"
*Ketamine should not be mixed with cocaine, high chance of heart attack.
! colspan="3" style="background:lightblue;width:200px;font-size:10pt" |
|-
| colspan="3" style="background:lightblue;text-align:center;font-size:12pt" | Alcohol Interactions
|-
| style="font-size:10pt" | Common Substances || style="font-size:10pt" | '''Dangerous Interactions''' || style="font-size:10pt" | '''Safe Interactions'''
|-
| style="font-size:9pt" | Beer || style="font-size:9pt" | Ibogaine || style="font-size:9pt" | 
|-
| style="font-size:9pt" | Wine || style="font-size:9pt" | Dissociatives || style="font-size:9pt" |
|-
| style="font-size:9pt" | Vodka || style="font-size:9pt" | Benzos || style="font-size:9pt" |
|-
| style="font-size:9pt" | Moonshine || style="font-size:9pt" |  || style="font-size:9pt" |
|-
|}
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