Methcathinone: Difference between revisions

>Blackhole
expanded harm reduction, removed "personal experience for what is best for me" on dosage and re-dosing, removed missplaced links, added some links, rephrased some things
>David Hedlund
{{Experience reports|erowid_experience_substance_label=Methcathinone}}
 
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[[Category:Psychoactive substance]][[Category:Proofread]][[Category:Approval]]
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{{SummarySheet}}
{{SummarySheet}}
{{SubstanceBox/Methcathinone}}
{{SubstanceBox/Methcathinone}}


'''Methcathinone''' (also known as '''Ephedrone''' originally, '''Methcat''' and '''CAT''') is a synthetic [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] chemical class. It produces standard [[amphetamine|amphetamine-like]] stimulant effects. It is similar to the [[cathinone]] compounds found in the [[khat]] plant of eastern Africa and [[mephedrone]] in its structure and effects.
'''Methcathinone''' (also known as '''Ephedrone''' and '''MCAT''') is a synthetic [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] chemical class. It produces standard [[amphetamine|amphetamine-like]] stimulant effects. It is similar to the [[cathinone]] compounds found in the [[khat]] plant of eastern Africa and [[mephedrone]] in its structure and effects.


Methcathinone was first synthesised in 1928 in the USA and it was used in the Soviet Union as an antidepressant. It is common in central and eastern Europe, often sold as the more well known [[mephedrone]] or synthesized from OTC drugs containing [[ephedrine]] or [[pseudoephedrine]].
==History and culture==
Methcathinone was first synthesized in 1928 in the USA and it was used in the Soviet Union as an antidepressant. It is common in central and eastern Europe, often sold as the more well known [[mephedrone]] or synthesized from OTC drugs containing [[ephedrine]] or [[pseudoephedrine]].


==Chemistry==
==Chemistry==
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*'''[[Effect::Analysis enhancement]]'''
*'''[[Effect::Analysis enhancement]]'''
*'''[[Effect::Anxiety]]'''
*'''[[Effect::Anxiety]]'''
*'''[[Effects::Cognitive euphoria - Methcathinone is extremely stimulating and energetic.]]'''
*'''[[Effects::Cognitive euphoria]]''' - Methcathinone is extremely stimulating and energetic.
*'''[[Effects::Compulsive redosing]]'''
*'''[[Effects::Compulsive redosing]]'''
*'''[[Effect::Empathy, love, and sociability enhancement]]''' - This particular effect, although distinct, is far less prominent than the same effect found within traditional [[entactogens]] such as [[MDMA]] or [[2C-B]].
*'''[[Effect::Empathy, love, and sociability enhancement]]''' - This particular effect, although distinct, is far less prominent than the same effect found within traditional [[entactogens]] such as [[MDMA]] or [[2C-B]].
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==Toxicity and harm potencial==
==Toxicity and harm potencial==
===Neuro toxicity===
===Neuro toxicity===
Illicit methcathinone manufactured using potassium permanganate oxidation of [[ephedrine]] or [[pseudoephedrine]] has been connected with neurotoxicity caused by [https://en.wikipedia.org/wiki/Manganese manganese] poisoning.<ref>https://www.nejm.org/doi/full/10.1056/NEJMoa072488</ref>
Illicit methcathinone manufactured using potassium permanganate oxidation of [[ephedrine]] or [[pseudoephedrine]] has been connected with neurotoxicity caused by [https://en.wikipedia.org/wiki/Manganese manganese] poisoning.<ref>https://www.nejm.org/doi/full/10.1056/NEJMoa072488</ref>
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It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance.
It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance.


===How to Dose Properly===.
==Legal status==
 
Internationally, methcathinone is a Schedule I controlled substance under the United Nations 1971 Convention on Psychotropic Substances.<ref>https://www.incb.org/incb/en/psychotropics/green-list.html</ref>
It is recommended to plan the total amount of Methcathinone you will take beforehand, how many times you are planning to redose and limit the amount you have accessible accordingly, to minimalize the risk of [[compulsive redosing]].
 
Some people may also advice to tapper the comedown of a high dose, with a low dose after approximately an hour.
 
==Synthesis==


Methcathinone is synthesised most easily by reacting Pseudoephedrine with potassium permanganate, although dichromate may also be used as a oxidizer. The reaction is quite unstable and needs to be held at specifically -15 Celsious, so that the oxidation is subtle and not too energetic, turning Pseudoephedrine into Benzaldehyde. The same goes for the amount of potassium permanganate, it has to be a specific ratio of oxidizer to Pseudoephedrine.
*'''Australia''': Methcathinone is a Schedule 9 controlled substance.<ref>{{cite web|url=https://www.legislation.gov.au/Details/F2019L01471|title=POISONS STANDARD DECEMBER 2019|publisher=Office of Parliamentary Counsel|access-date=December 19, 2019}}</ref>
 
[[File:synth.png|800px]]


==See also==
==See also==
*[[Responsible use]]
*[[Responsible use]]
*[[Stimulants]]
*[[Stimulants]]
*[[Substituted cathinone|Cathinones]]
*[[Substituted cathinone|Cathinones]]
*[[Amphetamine]]
*[[Mephedrone]]
*[[Mephedrone]]
*[[3-MMC]] (''3-methylmethcathinone'')
*[[3-MMC]]
*[[Ethcathinone]]
*[[Ethcathinone]]
*[[Pseudoephidrine]]
*[[Pseudoephedrine]]
 


===Experience reports===
===Experience reports===
 
{{Experience reports|erowid_experience_substance_label=Methcathinone}}
Anecdotal reports which describe the effects of this compound within our [[experience index]] include:
{{#ask: [[Category:Methcathinone]][[Category:Experience reports]]|format=ul|Columns=1}}
 
*[https://erowid.org/experiences/subs/exp_Methcathinone.shtml Erowid Experience Vaults: Methcathinone]
 


==External links==
==External links==
*[https://en.wikipedia.org/wiki/Methcathinone Methcathinone (Wikipedia)]
*[https://en.wikipedia.org/wiki/Methcathinone Methcathinone (Wikipedia)]
*[https://erowid.org/chemicals/cathinone/ Cathinone & Methcathinone (Erowid Vault)]
*[https://isomerdesign.com/PiHKAL/explore.php?id=2003 Methcathinone (Isomer Design)]
*[https://isomerdesign.com/PiHKAL/explore.php?id=2003 Methcathinone (Isomer Design)]
*[https://www.reddit.com/r/Methcathinone/ Methcathinone Subreddit]
*[https://go.drugbank.com/drugs/DB15339 Methcathinone (DrugBank)]


==References==
==References==
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[[Category:Cathinone]]
[[Category:Cathinone]]
[[Category:Stimulant]]
[[Category:Stimulant]]
[[Category:Proofread]]
[[Substitutions::H,H,H,H,H,CH<sub>3</sub>,H]]