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| {{SubstanceBox/Example}} | | {{SubstanceBox/Methcathinone}} |
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| <!-- Please ensure that any new substance articles are first published in the 'Talk' namespace. For example, a new article on substance XYZ should have the title "Talk: XYZ" instead of "XYZ". Once the submitted article has been reviewed and determined to meet the guidelines and standards, it will be published by a staff member. -->
| | '''Methcathinone''' (also known as '''Ephedrone''' and '''MCAT''') is a synthetic [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] chemical class. It produces standard [[amphetamine|amphetamine-like]] stimulant effects. It is similar to the [[cathinone]] compounds found in the [[khat]] plant of eastern Africa and [[mephedrone]] in its structure and effects. |
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| For tips on how to properly format a substance article, please refer to this document: [[Content Style Guide - Substance]]
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| ==History and culture== | | ==History and culture== |
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| | Methcathinone was first synthesized in 1928 in the USA and it was used in the Soviet Union as an antidepressant. It is common in central and eastern Europe, often sold as the more well known [[mephedrone]] or synthesized from OTC drugs containing [[ephedrine]] or [[pseudoephedrine]]. |
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| ==Chemistry==
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| {{chemistry}}
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| ==Pharmacology==
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| {{pharmacology}}
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| ==Subjective effects==
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| {{EffectStub}}
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| {{Preamble/SubjectiveEffects}}
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| {{effects/base
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| |{{effects/physical|
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| If applicable, a brief paragraph summary of the substance's physical effects may be included here.
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| You may select physical effects to add below [[Subjective effect index#Physical effects|here]].
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| *'''[[Effect::Physical effect]]'''
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| *'''[[Effect::Physical effect2]]'''
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| *'''[[Effect::Physical effect3]]'''
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| }}
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| {{effects/visual|
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| If applicable, a brief paragraph summary of the substance's visual effects may be included here.
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| You may select visual effects to add below [[Subjective effect index#Visual effects|here]].
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| ====Enhancements====
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| *'''[[Effect::Visual acuity effect1]]'''
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| ====Distortions====
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| *'''[[Effect::Visual distortion effect1]]'''
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| ====[[Effect::Geometry]]====
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| If applicable, a brief paragraph summary describing the visual geometry produced by the substance may be included here.
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| ====Hallucinatory states====
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| If applicable, a brief summary of the substance's visual effects profile may be written here.
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| *'''[[Effect::Hallucinatory states1]]'''
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| }}
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| |{{effects/cognitive|
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| If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.
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| You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
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| *'''[[Effect::Cognitive effect1]]'''
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| *'''[[Effect::Cognitive effect2]]'''
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| *'''[[Effect::Cognitive effect3]]'''
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| }}
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| {{effects/auditory|
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| If applicable, a brief paragraph summary of the substance's auditory effects may be included here.
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| You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].
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| *'''[[Effect::Auditory effect1]]'''
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| *'''[[Effect::Auditory effect2]]'''
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| }}
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| {{effects/multisensory|
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| If applicable, a brief paragraph summary of the substance's multisensory effects may be included here.
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| You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].
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| *'''[[Effect::Multisensory effect1]]'''
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| *'''[[Effect::Multisensory effect2]]'''
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| }}
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| {{effects/transpersonal|
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| If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.
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| You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].
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| *'''[[Effect::Transpersonal effect1]]'''
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| *'''[[Effect::Transpersonal effect2]]'''
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| }}
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| }}
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| ===Experience reports===
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| There are currently {{#ask:[[Category:SUBSTANCE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].
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| {{#ask: [[Category:SUBSTANCE]][[Category:Experience]]|format=ul|Columns=1}}
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| Additional experience reports can be found here:
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| * [https://www.erowid.org/experiences/subs/exp_SUBSTANCE.shtml Erowid Experience Vaults: SUBSTANCE] <!-- Check the link to see if it exists -->
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| ==Toxicity and harm potential==
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| {{toxicity}}
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| It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
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| ===Lethal dosage===
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| ===Tolerance and addiction potential===
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| ===Dangerous interactions===
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| {{DangerousInteractions}}
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| {{DangerousInteractions/Intro}}
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| ==Legal status==
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| {{LegalStub}}
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| ==See also==
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| *[[Responsible use]]
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| ==External links==
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| (List along order below)
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| * [https://en.wikipedia.org/wiki/SUBSTANCE SUBSTANCE (Wikipedia)]
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| * SUBSTANCE (Erowid Vault)
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| * SUBSTANCE ([''PiHKAL'' or ''TiHKAL''] / Isomer Design)
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| ==Literature==
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| * APA formatted reference
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| Please see the [[citation formatting guide]] if you need assistance properly formatting citations.
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| ==References==
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| <references />
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| [[Category:Psychoactive substance]][[Category:Proofread]][[Category:Approval]]
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| {{headerpanel|{{approval}} {{approval}} {{Joey from bluelight.org}}|Bluelight may have a cool suggestion=bluelight.org}}The best defintion to edit on is NOT a single sentence about some nonsense about not dying. Might not die if the best info is back on. (Joey from bluelight.org){{SummarySheet}}
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| {{SubstanceBox/Methcathinone}}
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| '''Methcathinone''' (also known as '''Ephedrone''' originally, '''Methcat''' and '''CAT''') is a synthetic [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] chemical class. It produces standard [[amphetamine|amphetamine-like]] stimulant effects. It is similar to the [[cathinone]] compounds found in the [[khat]] plant of eastern Africa and [[mephedrone]] in its structure and effects.
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| Methcathinone was first synthesised in 1928 in the USA and it was used in the Soviet Union as an antidepressant. It is common in central and eastern Europe, often sold as the more well known [[mephedrone]] or synthesized from OTC drugs containing [[ephedrine]] or [[pseudoephedrine]]. | |
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| ==Chemistry== | | ==Chemistry== |
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| *'''[[Effect::Analysis enhancement]]''' | | *'''[[Effect::Analysis enhancement]]''' |
| *'''[[Effect::Anxiety]]''' | | *'''[[Effect::Anxiety]]''' |
| *'''[[Effects::Cognitive euphoria - Methcathinone is extremely stimulating and energetic.]]''' | | *'''[[Effects::Cognitive euphoria]]''' - Methcathinone is extremely stimulating and energetic. |
| *'''[[Effects::Compulsive redosing]]''' | | *'''[[Effects::Compulsive redosing]]''' |
| *'''[[Effect::Empathy, love, and sociability enhancement]]''' - This particular effect, although distinct, is far less prominent than the same effect found within traditional [[entactogens]] such as [[MDMA]] or [[2C-B]]. | | *'''[[Effect::Empathy, love, and sociability enhancement]]''' - This particular effect, although distinct, is far less prominent than the same effect found within traditional [[entactogens]] such as [[MDMA]] or [[2C-B]]. |
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| ==How to Dose Properly== | | ==Toxicity and harm potencial== |
| Methcathinone, due to its nature, can often cause extreme compulsive redosing. A good strategy is to pre-plan your experience in advance.
| | ===Neuro toxicity=== |
| To minimalize the risk of compulsive redosing and severe negative effects, follow the below points:
| | Illicit methcathinone manufactured using potassium permanganate oxidation of [[ephedrine]] or [[pseudoephedrine]] has been connected with neurotoxicity caused by [https://en.wikipedia.org/wiki/Manganese manganese] poisoning.<ref>https://www.nejm.org/doi/full/10.1056/NEJMoa072488</ref> |
| ▹Pre-plan the total amount of Methcathinone you will take. Limit the amount you have accessible to that amount.
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| ▹Make a rough timeline of the experience. Plan how many re-doses you will do and when you will re-dose.
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| | ===Dependence and abuse potential=== |
| | Methcathinone, due to its highly addictive nature, can often cause extreme [[compulsive redosing]]. |
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| I have discovered a few ways you can use Methcathinone.
| | It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance. |
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| ①Take a strong or heavy dose and redose twice.
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| This is done by taking a first dose of 250-500mg (T:00:00) Afterwards you take the a redose, which is 40-50% the amount of the first dose (T:00:30-005:0) Which is then followed by a final re-dose, which is 40-50% of the first dose (T:01:15-01:45).
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| ②Take multiple common doses.
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| Take 150-200mg, then redose when it wears off with the same dose. Do a maximum of four doses.
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| | ==Legal status== |
| | Internationally, methcathinone is a Schedule I controlled substance under the United Nations 1971 Convention on Psychotropic Substances.<ref>https://www.incb.org/incb/en/psychotropics/green-list.html</ref> |
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| 0When you take a dosage of Methcathinone, per say 350mg, you have to redose 25 mins later as a 40-50% of the first dose. So you don't comedown.
| | *'''Australia''': Methcathinone is a Schedule 9 controlled substance.<ref>{{cite web|url=https://www.legislation.gov.au/Details/F2019L01471|title=POISONS STANDARD DECEMBER 2019|publisher=Office of Parliamentary Counsel|access-date=December 19, 2019}}</ref> |
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| Its really worth to redose once since actually it will be only a 45 min ride and the 4 hours comedown hell. Gradually decreasing the dose instead aka a redose will make it a ton more manageable.
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| You can then redose another 40% or leave it. But '''don't''' redose more than twice.0
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| 0What I recommend for the comedown is that 60mins after you redosed last to take 20% of the first dose.
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| Then to stop. That's the best method to not have a huge comedown.0
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| 0For a mild stimulating experience, take a light dose first, then redose with a medium dose, then as a final, a medium or medium-high dose. Space the doses out more.0
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| ==Synthesis== | |
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| Methcathinone is synthesised most easily by reacting Pseudoephedrine with KMnO4. The reaction is very specific though. A very specific temperature needs to be achieved, below zero, so that the oxidation is subtle and not too energetic, so that it does not destroy the Pseudoephedrine and make it into Benzaldehyde. The same goes for the amount of KMnO4, it has to be a specific ratio of oxidizer to Pseudoephedrine.
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| [[File:synth.png|1740px]]
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| ==See also== | | ==See also== |
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| *[[Responsible use]] | | *[[Responsible use]] |
| *[[Stimulants]] | | *[[Stimulants]] |
| *[[Substituted cathinone|Cathinones]] | | *[[Substituted cathinone|Cathinones]] |
| *[[Amphetamine]]
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| *[[Mephedrone]] | | *[[Mephedrone]] |
| *[[3-MMC]] (''3-methylmethcathinone'') | | *[[3-MMC]] |
| *[[Ethcathinone]] | | *[[Ethcathinone]] |
| | | *[[Pseudoephedrine]] |
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| ===Experience reports=== | | ===Experience reports=== |
| | | {{Experience reports|erowid_experience_substance_label=Methcathinone}} |
| Anecdotal reports which describe the effects of this compound within our [[experience index]] include:
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| {{#ask: [[Category:Methcathinone]][[Category:Experience reports]]|format=ul|Columns=1}} | |
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| *[https://erowid.org/experiences/subs/exp_Methcathinone.shtml Erowid Experience Vaults: Methcathinone]
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| ==External links== | | ==External links== |
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| *[https://en.wikipedia.org/wiki/Methcathinone Methcathinone (Wikipedia)] | | *[https://en.wikipedia.org/wiki/Methcathinone Methcathinone (Wikipedia)] |
| *[https://erowid.org/chemicals/cathinone/ Cathinone & Methcathinone (Erowid Vault)]
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| *[https://isomerdesign.com/PiHKAL/explore.php?id=2003 Methcathinone (Isomer Design)] | | *[https://isomerdesign.com/PiHKAL/explore.php?id=2003 Methcathinone (Isomer Design)] |
| *[https://www.reddit.com/r/Methcathinone/ Methcathinone Subreddit] | | *[https://go.drugbank.com/drugs/DB15339 Methcathinone (DrugBank)] |
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| ==References== | | ==References== |
| <references />https://bluelight.org/xf/members/joey.390415/
| | {{reflist|2}} |
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| https://bluelight.org/xf/threads/what-was-the-first-research-chemical-that-you-tried-and-when.908924/post-15617257
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| [[Category:Psychoactive substance]] | | [[Category:Psychoactive substance]] |
| [[Category:Cathinone]] | | [[Category:Cathinone]] |
| [[Category:Stimulant]] | | [[Category:Stimulant]] |
| | [[Category:Proofread]] |
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| | [[Substitutions::H,H,H,H,H,CH<sub>3</sub>,H]] |
