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Mephedrone: Difference between revisions
>Mymomwouldbesad m i described the side effects that occur during prolonged use |
>David Hedlund {{Experience reports|erowid_experience_substance_label=4-Methylmethcathinone}} |
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[[Subjective effects]] include [[stimulation]], [[anxiety suppression]], [[disinhibition]], [[empathy, affection, and sociability enhancement|enhanced empathy and sociability]], [[muscle relaxation|relaxation]], [[increased libido]], and [[euphoria]]. It is reported to produce a mixture of classic [[stimulant]] and [[entactogen]]ic effects reminiscent of [[cocaine]] and [[MDMA]].<ref name="Schifano2011" /> It comes in the form of tablets or a powder, which users can swallow, snort, inject or insert rectally. It is also sometimes sold as [[MDMA]] ("molly"). | [[Subjective effects]] include [[stimulation]], [[anxiety suppression]], [[disinhibition]], [[empathy, affection, and sociability enhancement|enhanced empathy and sociability]], [[muscle relaxation|relaxation]], [[increased libido]], and [[euphoria]]. It is reported to produce a mixture of classic [[stimulant]] and [[entactogen]]ic effects reminiscent of [[cocaine]] and [[MDMA]].<ref name="Schifano2011" /> It comes in the form of tablets or a powder, which users can swallow, snort, inject or insert rectally. It is also sometimes sold as [[MDMA]] ("molly"). | ||
Limited data exists about the pharmacological properties, metabolism, and toxicity of mephedrone, and it has little history of human use. Preliminary evidence suggests it may possess neurotoxic and cardiotoxic properties.{{citation needed}} It is highly advised to use [[harm reduction practices]] if using this substance | Limited data exists about the pharmacological properties, metabolism, and toxicity of mephedrone, and it has little history of human use. Preliminary evidence suggests it may possess neurotoxic and cardiotoxic properties.{{citation needed}} It is highly advised to use [[harm reduction practices]] if using this substance. | ||
==Chemistry== | ==Chemistry== | ||
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*'''[[Effect::Disinhibition]]''' | *'''[[Effect::Disinhibition]]''' | ||
*'''[[Effect::Empathy, love, and sociability enhancement]]''' - This particular effect, although distinct, is far less prominent than the same effect found within traditional [[entactogens]] such as [[MDMA]] or [[2C-B]] | *'''[[Effect::Empathy, love, and sociability enhancement]]''' - This particular effect, although distinct, is far less prominent than the same effect found within traditional [[entactogens]] such as [[MDMA]] or [[2C-B]] | ||
*'''[[Effect::Time distortion]]''' - Strong feelings of time compression are common within mephedrone and speed up the experience of time quite | *'''[[Effect::Time distortion]]''' - Strong feelings of time compression are common within mephedrone and speed up the experience of time quite noticeably. | ||
*'''[[Effect::Motivation enhancement]]''' | *'''[[Effect::Motivation enhancement]]''' | ||
*'''[[Effect::Anxiety suppression]]''' | *'''[[Effect::Anxiety suppression]]''' | ||
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}} | }} | ||
===Experience reports=== | ===Experience reports=== | ||
{{Experience reports|erowid_experience_substance_label=4-Methylmethcathinone}} | |||
==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
[[File:HarmCausedByDrugsTable.svg|thumb|upright=1.35|Table from the 2010 ISCD study ranking various drugs (legal and illegal) based on statements by drug-harm experts. Mephedrone was found to be the 13th overall most dangerous drug.<ref name="Nutt_2010">{{cite journal | vauthors = Nutt DJ, King LA, Phillips LD | title = Drug harms in the UK: a multicriteria decision analysis | journal = Lancet | volume = 376 | issue = 9752 | pages = 1558–1565 | date = November 2010 | pmid = 21036393 | doi = 10.1016/S0140-6736(10)61462-6 | s2cid = 5667719 | citeseerx = 10.1.1.690.1283 }}</ref>]] | |||
{{Further|Research chemicals#Toxicity and harm potential}} | {{Further|Research chemicals#Toxicity and harm potential}} | ||
Almost nothing is known about the long-term effects of mephedrone due to its short history of its use.<ref name="Clubbers2010" /> Along side of this, the [[Toxicity::exact toxic dosage is unknown]].<ref>{{cite journal | vauthors=((Winstock, A. R.)), ((Mitcheson, L. R.)), ((Deluca, P.)), ((Davey, Z.)), ((Corazza, O.)), ((Schifano, F.)) | journal=Addiction (Abingdon, England) | title=Mephedrone, new kid for the chop? | volume=106 | issue=1 | pages=154–161 | date= January 2011 | issn=1360-0443 | doi=10.1111/j.1360-0443.2010.03130.x}}</ref> | Almost nothing is known about the long-term effects of mephedrone due to its short history of its use.<ref name="Clubbers2010" /> Along side of this, the [[Toxicity::exact toxic dosage is unknown]].<ref>{{cite journal | vauthors=((Winstock, A. R.)), ((Mitcheson, L. R.)), ((Deluca, P.)), ((Davey, Z.)), ((Corazza, O.)), ((Schifano, F.)) | journal=Addiction (Abingdon, England) | title=Mephedrone, new kid for the chop? | volume=106 | issue=1 | pages=154–161 | date= January 2011 | issn=1360-0443 | doi=10.1111/j.1360-0443.2010.03130.x}}</ref> | ||
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*[https://www.erowid.org/chemicals/4_methylmethcathinone/ Mephedrone (Erowid Vault)] | *[https://www.erowid.org/chemicals/4_methylmethcathinone/ Mephedrone (Erowid Vault)] | ||
*[https://isomerdesign.com/PiHKAL/explore.php?id=2018 Mephedrone (Isomer Design)] | *[https://isomerdesign.com/PiHKAL/explore.php?id=2018 Mephedrone (Isomer Design)] | ||
*[https://go.drugbank.com/drugs/DB13108 Mephedrone (DrugBank)] | |||
*[https://drugs-forum.com/wiki/Mephedrone Mephedrone (Drugs-Forum)] | |||
==References== | ==References== | ||