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2-FEA: Difference between revisions
>Discount Pharmacologist |
>David Hedlund {{Experience reports|erowid_experience_substance_label=2-Fluoroethamphetamine}} |
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==Pharmacology== | ==Pharmacology== | ||
2-FEA has not yet been formally studied to the same extent as traditional [[amphetamines]]. Currently, it is assumed that it most likely acts primarily as a triple [[Reuptake inhibitor|reuptake inhibitor]], and that it releases the neurotransmitters: [[serotonin]], [[dopamine]], and [[norepinephrine]]. 2-FEA likely creates it effects by acting as a releasing agent of said neurotransmitters and/or by binding to- and partially blocking the transporter proteins that normally clear substances from the [[Synaptic cleft|synaptic cleft,]] after they have fulfilled their function of conducting a neural impulse.<ref>Tessel | 2-FEA has not yet been formally studied to the same extent as traditional [[amphetamines]]. Currently, it is assumed that it most likely acts primarily as a triple [[Reuptake inhibitor|reuptake inhibitor]], and that it releases the neurotransmitters: [[serotonin]], [[dopamine]], and [[norepinephrine]]. 2-FEA likely creates it effects by acting as a releasing agent of said neurotransmitters and/or by binding to- and partially blocking the transporter proteins that normally clear substances from the [[Synaptic cleft|synaptic cleft,]] after they have fulfilled their function of conducting a neural impulse.<ref>{{cite journal | vauthors=((Tessel, R. E.)), ((Woods, J. H.)) | journal=The Journal of Pharmacology and Experimental Therapeutics | title=Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships | volume=205 | issue=2 | pages=274–281 | date= May 1978 | issn=0022-3565}}</ref> | ||
==Subjective effects== | ==Subjective effects== | ||
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}} | }} | ||
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===Experience reports=== | ===Experience reports=== | ||
{{Experience reports|erowid_experience_substance_label=2-Fluoroethamphetamine}} | |||
==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
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2-FEA is currently a gray area compound within all parts of the world, meaning its regulation lies in a legal gray area and that it is not known to be specifically illegal ("scheduled") within any country. However, people may still be charged for its possession under certain circumstances such as under analogue laws and with the intent to sell or consume. | 2-FEA is currently a gray area compound within all parts of the world, meaning its regulation lies in a legal gray area and that it is not known to be specifically illegal ("scheduled") within any country. However, people may still be charged for its possession under certain circumstances such as under analogue laws and with the intent to sell or consume. | ||
*'''Canada''': 2-FEA would be considered Schedule I as it is an analogue of Amphetamine.<ref>Controlled Drugs and Substances Act | *'''Canada''': 2-FEA would be considered Schedule I as it is an analogue of Amphetamine.<ref>{{Citation | vauthors=((Branch, L. S.)) | year=2022 | title=Consolidated federal laws of Canada, Controlled Drugs and Substances Act | url=https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html}}</ref> | ||
*'''France''': As of december 2024, 2-FEA is not explicitly scheduled. It is thus legal to possess, although in a grey area.<ref>{{Citation | title=Arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants | url=https://www.legifrance.gouv.fr/loda/id/JORFTEXT000000533085/2020-11-20/}}</ref> | |||
*'''Germany''': 2-FEA is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 19, 2019|language=de}}</ref> as of November 26, 2016.<ref>{{cite web|url=https://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl116s2615.pdf#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl116s2615.pdf%27%5D__1576017393518|title=Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe|publisher=Bundesanzeiger Verlag|access-date=December 19, 2019|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 19, 2019|language=de}}</ref> | *'''Germany''': 2-FEA is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 19, 2019|language=de}}</ref> as of November 26, 2016.<ref>{{cite web|url=https://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl116s2615.pdf#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl116s2615.pdf%27%5D__1576017393518|title=Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe|publisher=Bundesanzeiger Verlag|access-date=December 19, 2019|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 19, 2019|language=de}}</ref> | ||
*'''New Zealand''': 2-FEA is an amphetamine analogue, so is a Schedule 3 controlled substance in New Zealand.<ref> | *'''New Zealand''': 2-FEA is an amphetamine analogue, so is a Schedule 3 controlled substance in New Zealand.<ref>{{Citation | title=Misuse of Drugs Act 1975 No 116 (as at 01 July 2022), Public Act – New Zealand Legislation | url=https://www.legislation.govt.nz/act/public/1975/0116/latest/whole.html}}</ref> | ||
*'''The Netherlands:''' 2-FEA is currently legal, but it is part of a substance group that may be banned soon as part of a recently passed law on New Psychoactive Substances (NPS). <ref>{{Citation|title= Wijziging van de Opiumwet in verband met het toevoegen van een derde lijst met als doel het tegengaan van de productie van en de handel in nieuwe psychoactieve stoffen en enkele andere wijzigingen (Dutch) | year=2024|url=https://www.tweedekamer.nl/kamerstukken/wetsvoorstellen/detail?id=2022Z14042&dossier=36159}}</ref> | |||
*'''Switzerland''': 2-FEA can be considered a controlled substance as a defined derivative of a-methylphenethylamine under Verzeichnis E point 130. It is legal when used for scientific or industrial use.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | *'''Switzerland''': 2-FEA can be considered a controlled substance as a defined derivative of a-methylphenethylamine under Verzeichnis E point 130. It is legal when used for scientific or industrial use.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | ||
*'''United Kingdom''': 2-FEA is considered a Class A drug as a result of the amphetamine analogue clause of the Misuse of Drugs Act 1971.<ref>Misuse of Drugs Act 1971 | *'''United Kingdom''': 2-FEA is considered a Class A drug as a result of the amphetamine analogue clause of the Misuse of Drugs Act 1971.<ref>{{Citation | title=Misuse of Drugs Act 1971 | url=https://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I}}</ref> | ||
==See also== | ==See also== | ||
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*[[3-FEA]] | *[[3-FEA]] | ||
==External links== | |||
*[https://isomerdesign.com/PiHKAL/explore.php?id=2299 3-FEA (Isomer Design)] | |||
==References== | ==References== | ||
<references /> | <references /> | ||