Salvinorin A: Difference between revisions

Salvinorin A also acts as a potent agonist at [[dopamine|D₂]] receptors,<ref name="d2">https://onlinelibrary.wiley.com/doi/abs/10.1002/syn.20647</ref> which may be partially responsible for its hallucinogenic effects.

*'''''Salvia Glutinosa''''' (also known as '''Jupiter's Sage''') is a psychoactive plant which is far less potent than Salvia Recognita. Its native habitat is in forested areas located around Central and East Europe and West Asia, where it grows in partial shade in calcareous soils, at elevations of 330 - 5,250 feet (100 - 1,600 metres) adobe sea level. The plant grows up to a 16-24 inches (40 - 60 cm) tall and hairy leafs that span from 5.1 inches (13 cm) inches with petioles of about 3.1 - 3.9 inches ( 8 - 8 centimetres), and occasional white flowers with many whorls of widely spaced flowers.

Although salvia shares states of hallucinatory structures and out-of-body experiences commonly reported with typical dissociatives ([[NMDA receptor antagonist]]s), this is arguably not sufficient so that it falls under the same classification. For example, the hallucinatory structures (although similar) are vastly different in their style and complexity. Alongside of this, the out-of-body experiences commonly reported with dissociatives are presumed to be triggered by the way in which NMDA receptor antagonists block signals to the conscious mind from other parts of the brain. This is accompanied by a distinctive feeling of dissociation, disconnection and detachment which is not present on salvia as it works on an entirely different set of receptors, the function of which in the human brain is almost entirely unknown.{{citation needed}}

The effects of salvia have a subjectively unique style and pharmacology that is not found within any other category of [[hallucinogen]], this has led many within the [[psychonaut]] community assert that it deserves recognition for falling into an entirely new class of its own. Any compound within this subjective and pharmacological class could potentially be referred to as a "salviagenic". This would also include various other similar analogues such as [[Salvinorin B methoxymethyl ether|Salvinorin B]] and many others.<ref>Salvinorin Analogues; Beyond Salvinorin A (DMT Nexus) | https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=4823</ref>

Salvinorin A is currently being researched in relation to its properties as an anti-addiction drug, and several analogs with improved pharmacokinetic profiles have been shown to have anti-addictive effects as well.<ref>http://www.ncbi.nlm.nih.gov/pubmed/24484985</ref>

*'''Austria:''' Salvinorin A is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).{{citation needed}}

*'''Canada:''' Salvia divinorum and its preparations and derivatives (including Salvinorin A) are schedule IV in Canada.<ref>http://laws-lois.justice.gc.ca/eng/acts/c-38.8/page-15.html#h-34</ref>

*'''Germany:''' Salvinorin A is not controlled in Germany, however Salvia Divinorum was added to BtMG Anlage I, making it illegal to grow, import, possess, sell, or transfer it as of March 1, 2008 <ref>https://www.buzer.de/gesetz/8104/index.htm</ref>

*'''United Kingdom:''' Salvia is legal to produce, supply, or import if sold not for human consumption under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref><ref>https://en.wikipedia.org/wiki/Legal_status_of_Salvia_divinorum</ref>