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NEP: Difference between revisions

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{{SummarySheet}}
{{SummarySheet}}
{{SubstanceBox
{{SubstanceBox/NEP}}
 
    <!-- Special Parameters -->
    |displayClasses={{{displayClasses|}}}
    |MaterialTable_MaxWidth=250px
    |MaterialTable_Title={{PAGENAME}}
 
    <!-- Modules -->
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    |ModuleCombination=false
    |ModuleStructure=true
    |ModuleNomenclature=true
    |ModuleClassMembership=true
    |ModuleROA=true
 
    <!-- Source -->
    |PhotoImageFile=
    |PhotoImageWidth=
    |PhotoImageCaption=
 
    <!-- Combination -->
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    |CombinationImage1_File=
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    |CombinationImage2_Caption=
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    |CombinationImage3_Caption=
    |CombinationImage3_File=
    |CombinationImage3_Width=
 
    <!-- Structure -->
    |MolecularStructureCaption=Molecular structure of N-Ethyl-(nor)-pentedrone
    |SkeletalImageFile=File:N-ethyl-nor-pentedrone.svg
    |SkeletalImageWidth=245px
    |3DImageFile=
    |3DImageWidth=
 
    <!-- Nomenclature -->
    |NameCommon=[[common name::N-Ethylpentedrone]], [[common name::NEP]], [[common name::Ethyl-Pentedrone]]
    |NameSubstitution=N-Ethyl-(nor)-pentedrone
    |NameSystematic=2-(Ethylamino)-1-phenyl-1-pentanone
 
    <!-- Class Membership -->
    |EffectClass=[[Stimulant]]
    |ChemicalClass=[[Substituted cathinone|Cathinone]]
 
    <!-- Dosage/Duration -->
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    |OralROA_Collapsed=false
    |OralROA_Caption=
    |OralROA_Bioavailability=
    |OralROA_Threshold=[[Oral threshold dose::10]] [[Oral dose units::mg]]
    |OralROA_Light=[[Oral min light dose::10]] - [[Oral max light dose::25]] mg
    |OralROA_Common=[[Oral min common dose::25]] - [[Oral max common dose::40]] mg
    |OralROA_Strong=[[Oral min strong dose::40]] - [[Oral max strong dose::60]] mg
    |OralROA_Heavy=[[Oral heavy dose::60]] mg +
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    |OralROA_Duration=[[Oral min total time::4]] - [[Oral max total time::6]] [[Oral total time units::hours]]
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    |InsufflatedROA_Threshold=[[Insufflated threshold dose::10]] [[Insufflated dose units::mg]]
    |InsufflatedROA_Light=[[Insufflated min light dose::10]] - [[Insufflated max light dose::20]] mg
    |InsufflatedROA_Common=[[Insufflated min common dose::20]] - [[Insufflated max common dose::40]] mg
    |InsufflatedROA_Strong=[[Insufflated min strong dose::40]] - [[Insufflated max strong dose::60]] mg
    |InsufflatedROA_Heavy=[[Insufflated heavy dose::60]] mg +
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    |InsufflatedROA_Duration=[[Insufflated min total time::1]] - [[Insufflated max total time::3]] [[Insufflated total time units::hours]]
    |InsufflatedROA_Onset=[[Insufflated min onset time::1]] - [[Insufflated max onset time::8]] [[Insufflated onset time units::minutes]]
    |InsufflatedROA_Comeup=[[Insufflated min comeup time::5]] - [[Insufflated max comeup time::15]] [[Insufflated comeup time units::minutes]]
    |InsufflatedROA_Peak=[[Insufflated min peak time::30]] - [[Insufflated max peak time::60]] [[Insufflated peak time units::minutes]]
    |InsufflatedROA_Offset=[[Insufflated min offset time::30]] - [[Insufflated max offset time::90]] [[Insufflated offset time units::minutes]]
    |InsufflatedROA_Aftereffects=[[Insufflated min afterglow time::1]] - [[Insufflated max afterglow time::4]] [[Insufflated afterglow time units::hours]]
 
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    |SmokedROA_Threshold=[[Smoked threshold dose::5]] [[Smoked dose units::mg]]
    |SmokedROA_Light=[[Smoked min light dose::5]] - [[Smoked max light dose::15]] mg
    |SmokedROA_Common=[[Smoked min common dose::15]] - [[Smoked max common dose::30]] mg
    |SmokedROA_Strong=[[Smoked min strong dose::30]] - [[Smoked max strong dose::50]] mg
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    |SmokedROA_Onset=
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    |SmokedROA_Offset=
    |SmokedROA_Aftereffects=
 
}}
 


'''N-Ethyl-nor-pentedrone''' (also known as '''N-Ethylpentedrone''', '''Ethyl-pentedrone''' or more commonly, '''NEP''') is a lesser-known novel [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] class that produces [[stimulating]], [[euphoric]], and mildly [[entactogenic]] effects when [[Routes of administration|administered]].  
'''N-Ethyl-nor-pentedrone''' (also known as '''N-Ethylpentedrone''', '''Ethyl-pentedrone''' or more commonly, '''NEP''') is a lesser-known novel [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] class that produces [[stimulating]], [[euphoric]], and mildly [[entactogenic]] effects when [[Routes of administration|administered]].  
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==Subjective effects==
==Subjective effects==
{{Preamble/SubjectiveEffects}}                                                                             
{{Preamble/SubjectiveEffects}}                                                                             
{{effects/base
{{effects/base


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*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Time distortion]]'''
*'''[[Effect::Time distortion]]'''
*'''[[Effect::Thought acceleration]]'''
*'''[[Effect::Motivation enhancement]]'''
*'''[[Effect::Motivation enhancement]]'''
*'''[[Effect::Compulsive redosing]]'''
*'''[[Effect::Compulsive redosing]]'''
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*'''Brazil''': On September 7, 2018, all cathinone analogues are controlled substances considered illegal to possess, use and distribute. This was made possible due to a blanket ban law appended to Portaria SVS/MS nº 344.<ref>New blanket ban on synthetic illegal drugs is approved (Portuguese) | http://portal.anvisa.gov.br/noticias/-/asset_publisher/FXrpx9qY7FbU/content/combate-a-drogas-ilicitas-sinteticas-fica-mais-facil</ref>
*'''Brazil''': On September 7, 2018, all cathinone analogues are controlled substances considered illegal to possess, use and distribute. This was made possible due to a blanket ban law appended to Portaria SVS/MS nº 344.<ref>New blanket ban on synthetic illegal drugs is approved (Portuguese) | http://portal.anvisa.gov.br/noticias/-/asset_publisher/FXrpx9qY7FbU/content/combate-a-drogas-ilicitas-sinteticas-fica-mais-facil</ref>
*'''China''': NEP is a controlled substance.{{citation needed}}
*'''China''': NEP is a controlled substance.{{citation needed}}
*'''France''': As a derivative of cathinone with alkyl substitutions on the nitrogen and R2 position, NEP is scheduled as a "stupéfiant", i.e. a recognized drug of abuse. It is illegal to possess, buy, sell or manufacture.<ref>{{Citation | title=Arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants  | url=https://www.legifrance.gouv.fr/loda/id/JORFTEXT000000533085/2020-11-20/}}</ref>
*'''Germany''': NEP is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref> as of November 26, 2016.<ref>{{cite web|url=https://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl116s2615.pdf#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl116s2615.pdf%27%5D__1576017393518|title=Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe|publisher=Bundesanzeiger Verlag|access-date=December 11, 2019|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref>
*'''Germany''': NEP is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref> as of November 26, 2016.<ref>{{cite web|url=https://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl116s2615.pdf#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl116s2615.pdf%27%5D__1576017393518|title=Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe|publisher=Bundesanzeiger Verlag|access-date=December 11, 2019|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref>
*'''Japan''': NEP is a controlled substance.<ref>{{cite web|url=https://www.mhlw.go.jp/seisakunitsuite/bunya/kenkou_iryou/iyakuhin/yakubuturanyou/dl/meisho.pdf|title=指定薬物一覧|publisher=Ministry of Health, Labour and Welfare|access-date=December 27, 2019|language=ja}}</ref>
*'''Japan''': NEP is a controlled substance.<ref>{{cite web|url=https://www.mhlw.go.jp/seisakunitsuite/bunya/kenkou_iryou/iyakuhin/yakubuturanyou/dl/meisho.pdf|title=指定薬物一覧|publisher=Ministry of Health, Labour and Welfare|access-date=December 27, 2019|language=ja}}</ref>
*'''Sweden''': NEP is a controlled substance as of November 12, 2019.<ref>{{cite web|url=https://svenskforfattningssamling.se/sites/default/files/sfs/2019-10/SFS2019-612.pdf|title=Svensk författningssamling: Förordningom ändring i förordningen (1999:58) om förbud mot vissa hälsofarliga varor|language=sv|access-date=December 27, 2019|publisher=Thomson Förlag}}</ref>
*'''Sweden''': NEP is a controlled substance as of November 12, 2019.<ref>{{cite web|url=https://svenskforfattningssamling.se/sites/default/files/sfs/2019-10/SFS2019-612.pdf|title=Svensk författningssamling: Förordningom ändring i förordningen (1999:58) om förbud mot vissa hälsofarliga varor|language=sv|access-date=December 27, 2019|publisher=Thomson Förlag}}</ref>
*'''Switzerland''': NEP can be considered a controlled substance as a defined derivative of Cathinone under Verzeichnis E point 1. It is legal when used for scientific or industrial use.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>
*'''Switzerland''': NEP can be considered a controlled substance as a defined derivative of Cathinone under Verzeichnis E point 1. It is legal when used for scientific or industrial use.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>
*'''The Netherlands:''' NEP is currently legal, but it is part of a substance group that may be banned soon as part of a recently passed law on New Psychoactive Substances (NPS). <ref>{{Citation|title= Wijziging van de Opiumwet in verband met het toevoegen van een derde lijst met als doel het tegengaan van de productie van en de handel in nieuwe psychoactieve stoffen en enkele andere wijzigingen (Dutch) | year=2024|url=https://www.tweedekamer.nl/kamerstukken/wetsvoorstellen/detail?id=2022Z14042&dossier=36159}}</ref>
*'''The Netherlands:''' NEP is a controlled substance as of July 1, 2025. <ref>{{Citation|title= Bepaalde groepen designerdrugs (ook wel nieuwe psychoactieve stoffen) zijn sinds 1 juli 2025 verboden. Deze stoffen zijn schadelijk. Gebruikers kunnen er gezondheidsproblemen van krijgen en er zelfs door overlijden. | year=2025|url=https://www.rijksoverheid.nl/onderwerpen/drugs/verbod-op-designerdrugs}}</ref>
*'''United Kingdom''': NEP is a Class B drug in the United Kingdom as a result of the cathinone catch-all clause.<ref>{{Citation | title=The Misuse of Drugs Act 1971 (Amendment) Order 2010 | url=https://www.legislation.gov.uk/uksi/2010/1207/made}}</ref>
*'''United Kingdom''': NEP is a Class B drug in the United Kingdom as a result of the cathinone catch-all clause.<ref>{{Citation | title=The Misuse of Drugs Act 1971 (Amendment) Order 2010 | url=https://www.legislation.gov.uk/uksi/2010/1207/made}}</ref>
*'''United States''': NEP is not a controlled substance in the United States but possession or distribution for human use could potentially be prosecuted under the Federal Analogue Act due to its structural and pharmacological similarities to [[pentedrone]].<ref>{{Citation | title=21 U.S. Code § 813 - Treatment of controlled substance analogues | url=https://www.law.cornell.edu/uscode/text/21/813}}</ref>
*'''United States''': NEP is not a controlled substance in the United States but possession or distribution for human use could potentially be prosecuted under the Federal Analogue Act due to its structural and pharmacological similarities to [[pentedrone]].<ref>{{Citation | title=21 U.S. Code § 813 - Treatment of controlled substance analogues | url=https://www.law.cornell.edu/uscode/text/21/813}}</ref>
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