NEP: Difference between revisions

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As with its parent compound [[pentedrone]], very little data exists about the pharmacological properties, metabolism, and toxicity of NEP in humans. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be treated with extreme caution. It is highly advised that one use [[responsible drug use|harm reduction practices]] if choosing to use this substance.

~~== Potency of NEP crystals versus NEP Powder ==~~

Anecdotal evidence shows most recent bathes have a drastic difference in potency, especially the NEP Powder, which seems to have 50% potency over the crystals. Keep this in mind that 10mg insufflated when using Crystals has a drastically different effect from 10mg insufflated NEP Powder. It's recommended to limit yourself to 10mg insufflated per dose when using Crystal form. The powder form is generally considered the "mild" NEP. Some people prefer the "mild" version of the NEP crystals, since it will cause less heart strain and other side negative effects. It looks like the crystals don't seem to be simply crushed to powder. Rather an inactive or less active substance seems to added.which decreases potency by a lot. Even when you have a high tolerance you will notice the difference between the Crystals and Powder when insufflated. The smell of the crystals is also way more prominent and becomes an unpleasant odor. While the powder barely changes in smell, even after a year.

==Chemistry==

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==Subjective effects==

{{effects/base

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*'''[[Effect::Tactile enhancement]]'''

*'''[[Effect::Dehydration]]''' - Dry mouth and increased sweating can occur after consuming NEP. Low doses of the substance in question cause minimal dehydration.

*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting~~. although some reports mention moderate to extreme vasoconstriction~~.

*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting.

*'''[[Effect::Abnormal heartbeat]]'''

*'''[[Effect::Increased blood pressure]]'''

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*'''[[Effect::Increased music appreciation]]'''

*'''[[Effect::Time distortion]]'''

*'''[[Effect::Thought acceleration]]'''

*'''[[Effect::Motivation enhancement]]'''

*'''[[Effect::Compulsive redosing]]'''

*'''[[Effect::Increased libido]]'''

}}

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*'''Brazil''': On September 7, 2018, all cathinone analogues are controlled substances considered illegal to possess, use and distribute. This was made possible due to a blanket ban law appended to Portaria SVS/MS nº 344.<ref>New blanket ban on synthetic illegal drugs is approved (Portuguese) | http://portal.anvisa.gov.br/noticias/-/asset_publisher/FXrpx9qY7FbU/content/combate-a-drogas-ilicitas-sinteticas-fica-mais-facil</ref>

*'''China''': NEP is a controlled substance.{{citation needed}}

*'''France''': As a derivative of cathinone with alkyl substitutions on the nitrogen and R2 position, NEP is scheduled as a "stupéfiant", i.e. a recognized drug of abuse. It is illegal to possess, buy, sell or manufacture.<ref>{{Citation | title=Arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants | url=https://www.legifrance.gouv.fr/loda/id/JORFTEXT000000533085/2020-11-20/}}</ref>

*'''Germany''': NEP is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref> as of November 26, 2016.<ref>{{cite web|url=https://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl116s2615.pdf#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl116s2615.pdf%27%5D__1576017393518|title=Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe|publisher=Bundesanzeiger Verlag|access-date=December 11, 2019|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref>

*'''Japan''': NEP is a controlled substance.<ref>{{cite web|url=https://www.mhlw.go.jp/seisakunitsuite/bunya/kenkou_iryou/iyakuhin/yakubuturanyou/dl/meisho.pdf|title=指定薬物一覧|publisher=Ministry of Health, Labour and Welfare|access-date=December 27, 2019|language=ja}}</ref>

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 As with its parent compound [[pentedrone]], very little data exists about the pharmacological properties, metabolism, and toxicity of NEP in humans. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be treated with extreme caution. It is highly advised that one use [[responsible drug use|harm reduction practices]] if choosing to use this substance.
-== Potency of NEP crystals versus NEP Powder ==
-Anecdotal evidence shows most recent bathes have a drastic difference in potency, especially the NEP Powder, which seems to have 50% potency over the crystals. Keep this in mind that 10mg insufflated when using Crystals has a drastically different effect from 10mg insufflated NEP Powder. It's recommended to limit yourself to 10mg insufflated per dose when using Crystal form. The powder form is generally considered the "mild" NEP. Some people prefer the "mild" version of the NEP crystals, since it will cause less heart strain and other side negative effects. It looks like the crystals don't seem to be simply crushed to powder. Rather an inactive or less active substance seems to added.which decreases potency by a lot. Even when you have a high tolerance you will notice the difference between the Crystals and Powder when insufflated. The smell of the crystals is also way more prominent and becomes an unpleasant odor. While the powder barely changes in smell, even after a year.
 ==Chemistry==
@@ Line 23: / Line 20: @@
 ==Subjective effects==
 {{Preamble/SubjectiveEffects}}
 {{effects/base
@@ Line 31: / Line 29: @@
 *'''[[Effect::Tactile enhancement]]'''
 *'''[[Effect::Dehydration]]''' - Dry mouth and increased sweating can occur after consuming NEP. Low doses of the substance in question cause minimal dehydration.
-*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting. although some reports mention moderate to extreme vasoconstriction.
+*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting.
 *'''[[Effect::Abnormal heartbeat]]'''
 *'''[[Effect::Increased blood pressure]]'''
@@ Line 54: / Line 52: @@
 *'''[[Effect::Increased music appreciation]]'''
 *'''[[Effect::Time distortion]]'''
-*'''[[Effect::Thought acceleration]]'''
 *'''[[Effect::Motivation enhancement]]'''
 *'''[[Effect::Compulsive redosing]]'''
-*'''[[Effect::Increased libido]]'''
 }}
@@ Line 114: / Line 110: @@
 *'''Brazil''': On September 7, 2018, all cathinone analogues are controlled substances considered illegal to possess, use and distribute. This was made possible due to a blanket ban law appended to Portaria SVS/MS nº 344.<ref>New blanket ban on synthetic illegal drugs is approved (Portuguese) | http://portal.anvisa.gov.br/noticias/-/asset_publisher/FXrpx9qY7FbU/content/combate-a-drogas-ilicitas-sinteticas-fica-mais-facil</ref>
 *'''China''': NEP is a controlled substance.{{citation needed}}
+*'''France''': As a derivative of cathinone with alkyl substitutions on the nitrogen and R2 position, NEP is scheduled as a "stupéfiant", i.e. a recognized drug of abuse. It is illegal to possess, buy, sell or manufacture.<ref>{{Citation | title=Arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants  | url=https://www.legifrance.gouv.fr/loda/id/JORFTEXT000000533085/2020-11-20/}}</ref>
 *'''Germany''': NEP is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref> as of November 26, 2016.<ref>{{cite web|url=https://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl116s2615.pdf#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl116s2615.pdf%27%5D__1576017393518|title=Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe|publisher=Bundesanzeiger Verlag|access-date=December 11, 2019|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 11, 2019|language=de}}</ref>
 *'''Japan''': NEP is a controlled substance.<ref>{{cite web|url=https://www.mhlw.go.jp/seisakunitsuite/bunya/kenkou_iryou/iyakuhin/yakubuturanyou/dl/meisho.pdf|title=指定薬物一覧|publisher=Ministry of Health, Labour and Welfare|access-date=December 27, 2019|language=ja}}</ref>