DOM: Difference between revisions

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*'''[[Tramadol]]''' - Tramadol lowers the seizure threshold<ref>{{cite journal | vauthors=((Talaie, H.)), ((Panahandeh, R.)), ((Fayaznouri, M. R.)), ((Asadi, Z.)), ((Abdollahi, M.)) | journal=Journal of Medical Toxicology | title=Dose-independent occurrence of seizure with tramadol | volume=5 | issue=2 | pages=63–67 | date= June 2009 | url=http://link.springer.com/10.1007/BF03161089 | issn=1556-9039 | doi=10.1007/BF03161089}}</ref> and [[psychedelics]] may act as triggers for seizures, particularly in those who are predisposed to them.{{citation needed}}

*'''[[DangerousInteraction::Lithium]]''':<ref>{{Citation | vauthors=((Nayak, S.)), ((Gukasyan, N.)), ((Barrett, F. S.)), ((Erowid, E.)), ((Erowid, F.)), ((Griffiths, R. R.)) | year=2021 | title=Classic psychedelic coadministration with lithium, but not lamotrigine, is associated with seizures: an analysis of online psychedelic experience reports | publisher=PsyArXiv | url=https://osf.io/r726d}}</ref> Lithium is commonly prescribed in the treatment of bipolar disorder; however, there is a large body of anecdotal evidence that suggests taking it with psychedelics can significantly increase the risk of [[psychosis]] and [[seizures]].<ref>{{cite web|url=https://erowid.org/experiences/exp.php?ID=83935|title=A Nice Little Trip to the Hospital: Lithium & LSD|author=<nowiki>"wanderlei"</nowiki>|publisher=Erowid|publication-date=October 3, 2010|access-date=January 7, 2020|id=ExpID: 83935|work=Erowid Experience Vaults}}</ref><ref>{{cite web|url=https://erowid.org/experiences/exp.php?ID=75153|title=Having a Seizure and Passing Out: Lithium & LSD|author=<nowiki>"MissDja1a"</nowiki>|publisher=Erowid|publication-date=December 16, 2008|access-date=January 7, 2020|id=ExpID: 75153|work=Erowid Experience Vaults}}</ref><ref>{{cite web|url=https://www.reddit.com/r/Psychonaut/comments/17uspp/please_read_a_cautionary_tale_concerning_lsd|title=Please Read: a cautionary tale concerning LSD|author=<nowiki>"throwaway_naut"</nowiki>|publisher=Reddit|work=r/Psychonaut|year=2014|access-date=January 7, 2020}}</ref> As a result, this combination should be '''strictly avoided'''.

*'''[[Stimulants]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis~~.{{citation needed}}~~

*'''[[[[UnsafeInteraction::Tramadol|Tramadol]]]]''' - Tramadol lowers the seizure threshold<ref>{{cite journal | vauthors=((Talaie, H.)), ((Panahandeh, R.)), ((Fayaznouri, M. R.)), ((Asadi, Z.)), ((Abdollahi, M.)) | journal=Journal of Medical Toxicology | title=Dose-independent occurrence of seizure with tramadol | volume=5 | issue=2 | pages=63–67 | date= June 2009 | url=http://link.springer.com/10.1007/BF03161089 | issn=1556-9039 | doi=10.1007/BF03161089}}</ref> and [[psychedelics]] may act as triggers for seizures, particularly in those who are predisposed to them.{{citation needed}}

*'''[https://en.wikipedia.org/wiki/Lithium_(medication) Lithium]''' - Lithium is often used as treatment for bipolar disorder. It may possibly cause elevated risk of seizures and psychosis due to its [[Glutamate|glutaminergic]] and [[GABA|GABAergic]] effects.{{citation needed}}

*'''[[[[UncertainInteraction::Stimulants|Stimulants]]]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis.{{citation needed}}

==Legal status==

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 {{DangerousInteractions/Intro}}
-*'''[[Tramadol]]''' - Tramadol lowers the seizure threshold<ref>{{cite journal | vauthors=((Talaie, H.)), ((Panahandeh, R.)), ((Fayaznouri, M. R.)), ((Asadi, Z.)), ((Abdollahi, M.)) | journal=Journal of Medical Toxicology | title=Dose-independent occurrence of seizure with tramadol | volume=5 | issue=2 | pages=63–67 | date= June 2009 | url=http://link.springer.com/10.1007/BF03161089 | issn=1556-9039 | doi=10.1007/BF03161089}}</ref> and [[psychedelics]] may act as triggers for seizures, particularly in those who are predisposed to them.{{citation needed}}
+*'''[[DangerousInteraction::Lithium]]''':<ref>{{Citation | vauthors=((Nayak, S.)), ((Gukasyan, N.)), ((Barrett, F. S.)), ((Erowid, E.)), ((Erowid, F.)), ((Griffiths, R. R.)) | year=2021 | title=Classic psychedelic coadministration with lithium, but not lamotrigine, is associated with seizures: an analysis of online psychedelic experience reports | publisher=PsyArXiv | url=https://osf.io/r726d}}</ref> Lithium is commonly prescribed in the treatment of bipolar disorder; however, there is a large body of anecdotal evidence that suggests taking it with psychedelics can significantly increase the risk of [[psychosis]] and [[seizures]].<ref>{{cite web|url=https://erowid.org/experiences/exp.php?ID=83935|title=A Nice Little Trip to the Hospital: Lithium & LSD|author=<nowiki>&quot;wanderlei&quot;</nowiki>|publisher=Erowid|publication-date=October 3, 2010|access-date=January 7, 2020|id=ExpID: 83935|work=Erowid Experience Vaults}}</ref><ref>{{cite web|url=https://erowid.org/experiences/exp.php?ID=75153|title=Having a Seizure and Passing Out: Lithium & LSD|author=<nowiki>&quot;MissDja1a&quot;</nowiki>|publisher=Erowid|publication-date=December 16, 2008|access-date=January 7, 2020|id=ExpID: 75153|work=Erowid Experience Vaults}}</ref><ref>{{cite web|url=https://www.reddit.com/r/Psychonaut/comments/17uspp/please_read_a_cautionary_tale_concerning_lsd|title=Please Read: a cautionary tale concerning LSD|author=<nowiki>&quot;throwaway_naut&quot;</nowiki>|publisher=Reddit|work=r/Psychonaut|year=2014|access-date=January 7, 2020}}</ref> As a result, this combination should be '''strictly avoided'''.
-*'''[[Stimulants]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis.{{citation needed}}
+*'''[[[[UnsafeInteraction::Tramadol|Tramadol]]]]''' - Tramadol lowers the seizure threshold<ref>{{cite journal | vauthors=((Talaie, H.)), ((Panahandeh, R.)), ((Fayaznouri, M. R.)), ((Asadi, Z.)), ((Abdollahi, M.)) | journal=Journal of Medical Toxicology | title=Dose-independent occurrence of seizure with tramadol | volume=5 | issue=2 | pages=63–67 | date= June 2009 | url=http://link.springer.com/10.1007/BF03161089 | issn=1556-9039 | doi=10.1007/BF03161089}}</ref> and [[psychedelics]] may act as triggers for seizures, particularly in those who are predisposed to them.{{citation needed}}
-*'''[https://en.wikipedia.org/wiki/Lithium_(medication) Lithium]''' - Lithium is often used as treatment for bipolar disorder. It may possibly cause elevated risk of seizures and psychosis due to its [[Glutamate|glutaminergic]] and [[GABA|GABAergic]] effects.{{citation needed}}
+*'''[[[[UncertainInteraction::Stimulants|Stimulants]]]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis.{{citation needed}}
 ==Legal status==