Talk:Fluetizolam: Difference between revisions

← Older edit

@@ Line 1: / Line 1: @@
+{{headerpanel|{{DepressantOD|thienodiazepines}}}}
-==Chemistry==
+'''Fluetizolam''' (also known as '''2'-Fluorodeschloroetizolam''' or '''FluEtiz''') is a designer drug in the thienodiazepine family of drugs. It’s closely related to drugs like diazepam (Valium), alprazolam (Xanax), and clonazolam (Klonopin). It was patented in Japan by Yoshitomi Pharmaceutical in the 90s but never made it to market. It’s been “rediscovered” as a designer drug and is revered for being a particularly potent alternative to etizolam. The threshold dose for this substance is well below 1 mg. It’s used for managing anxiety, insomnia, and side effects of other drugs. Some users take it for its inebriating effects, which resemble the effects of alcohol or GHB.
-Fluetizolam could also be name (2'-)Fluorodeschloroetizolam, although the ''des-'' notation is deprecated in modern naming standards.{{citation needed}}
+=== Metabolism ===
+Fluetizolam is extensively metabolized into an active metabolite α-hydroxyetizolam by the process of hydroxylation. The active metabolite also has an action similar to that of fluetizolam. CYP3A4 is the major cytochrome enzyme responsible for metabolism. The inactive metabolites are removed from the body through urine and feces, with the drug’s half-life ranging from 3 to 17 hours
+=== Potency ===
+Preliminary studies on this compound suggest it to be 6 to 10 times more potent than diazepam. And about 2 to 3 time as potent as Etizolam. This makes Fluetizolam a very potent benzo with a common dosage of 0.5–1.0 mg.
+===Duration===
+Total Duration: 5 - 7 hours
+Onset: 15 - 30 minutes
+Come up: 15 - 30 minutes
+Peak: 2 - 3 hours
+Offset: 1.5 - 2.5 hours
+===Oral Dosage===
+Threshold: 0.1 mg
+Light: 0.25 - 0.5 mg
+Common: 0.5 - 1 mg
+Strong: 1 - 2 mg
+Heavy: 2 mg +
+'''IUPAC Name''': (2-ethyl-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
+Source: https://tripsitter.com/benzodiazepines/fluetizolam/