Rejuvenation: Difference between revisions

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~~[[category:Cognitive enhancements]]~~

'''Rejuvenation''' ~~and~~ feelings of extreme refreshment are ~~an almost universal experience in~~ the ~~days or weeks after a positive experience~~. The ~~hallucinogenic experience can be both mentally and physically invigorating. This~~ rejuvenation ~~can be described as~~ a ~~lasting feeling~~ of mental clarity, increased motivation, ~~calmness~~, and ~~an appreciation for~~ the ~~very~~ sensation of being.

'''Rejuvenation''' can be described as feelings of mild to extreme cognitive refreshment which are felt during the afterglow of certain compounds. The symptoms of rejuvenation often include a sustained sense of heightened mental clarity, increased emotional stability, increased calmness, [[mindfulness]], [[Motivation enhancement|increased motivation]], [[personal bias suppression]], [[Focus intensification|increased focus]] and [[Depression reduction|decreased depression]]. At its highest level, feelings of rejuvenation can become so intense that they manifest as the profound and overwhelming sensation of being "reborn" anew. This mindstate can potentially last anywhere from several hours to several months after the substance has worn off.

~~The effect feels as if~~ the ~~connections within the brain have been somehow restored with the biases~~ of ~~a person's perspective becoming reset to base level. It is~~ as ~~if the mind has been rebooted~~ and ~~reorganized in~~ a ~~way that fully grounds~~ the ~~revelations~~ of ~~the trip into a person's world view~~.

Rejuvination is most commonly induced under the influence of [[dosage#common|moderate]] [[dosage|dosages]] of [[hallucinogen|hallucinogenic]] compounds, such as [[psychedelic|psychedelics]] and [[dissociative|dissociatives]]. However, it can also occur to a lesser extent under the influence of [[entactogen|entactogens]], [[cannabinoid|cannabinoids]], and [[meditation]].

</onlyinclude>

~~At its highest level, the feelings~~ of ~~rejuvenation~~ can ~~become so intense~~ that ~~they begin to manifest themselves as~~ the ~~profound sensation~~ of ~~being born again. This feeling can last anywhere from weeks~~ to a ~~lifetime after the experience itself~~.

===Analysis===

There are a number of legitimate scientific studies which have concluded that long lasting mental benefits can occur after a drug has been taken. For example, it has been demonstrated that ketamine, even if taken in small doses, is effective for patients suffering from chronic depression and bipolar disorder. Studies have shown that the effect of the drug is immediate or within 2 hours and consistent in relieving a patient’s depressive and/or suicidal symptoms, lasting up to 3 days after a single dose.

A similar example includes a study which observed significantly decreased depression scores in terminal cancer patients six months after treatment with psilocybin.<ref>{{cite journal | vauthors=((Grob, C. S.)), ((Danforth, A. L.)), ((Chopra, G. S.)), ((Hagerty, M.)), ((McKay, C. R.)), ((Halberstadt, A. L.)), ((Greer, G. R.)) | journal=Archives of General Psychiatry | title=Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer | volume=68 | issue=1 | pages=71 | date=3 January 2011 | url=http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/archgenpsychiatry.2010.116 | issn=0003-990X | doi=10.1001/archgenpsychiatry.2010.116}}</ref> An open-label study was carried out in 2016 in the UK to investigate the feasibility, safety, and efficacy of psilocybin in treating patients with unipolar treatment-resistant depression with promising results; although the study was small and involved only twelve patients, seven of those patients met formal criteria for remission one week following psilocybin treatment and five of those were still in remission from their depression at three months.<ref>{{cite journal | vauthors=((Carhart-Harris, R. L.)), ((Bolstridge, M.)), ((Rucker, J.)), ((Day, C. M. J.)), ((Erritzoe, D.)), ((Kaelen, M.)), ((Bloomfield, M.)), ((Rickard, J. A.)), ((Forbes, B.)), ((Feilding, A.)), ((Taylor, D.)), ((Pilling, S.)), ((Curran, V. H.)), ((Nutt, D. J.)) | journal=The Lancet Psychiatry | title=Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study | volume=3 | issue=7 | pages=619–627 | date= July 2016 | url=https://linkinghub.elsevier.com/retrieve/pii/S2215036616300657 | issn=22150366 | doi=10.1016/S2215-0366(16)30065-7}}</ref>

===Psychoactive substances===

Compounds within our [[psychoactive substance index]] which may cause this effect include:

{{#ask:[[Category:Psychoactive substance]][[Effect::Rejuvenation]]|format=ul|Columns=2}}

===Experience reports===

Anecdotal reports which describe this effect within our [[experience index]] include:

{{#ask:[[Category:Experience]][[Effect::Rejuvenation]]|format=ul|Columns=1}}

===See also===

*[[Responsible use]]

*[[Subjective effects index]]

*[[Psychedelics#Subjective_effects|Psychedelics - Subjective effects]]

*[[Dissociatives#Subjective_effects|Dissociatives - Subjective effects]]

*[[Deliriants#Subjective_effects|Deliriants - Subjective effects]]

===References===

[[Category:Effect]]

[[Category:Cognitive]]

@@ Line 1: / Line 1: @@
-[[category:Cognitive enhancements]]
+<onlyinclude>
-'''Rejuvenation''' and feelings of extreme refreshment are an almost universal experience in the days or weeks after a positive experience. The hallucinogenic experience can be both mentally and physically invigorating. This rejuvenation can be described as a lasting feeling of mental clarity, increased motivation, calmness, and an appreciation for the very sensation of being.
+'''Rejuvenation''' can be described as feelings of mild to extreme cognitive refreshment which are felt during the afterglow of certain compounds. The symptoms of rejuvenation often include a sustained sense of heightened mental clarity, increased emotional stability, increased calmness, [[mindfulness]], [[Motivation enhancement|increased motivation]], [[personal bias suppression]], [[Focus intensification|increased focus]] and [[Depression reduction|decreased depression]]. At its highest level, feelings of rejuvenation can become so intense that they manifest as the profound and overwhelming sensation of being "reborn" anew. This mindstate can potentially last anywhere from several hours to several months after the substance has worn off.
-The effect feels as if the connections within the brain have been somehow restored with the biases of a person's perspective becoming reset to base level. It is as if the mind has been rebooted and reorganized in a way that fully grounds the revelations of the trip into a person's world view.
+Rejuvination is most commonly induced under the influence of [[dosage#common|moderate]] [[dosage|dosages]] of [[hallucinogen|hallucinogenic]] compounds, such as [[psychedelic|psychedelics]] and [[dissociative|dissociatives]]. However, it can also occur to a lesser extent under the influence of [[entactogen|entactogens]], [[cannabinoid|cannabinoids]], and [[meditation]].
+</onlyinclude>
-At its highest level, the feelings of rejuvenation can become so intense that they begin to manifest themselves as the profound sensation of being born again. This feeling can last anywhere from weeks to a lifetime after the experience itself.
+===Analysis===
+There are a number of legitimate scientific studies which have concluded that long lasting mental benefits can occur after a drug has been taken. For example, it has been demonstrated that ketamine, even if taken in small doses, is effective for patients suffering from chronic depression and bipolar disorder. Studies have shown that the effect of the drug is immediate or within 2 hours and consistent in relieving a patient’s depressive and/or suicidal symptoms, lasting up to 3 days after a single dose.
+A similar example includes a study which observed significantly decreased depression scores in terminal cancer patients six months after treatment with psilocybin.<ref>{{cite journal | vauthors=((Grob, C. S.)), ((Danforth, A. L.)), ((Chopra, G. S.)), ((Hagerty, M.)), ((McKay, C. R.)), ((Halberstadt, A. L.)), ((Greer, G. R.)) | journal=Archives of General Psychiatry | title=Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer | volume=68 | issue=1 | pages=71 | date=3 January 2011 | url=http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/archgenpsychiatry.2010.116 | issn=0003-990X | doi=10.1001/archgenpsychiatry.2010.116}}</ref> An open-label study was carried out in 2016 in the UK to investigate the feasibility, safety, and efficacy of psilocybin in treating patients with unipolar treatment-resistant depression with promising results; although the study was small and involved only twelve patients, seven of those patients met formal criteria for remission one week following psilocybin treatment and five of those were still in remission from their depression at three months.<ref>{{cite journal | vauthors=((Carhart-Harris, R. L.)), ((Bolstridge, M.)), ((Rucker, J.)), ((Day, C. M. J.)), ((Erritzoe, D.)), ((Kaelen, M.)), ((Bloomfield, M.)), ((Rickard, J. A.)), ((Forbes, B.)), ((Feilding, A.)), ((Taylor, D.)), ((Pilling, S.)), ((Curran, V. H.)), ((Nutt, D. J.)) | journal=The Lancet Psychiatry | title=Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study | volume=3 | issue=7 | pages=619–627 | date= July 2016 | url=https://linkinghub.elsevier.com/retrieve/pii/S2215036616300657 | issn=22150366 | doi=10.1016/S2215-0366(16)30065-7}}</ref>
+===Psychoactive substances===
+Compounds within our [[psychoactive substance index]] which may cause this effect include:
+{{#ask:[[Category:Psychoactive substance]][[Effect::Rejuvenation]]|format=ul|Columns=2}}
+===Experience reports===
+Anecdotal reports which describe this effect within our [[experience index]] include:
+{{#ask:[[Category:Experience]][[Effect::Rejuvenation]]|format=ul|Columns=1}}
 ===See also===
+*[[Responsible use]]
 *[[Subjective effects index]]
 *[[Psychedelics#Subjective_effects|Psychedelics - Subjective effects]]
 *[[Dissociatives#Subjective_effects|Dissociatives - Subjective effects]]
 *[[Deliriants#Subjective_effects|Deliriants - Subjective effects]]
+===References===
+<references />
+[[Category:Effect]]
+[[Category:Cognitive]]