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Heroin: Difference between revisions
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==Subjective effects== | ==Subjective effects== | ||
{{Preamble/SubjectiveEffects}} | {{Preamble/SubjectiveEffects}} | ||
{{effects/base | {{effects/base | ||
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====Hallucinatory states==== | ====Hallucinatory states==== | ||
*'''[[Effect::Internal hallucination]]''' - One may experience a state of semi-consciousness and [[hypnagogia]] during heavy dosage nodding which results in dream-like states and up to level 3 [[Lucid_dreaming#Internally_sourced_sensory_input|imagery]]. This is often accompanied by ill-defined [[geometry]]. | *'''[[Effect::Internal hallucination]]''' - One may experience a state of semi-consciousness and [[hypnagogia]] during heavy dosage nodding which results in dream-like states and up to level 3 [[Lucid_dreaming#Internally_sourced_sensory_input|imagery]]. This is often accompanied by ill-defined [[geometry]]. | ||
}} | }} | ||
{{effects/auditory| | |||
*'''[[Effect::Auditory acuity suppression]]''' | |||
*'''[[Effect::Auditory distortion]]''' - Some users experience rumbling in the ears and/or tinnitus with this substance. Effect may last for long periods after the experience due to the ototoxicity of opioids | |||
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===Experience reports=== | ===Experience reports=== | ||
Anecdotal reports which describe the effects of this compound within our [[experience index]] include: | Anecdotal reports which describe the effects of this compound within our [[experience index]] include: | ||
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It is strongly recommended that one use [[responsible drug use|harm reduction practices]] such as [[volumetric dosing]], when using this substance to ensure the administration of the intended dose (especially due to the unusually high risk of an overdose this substance presents.) | It is strongly recommended that one use [[responsible drug use|harm reduction practices]] such as [[volumetric dosing]], when using this substance to ensure the administration of the intended dose (especially due to the unusually high risk of an overdose this substance presents.) | ||
====Bodily harm==== | |||
Many opioid drugs, especially oxycodone and [[heroin]], are known to be [https://en.wikipedia.org/wiki/Ototoxicity ototoxic], causing hearing loss, tinnitus and balance issues. In some cases the damage can be irreversible.<ref>Opioid-Associated Hearing Loss: A 20-Year Review from the New Jersey Poison Center https://pubmed.ncbi.nlm.nih.gov/32468345/</ref> | |||
Opioids can cause [[Difficulty urinating|urinary retention, or difficulty urinating]] and [[constipation]] with chronic and repeated use. Some users find relief in blowing hard into their palm or doing squats before using the toilet, as this compresses core muscles onto the bladder. | |||
===Dependence and abuse potential=== | ===Dependence and abuse potential=== | ||
As with other [[opioids]], the chronic use of heroin can be considered | As with other [[opioids]], the chronic use of heroin can be considered extremely addictive with a high potential for abuse and is capable of causing psychological and physical dependence among certain users. When psychological or physical addiction has developed, mental and physical [[Opioids#Discontinuation|withdrawal symptoms]] and cravings may occur if a person suddenly stops their usage. | ||
Tolerance to many of the effects of heroin [[Time to full tolerance::develops with prolonged and repeated use]]. The rate at which this occurs develops at different rates for different effects, with tolerance to the constipation-inducing effects developing particularly slowly for instance. This results in users having to administer increasingly large doses to achieve the same psychoactive effects of a previously lower dose. After heroin tolerance has developed, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Heroin presents cross-tolerance with [[Cross-tolerance::all other [[opioids]]]], meaning that after the consumption of heroin all [[opioid]]s will have a reduced effect. | Tolerance to many of the effects of heroin [[Time to full tolerance::develops with prolonged and repeated use]]. The rate at which this occurs develops at different rates for different effects, with tolerance to the constipation-inducing effects developing particularly slowly for instance. This results in users having to administer increasingly large doses to achieve the same psychoactive effects of a previously lower dose. After heroin tolerance has developed, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Heroin presents cross-tolerance with [[Cross-tolerance::all other [[opioids]]]], meaning that after the consumption of heroin all [[opioid]]s will have a reduced effect. | ||
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*[http://en.wikipedia.org/wiki/Heroin Heroin (Wikipedia)] | *[http://en.wikipedia.org/wiki/Heroin Heroin (Wikipedia)] | ||
*[https://www.erowid.org/chemicals/heroin/heroin.shtml Heroin (Erowid Vault)] | *[https://www.erowid.org/chemicals/heroin/heroin.shtml Heroin (Erowid Vault)] | ||
*[https://isomerdesign.com/PiHKAL/explore.php?id=9295 Heroin ( | *[https://isomerdesign.com/PiHKAL/explore.php?id=9295 Heroin (Isomer Design)] | ||
*[https://go.drugbank.com/drugs/DB01452 Heroin (DrugBank)] | *[https://go.drugbank.com/drugs/DB01452 Heroin (DrugBank)] | ||
*[https://drugs-forum.com/wiki/Heroin Heroin (Drugs-Forum)] | *[https://drugs-forum.com/wiki/Heroin Heroin (Drugs-Forum)] | ||