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Talk:4-MEC: Difference between revisions
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{{headerpanel| {{ | {{decree|type=notice|message=This article is in the 'Talk' namespace because it is an unfinished draft. This section is used to host drafts for unpublished articles as well as discussions for published ones. If you'd like to use this area to discuss this draft, please do so in the 'Discussion' section at the very bottom of the page. This notice will be removed once this draft has been approved for publication by an administrator.}} | ||
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{{SummarySheet}} | {{SummarySheet}} | ||
{{SubstanceBox/4-MEC}} | {{SubstanceBox/4-MEC}} | ||
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==Pharmacology== | ==Pharmacology== | ||
{{pharmacology}} | |||
Given its chemical structure, 4-MEC is likely to act as a [[releasing agent]] and a [[reuptake inhibitor]] for monoamine [[neurotransmitters]] such as [[dopamine]], [[serotonin]] and [[noradrenaline]]. | Given its chemical structure, 4-MEC is likely to act as a [[releasing agent]] and a [[reuptake inhibitor]] for monoamine [[neurotransmitters]] such as [[dopamine]], [[serotonin]] and [[noradrenaline]]. | ||
4-MEC is likely to have a similar pharmacological profile to mephedrone. | 4-MEC is likely to have a similar pharmacological profile to mephedrone. | ||
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}} | }} | ||
|{{effects/cognitive| | |{{effects/cognitive| | ||
The cognitive effects of 4-MEC can be broken down into several components which progressively intensify proportional to dosage. The general head space of | The cognitive effects of 4-MEC can be broken down into several components which progressively intensify proportional to dosage. The general head space of 4-MEC is described by many as one of extreme mental stimulation and powerful euphoria. It contains a large number of typical [[Stimulants|stimulant]] cognitive effects. | ||
The most prominent of these cognitive effects generally include: | The most prominent of these cognitive effects generally include: | ||
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}} | }} | ||
===Experience reports=== | ===Experience reports=== | ||
There are currently | There are currently {{#ask:[[Category:SUBSTANCE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]]. | ||
{{#ask: [[Category:SUBSTANCE]][[Category:Experience]]|format=ul|Columns=1}} | |||
Additional experience reports can be found here: | |||
* [https://www.erowid.org/experiences/subs/exp_4Methylethcathinone.shtml Erowid Experience Vaults: 4-Methylethcathinone] | * [https://www.erowid.org/experiences/subs/exp_4Methylethcathinone.shtml Erowid Experience Vaults: 4-Methylethcathinone] | ||
==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
{{toxicity}} | |||
{{Further|Research chemicals#Toxicity and harm potential}} | {{Further|Research chemicals#Toxicity and harm potential}} | ||
Almost nothing is known about the long-term effects of 4-MEC due to its short history of its use. The [[Toxicity::exact toxic dosage is unknown]]. | Almost nothing is known about the long-term effects of 4-MEC due to its short history of its use. The [[Toxicity::exact toxic dosage is unknown]]. | ||
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As with other [[stimulant]]s, the chronic use of 4-MEC can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage. | As with other [[stimulant]]s, the chronic use of 4-MEC can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage. | ||
Tolerance to many of the effects of 4-MEC [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). 4-MEC presents cross-tolerance with [[Cross-tolerance::all [[dopamine]]rgic [[stimulant]]s]], meaning that after the consumption of | Tolerance to many of the effects of 4-MEC [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). 4-MEC presents cross-tolerance with [[Cross-tolerance::all [[dopamine]]rgic [[stimulant]]s]], meaning that after the consumption of 4-MEC all [[stimulant]]s will have a reduced effect. | ||
===Dangerous interactions=== | ===Dangerous interactions=== | ||
{{DangerousInteractions}} | |||
{{DangerousInteractions/Intro}} | {{DangerousInteractions/Intro}} | ||
{{DangerousInteractions/Stimulants|self=[[Substituted cathinone|cathinone]]s}} | {{DangerousInteractions/Stimulants|self=[[Substituted cathinone|cathinone]]s}} | ||
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==Legal status== | ==Legal status== | ||
{{LegalStub}} | |||
*'''France''': As a derivative of cathinone with an alkyl substitution on the phenyl group, 4-MEC is scheduled as a "stupéfiant", i.e. a recognized drug of abuse. It is illegal to possess, buy, sell or manufacture.<ref>{{Citation | title=Arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants | url=https://www.legifrance.gouv.fr/loda/id/JORFTEXT000000533085/2020-11-20/}}</ref> | |||
*'''Turkey:''' 4-MEC is a classed as drug and is illegal to possess, produce, supply, or import.<ref>Bakanlar Kurulu Kararı Karar Sayısı : 2013/4827 | https://free-ankara.org/wp-content/uploads/2017/09/BKK_2013_4827_28688.pdf</ref> | |||
*'''United Kingdom:''' It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016. <ref>http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref> | *'''United Kingdom:''' It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016. <ref>http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref> | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Articles in talk page]] | |||
[[Category:Psychoactive substance]] | [[Category:Psychoactive substance]] | ||
[[Category:Research chemical]] | [[Category:Research chemical]] | ||