Lysergamides: Difference between revisions

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[[File:Substituted_lysergamide.svg|thumb|right|250px|Substitutive structure of a ''lysergamide'']]

'''Lysergamides''' ~~are amides~~ of ~~lysergic acid~~. [[~~Lysergamides~~]] ~~can technically be classified as complex tryptamines<ref>https://en~~.~~wikipedia~~.~~org/wiki/List_of_psychedelic_drugs~~</ref>~~, like Ibogaine~~.

'''Lysergamides''' or ergoamides<ref>Jamieson CS, Misa J, Tang Y, Billingsley JM (2021-04-29). "Biosynthesis and synthetic biology of psychoactive natural products". ''Chemical Society Reviews''. '''50''' (12): 6950–7008. DOI: 10.1039/D1CS00065A. [[ISSN (identifier)|ISSN]] 0306-0012. [[PMC (identifier)|PMC]] 8217322. [[PMID (identifier)|PMID]] 33908526.

“There are three main ergot alkaloid classes, clavines, ergoamides (lysergamides), and ergopeptides, with 3 belonging to the ergoamide class.” 2.5 Lysergic acid and LSD, p. 6970</ref> are amides of lysergic acid.

Ergoline refers to a class of compounds derived from alkaloids of a group of fungi known as ''[[ergot]]'' in the ''claviceps'' genus. These compounds typically have strong [[psychedelic]] effects.

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Hydroxylation of the aromatic ring is one method of metabolizing lysergamides in humans and produces compounds with greater affinity to dopamine receptors.

They can technically be classified as complex tryptamines (like ibogaine).

==Pharmacology==

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|-

|[[1cP-LSD]]||CH2CH3||CH2CH3||C=OC3H5||CH3||[[File:1cP-LSD.svg|171px]]

|-

|[[1V-LSD]]||CH2CH3||CH2CH3||C=OC3H5||CH3||[[File:1V-LSD.svg|171px]]

|-

|[[ETH-LAD]]||CH2CH3||CH2CH3||H||CH2CH3||[[File:ETH-LAD.svg|170px]]

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[[Category:Lysergamide| ]]

@@ Line 2: / Line 2: @@
 [[File:Substituted_lysergamide.svg|thumb|right|250px|Substitutive structure of a ''lysergamide'']]
-'''Lysergamides''' are amides of lysergic acid. [[Lysergamides]] can technically be classified as complex tryptamines<ref>https://en.wikipedia.org/wiki/List_of_psychedelic_drugs</ref>, like Ibogaine.
+'''Lysergamides''' or ergoamides<ref>Jamieson CS, Misa J, Tang Y, Billingsley JM (2021-04-29). "Biosynthesis and synthetic biology of psychoactive natural products". ''Chemical Society Reviews''. '''50''' (12): 6950–7008. DOI: 10.1039/D1CS00065A. [[ISSN (identifier)|ISSN]] 0306-0012. [[PMC (identifier)|PMC]] 8217322. [[PMID (identifier)|PMID]] 33908526.
+“There are three main ergot alkaloid classes, clavines, ergoamides (lysergamides), and ergopeptides, with 3 belonging to the ergoamide class.” 2.5 Lysergic acid and LSD, p. 6970</ref> are amides of lysergic acid.
 Ergoline refers to a class of compounds derived from alkaloids of a group of fungi known as ''[[ergot]]'' in the ''claviceps'' genus. These compounds typically have strong [[psychedelic]] effects.
@@ Line 12: / Line 14: @@
 Hydroxylation of the aromatic ring is one method of metabolizing lysergamides in humans and produces compounds with greater affinity to dopamine receptors.
+They can technically be classified as complex tryptamines (like ibogaine).
 ==Pharmacology==
@@ Line 41: / Line 45: @@
 |-
 |[[1cP-LSD]]||CH<sub>2</sub>CH<sub>3</sub>||CH<sub>2</sub>CH<sub>3</sub>||C=OC<sub>3</sub>H<sub>5</sub>||CH<sub>3</sub>||[[File:1cP-LSD.svg|171px]]
+|-
+|[[1V-LSD]]||CH<sub>2</sub>CH<sub>3</sub>||CH<sub>2</sub>CH<sub>3</sub>||C=OC<sub>3</sub>H<sub>5</sub>||CH<sub>3</sub>||[[File:1V-LSD.svg|171px]]
 |-
 |[[ETH-LAD]]||CH<sub>2</sub>CH<sub>3</sub>||CH<sub>2</sub>CH<sub>3</sub>||H||CH<sub>2</sub>CH<sub>3</sub>||[[File:ETH-LAD.svg|170px]]
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 [[Category:Lysergamide| ]]
 <references />
+{{#set:Featured=true}}