5-MeO-MiPT: Difference between revisions

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==Pharmacology==

5-MeO-MiPT's [[psychedelic]] effects are believed to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT2A receptor]] as a [[Agonist#Agonists|partial agonist]<ref name="pmid17223101">{{cite journal|title=The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain|pmid=17223101|volume=559|issue=2–3|year=2007|pages=132-137|first1=F.|last1=Nagai|first2=R.|last2=Nonaka|first3=K.|last3=Satoh|first4=H.|last4=Kamimura|journal=European Journal of Pharmacology|issn=0014-2999|eissn=1879-0712|oclc=01568459|doi=10.1016/j.ejphar.2006.11.075}}</ref><ref name="Repke1985" /> and additional mechanisms of action such as the inhibition of [[MAOI|MAO]] (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically.

5-MeO-MiPT's [[psychedelic]] effects are believed to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT2A receptor]] as a [[Agonist#Agonists|partial agonist]]<ref name="pmid17223101">{{cite journal|title=The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain|pmid=17223101|volume=559|issue=2–3|year=2007|pages=132-137|first1=F.|last1=Nagai|first2=R.|last2=Nonaka|first3=K.|last3=Satoh|first4=H.|last4=Kamimura|journal=European Journal of Pharmacology|issn=0014-2999|eissn=1879-0712|oclc=01568459|doi=10.1016/j.ejphar.2006.11.075}}</ref><ref name="Repke1985" /> and additional mechanisms of action such as the inhibition of [[MAOI|MAO]] (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically. While 5-MeO-MiPT binds most strongly to 5-HT1A receptors, It might act as a moderately potent serotonin-norepinephrine reuptake inhibitor<ref>{{cite journal | vauthors=((Ray, T. S.)) | journal=PLoS ONE | title=Correction: Psychedelics and the Human Receptorome | volume=5 | issue=3 | date=4 March 2010 | url=https://dx.plos.org/10.1371/annotation/e580a864-cf13-40c2-9bd9-b9687a6f0fe4 | issn=1932-6203 | doi=10.1371/annotation/e580a864-cf13-40c2-9bd9-b9687a6f0fe4}}</ref> but other studies have not found significant action at the monoamine transporters[https://www.sciencedirect.com/science/article/abs/pii/S0924977X16300426]. These mechanisms may help explain why there are many anecdotal reports of anti-depressant and anxiolytic effects from modest doses of this compound. For example, SNRIs such as venlafaxine are commonly prescribed to treat depression, and the 5-HT1A agonist buspirone is prescribed primarily for treatment of anxiety.

==Subjective effects==

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{{effects/base

|{{effects/physical|

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*'''[[Effect::Increased music appreciation]]'''

*'''[[Effect::Emotion enhancement]]'''

*'''[[Effect::Increased libido]]'''

*'''[[Effect::Increased libido]]''' - increased libido and significantly enhanced orgasms are reported

*'''[[Effect::Memory suppression]]'''

*'''[[Effect::Novelty enhancement]]'''

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==Reagent results==

Exposing compounds to the reagents gives a colour change which is indicative of the compound under test. The following test results are from [https://www.protestkit.eu/results/ ~~protestkit~~].

Exposing compounds to the reagents gives a colour change which is indicative of the compound under test. The following test results are from [https://www.protestkit.eu/results/ ProTestKit].

{| class="wikitable"

!5-MeO-MiPT

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|-

|Freebase

|Orange to brown

|Orange - brown

|Orange red

|Deep greenish brown

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|-

|HCl

|Orange to brown

|Orange - brown

|Red to brown

|Red - brown

|Greenish brown

|Brown

|Violet to purple

|Violet - purple

|Green

|Unknown

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==Toxicity and harm potential==

{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}

~~The toxicity and~~ long-term ~~health~~ effects of ~~recreational~~ 5-MeO-MiPT ~~do not seem to have been studied in any scientific context and~~ the exact ~~[[Toxicity::~~toxic ~~dose~~ is unknown]]. This is because 5-MeO-MiPT is a [[research chemical]] with very little history of human ~~usage~~.

Almost nothing is known about the long-term effects of 5-MeO-MiPT. Alongside of this, the exact toxic dosage is unknown. This is because 5-MeO-MiPT is a [[research chemical]] with very little history of human use.

A preliminary study on mice has shown that a normal dose of 5-MeO-MiPT (0.27 mg/kg) was unable to produce any measurable toxic effects.<ref name=":0">Altuncı YA, Aydoğdu M, Açıkgöz E, Güven Ü, Düzağaç F, Atasoy A, Dağlıoğlu N, Annette Akgür S. [https://pubmed.ncbi.nlm.nih.gov/32936075/ New Psychoactive Substance 5-MeO-MiPT In vivo Acute Toxicity and Hystotoxicological Study.] Balkan Med J. 2021 Jan;38(1):34-42. [[wikipedia:Digital_object_identifier|doi]]:[https://doi.org/10.4274/balkanmedj.galenos.2020.2019.11.68 10.4274/balkanmedj.galenos.2020.2019.11.68] [[wikipedia:PubMed_Identifier|PMID]]: [https://pubmed.ncbi.nlm.nih.gov/32936075/ 32936075]; [https://en.wikipedia.org/wiki/PubMed_Central#PMCID PMCID]: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8909217/ PMC8909217].

</ref> However, doses of 5-MeO-MiPT way above the normal dosage range (2.7 mg/kg) have been shown to produce cell toxicity by triggering programmed cell death in the brain, liver and kidneys. The extent of the damage, if it occurs in other bodily tissues as well and how it is caused is not known yet.

Anecdotal evidence from people within the community who have tried 5-MeO-MiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption.

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==Legal status==

*'''Austria''': 5-MeO-MiPT is illegal to possess, produce and sell under the NPSG (''Neue Psychoaktive Substanzen Gesetz'').<ref>[https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=20007605 Gesamte Rechtsvorschrift für Neue-Psychoaktive-Substanzen-Gesetz] ''(in german). Bundeskriminalamt Österreich. Retrieved April 13, 2023.''</ref> However, offenders with no intent to distribute will likely not have to face prosecution.

*'''Brazil''': 5-MeO-MiPT is illegal to produce, sell, or possess as it is listed on Portaria SVS/MS nº 344.<ref>{{cite web|url=http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7|title=RESOLUÇÃO DA DIRETORIA COLEGIADA - RDC N° 130, DE 2 DE DEZEMBRO DE 2016|publication-date=December 5, 2016|publisher=Agência Nacional de Vigilância Sanitária (ANVISA) [Brazilian Health Regulatory Agency (ANVISA)]|language=pt}}</ref>

*'''China''': 5-MeO-MiPT is controlled as a Category I psychotropic substance and is illegal to sell, buy, import, export, and manufacture.<ref>{{cite web|title=Erowid China Psychoactive Law Update: September 2015|url=https://www.erowid.org/psychoactives/law/countries/china/china_law_2015_09_27_list_of_newly_controlled_chemicals.pdf|access-date=September 29, 2020|publisher=Erowid}}</ref>

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*'''Japan''': 5-MeO-MiPT is controlled as a "Designated Substance" (Shitei-Yakubutsu) by the Pharmaceutical Affairs Law, making it illegal to possess or sell.{{citation needed}}

*'''Latvia''': 5-MeO-MiPT is a Schedule I drug in Latvia.<ref>{{cite web|url=http://likumi.lv/doc.php?id=121086|title=Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem|publisher=VSIA Latvijas Vēstnesis|access-date=January 1, 2020|publication-date=November 10, 2005|language=lv}}</ref>

*'''Luxembourg''': 5-MeO-MiPT is not cited in the list of prohibited substances<ref>Loi du 19 février 1973 concernant la vente de substances médicamenteuses et la lutte contre la toxicomanie. | ~~http~~://legilux.public.lu/eli/etat/leg/loi/1973/02/19/n1/jo</ref>. Therefore, it is still a legal substance.

*'''Luxembourg''': 5-MeO-MiPT is not cited in the list of prohibited substances<ref>{{Citation | title=Loi du 19 février 1973 concernant la vente de substances médicamenteuses et la lutte contre la toxicomanie. | url=https://legilux.public.lu/eli/etat/leg/loi/1973/02/19/n1/jo}}</ref>. Therefore, it is still a legal substance.

*'''New Zealand''': 5-MeO-MiPT is an analogue of DMT which makes it a Class C controlled drug in New Zealand.<ref>{{cite web|url=http://www.legislation.govt.nz/act/public/1975/0116/latest/whole.html#DLM436576|title=Schedule 1: Class A controlled drugs|access-date=September 19, 2020|work=Misuse of Drugs Act 1975|publisher=Parliamentary Counsel Office (PCO)}}</ref>

*'''Romania''': 5-MeO-MiPT and other derivatives are illegal in Romania, as of January 2011.{{citation needed}}

*'''Switzerland''': 5-MeO-MiPT is a controlled substance specifically named under Verzeichnis E.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>

*'''Turkey:''' 5-MeO-MiPT is classed as a drug and is illegal to possess, produce, supply, or import.<ref>Bakanlar Kurulu Kararı Karar Sayısı : 2013/4827 | https://free-ankara.org/wp-content/uploads/2017/09/BKK_2013_4827_28688.pdf</ref>

*'''United Kingdom''': 5-MeO-MiPT is a Class A drug in the UK as it is an ether of the drug 5-HO-MiPT, which is a Class A drug as a result of the tryptamine catch-all clause.<ref>{{cite web|title=Schedule 2: Part I: Class A Drugs|url=http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I|work="Misuse of Drugs Act 1971"|access-date=August 20, 2020|publisher=UK Government}}</ref>

*'''United States''': 5-MeO-MiPT is unscheduled in the United States. It may be considered an analogue of [[5-MeO-DiPT]], a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.~~{{citation needed}}~~

*'''United States''': 5-MeO-MiPT is unscheduled in the United States. It may be considered an analogue of [[5-MeO-DiPT]], a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.<ref>https://www.law.cornell.edu/uscode/text/21/813</ref>

**'''Florida''': 5-MeO-MiPT is a Schedule I drug in Florida.<ref>{{cite web|title=The 2015 Florida Statutes - Chapter 893|url=http://leg.state.fl.us/statutes/index.cfm?App_mode=Display_Statute&URL=0800-0899/0893/0893.html|publisher=The Florida Legislature|access-date=July 18, 2020}}</ref>

**'''Louisiana''': 5-MeO-MiPT is a Schedule I drug (as of June 2013).<ref>{{cite web|title=5-MeO-MIPT: Legal Status|publisher=Erowid|url=https://www.erowid.org/chemicals/5meo_mipt/5meo_mipt_law.shtml|date=July 7, 2005|access-date=September 29, 2020}}</ref>

@@ Line 17: / Line 17: @@
 ==Pharmacology==
 {{Further|Serotonergic psychedelic}}
--MeO-MiPT's [[psychedelic]] effects are believed to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT<sub>2A</sub> receptor]] as a [[Agonist#Agonists|partial agonist]<ref name="pmid17223101">{{cite journal|title=The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain|pmid=17223101|volume=559|issue=2–3|year=2007|pages=132-137|first1=F.|last1=Nagai|first2=R.|last2=Nonaka|first3=K.|last3=Satoh|first4=H.|last4=Kamimura|journal=European Journal of Pharmacology|issn=0014-2999|eissn=1879-0712|oclc=01568459|doi=10.1016/j.ejphar.2006.11.075}}</ref><ref name="Repke1985" /> and additional mechanisms of action such as the inhibition of [[MAOI|MAO]] (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically.
+-MeO-MiPT's [[psychedelic]] effects are believed to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT<sub>2A</sub> receptor]] as a [[Agonist#Agonists|partial agonist]]<ref name="pmid17223101">{{cite journal|title=The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain|pmid=17223101|volume=559|issue=2–3|year=2007|pages=132-137|first1=F.|last1=Nagai|first2=R.|last2=Nonaka|first3=K.|last3=Satoh|first4=H.|last4=Kamimura|journal=European Journal of Pharmacology|issn=0014-2999|eissn=1879-0712|oclc=01568459|doi=10.1016/j.ejphar.2006.11.075}}</ref><ref name="Repke1985" /> and additional mechanisms of action such as the inhibition of [[MAOI|MAO]] (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically. While 5-MeO-MiPT binds most strongly to 5-HT1A receptors, It might act as a moderately potent serotonin-norepinephrine reuptake inhibitor<ref>{{cite journal | vauthors=((Ray, T. S.)) | journal=PLoS ONE | title=Correction: Psychedelics and the Human Receptorome | volume=5 | issue=3 | date=4 March 2010 | url=https://dx.plos.org/10.1371/annotation/e580a864-cf13-40c2-9bd9-b9687a6f0fe4 | issn=1932-6203 | doi=10.1371/annotation/e580a864-cf13-40c2-9bd9-b9687a6f0fe4}}</ref> but other studies have not found significant action at the monoamine transporters[https://www.sciencedirect.com/science/article/abs/pii/S0924977X16300426]. These mechanisms may help explain why there are many anecdotal reports of anti-depressant and anxiolytic effects from modest doses of this compound. For example, SNRIs such as venlafaxine are commonly prescribed to treat depression, and the 5-HT1A agonist buspirone is prescribed primarily for treatment of anxiety.
 ==Subjective effects==
@@ Line 23: / Line 23: @@
 {{Preamble/SubjectiveEffects}}
 {{effects/base
 |{{effects/physical|
@@ Line 76: / Line 77: @@
 *'''[[Effect::Increased music appreciation]]'''
 *'''[[Effect::Emotion enhancement]]'''
-*'''[[Effect::Increased libido]]'''
+*'''[[Effect::Increased libido]]''' - increased libido and significantly enhanced orgasms are reported
 *'''[[Effect::Memory suppression]]'''
 *'''[[Effect::Novelty enhancement]]'''
@@ Line 100: / Line 101: @@
 ==Reagent results==
-Exposing compounds to the reagents gives a colour change which is indicative of the compound under test. The following test results are from [https://www.protestkit.eu/results/ protestkit].
+Exposing compounds to the reagents gives a colour change which is indicative of the compound under test. The following test results are from [https://www.protestkit.eu/results/ ProTestKit].
 {| class="wikitable"
 !5-MeO-MiPT
@@ Line 112: / Line 113: @@
 |-
 |Freebase
-|Orange to brown
+|Orange - brown
 |Orange red
 |Deep greenish brown
@@ Line 121: / Line 122: @@
 |-
 |HCl
-|Orange to brown
+|Orange - brown
-|Red to brown
+|Red - brown
 |Greenish brown
 |Brown
-|Violet to purple
+|Violet - purple
 |Green
 |Unknown
@@ Line 132: / Line 133: @@
 ==Toxicity and harm potential==
 {{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
-The toxicity and long-term health effects of recreational 5-MeO-MiPT do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because 5-MeO-MiPT is a [[research chemical]] with very little history of human usage.
+Almost nothing is known about the long-term effects of 5-MeO-MiPT. Alongside of this, the exact toxic dosage is unknown. This is because 5-MeO-MiPT is a [[research chemical]] with very little history of human use.
+A preliminary study on mice has shown that a normal dose of 5-MeO-MiPT (0.27 mg/kg) was unable to produce any measurable toxic effects.<ref name=":0">Altuncı YA, Aydoğdu M, Açıkgöz E, Güven Ü, Düzağaç F, Atasoy A, Dağlıoğlu N, Annette Akgür S. [https://pubmed.ncbi.nlm.nih.gov/32936075/ New Psychoactive Substance 5-MeO-MiPT In vivo Acute Toxicity and Hystotoxicological Study.] Balkan Med J. 2021 Jan;38(1):34-42. [[wikipedia:Digital_object_identifier|doi]]:[https://doi.org/10.4274/balkanmedj.galenos.2020.2019.11.68 10.4274/balkanmedj.galenos.2020.2019.11.68] [[wikipedia:PubMed_Identifier|PMID]]: [https://pubmed.ncbi.nlm.nih.gov/32936075/ 32936075]; [https://en.wikipedia.org/wiki/PubMed_Central#PMCID PMCID]: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8909217/ PMC8909217].
+<br /></ref> However, doses of 5-MeO-MiPT way above the normal dosage range (2.7 mg/kg) have been shown to produce cell toxicity by triggering programmed cell death in the brain, liver and kidneys. The extent of the damage, if it occurs in other bodily tissues as well and how it is caused is not known yet.
 Anecdotal evidence from people within the community who have tried 5-MeO-MiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption.
@@ Line 150: / Line 155: @@
 ==Legal status==
+*'''Austria''': 5-MeO-MiPT is illegal to possess, produce and sell under the NPSG (''Neue Psychoaktive Substanzen Gesetz'').<ref>[https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=20007605 Gesamte Rechtsvorschrift für Neue-Psychoaktive-Substanzen-Gesetz] ''(in german). Bundeskriminalamt Österreich. Retrieved April 13, 2023.''</ref> However, offenders with no intent to distribute will likely not have to face prosecution.
 *'''Brazil''': 5-MeO-MiPT is illegal to produce, sell, or possess as it is listed on Portaria SVS/MS nº 344.<ref>{{cite web|url=http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7|title=RESOLUÇÃO DA DIRETORIA COLEGIADA - RDC N° 130, DE 2 DE DEZEMBRO DE 2016|publication-date=December 5, 2016|publisher=Agência Nacional de Vigilância Sanitária (ANVISA) [Brazilian Health Regulatory Agency (ANVISA)]|language=pt}}</ref>
 *'''China''': 5-MeO-MiPT is controlled as a Category I psychotropic substance and is illegal to sell, buy, import, export, and manufacture.<ref>{{cite web|title=Erowid China Psychoactive Law Update: September 2015|url=https://www.erowid.org/psychoactives/law/countries/china/china_law_2015_09_27_list_of_newly_controlled_chemicals.pdf|access-date=September 29, 2020|publisher=Erowid}}</ref>
@@ Line 156: / Line 162: @@
 *'''Japan''': 5-MeO-MiPT is controlled as a "Designated Substance" (Shitei-Yakubutsu) by the Pharmaceutical Affairs Law, making it illegal to possess or sell.{{citation needed}}
 *'''Latvia''': 5-MeO-MiPT is a Schedule I drug in Latvia.<ref>{{cite web|url=http://likumi.lv/doc.php?id=121086|title=Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem|publisher=VSIA Latvijas Vēstnesis|access-date=January 1, 2020|publication-date=November 10, 2005|language=lv}}</ref>
-*'''Luxembourg''': 5-MeO-MiPT is not cited in the list of prohibited substances<ref>Loi du 19 février 1973 concernant la vente de substances médicamenteuses et la lutte contre la toxicomanie. | http://legilux.public.lu/eli/etat/leg/loi/1973/02/19/n1/jo</ref>. Therefore, it is still a legal substance.
+*'''Luxembourg''': 5-MeO-MiPT is not cited in the list of prohibited substances<ref>{{Citation | title=Loi du 19 février 1973 concernant la vente de substances médicamenteuses et la lutte contre la toxicomanie. | url=https://legilux.public.lu/eli/etat/leg/loi/1973/02/19/n1/jo}}</ref>. Therefore, it is still a legal substance.
 *'''New Zealand''': 5-MeO-MiPT is an analogue of DMT which makes it a Class C controlled drug in New Zealand.<ref>{{cite web|url=http://www.legislation.govt.nz/act/public/1975/0116/latest/whole.html#DLM436576|title=Schedule 1: Class A controlled drugs|access-date=September 19, 2020|work=Misuse of Drugs Act 1975|publisher=Parliamentary Counsel Office (PCO)}}</ref>
 *'''Romania''': 5-MeO-MiPT and other derivatives are illegal in Romania, as of January 2011.{{citation needed}}
 *'''Switzerland''': 5-MeO-MiPT is a controlled substance specifically named under Verzeichnis E.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>
+*'''Turkey:''' 5-MeO-MiPT is classed as a drug and is illegal to possess, produce, supply, or import.<ref>Bakanlar Kurulu Kararı Karar Sayısı : 2013/4827 | https://free-ankara.org/wp-content/uploads/2017/09/BKK_2013_4827_28688.pdf</ref>
 *'''United Kingdom''': 5-MeO-MiPT is a Class A drug in the UK as it is an ether of the drug 5-HO-MiPT, which is a Class A drug as a result of the tryptamine catch-all clause.<ref>{{cite web|title=Schedule 2: Part I: Class A Drugs|url=http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I|work="Misuse of Drugs Act 1971"|access-date=August 20, 2020|publisher=UK Government}}</ref>
-*'''United States''': 5-MeO-MiPT is unscheduled in the United States. It may be considered an analogue of [[5-MeO-DiPT]], a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.{{citation needed}}
+*'''United States''': 5-MeO-MiPT is unscheduled in the United States. It may be considered an analogue of [[5-MeO-DiPT]], a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.<ref>https://www.law.cornell.edu/uscode/text/21/813</ref>
 **'''Florida''': 5-MeO-MiPT is a Schedule I drug in Florida.<ref>{{cite web|title=The 2015 Florida Statutes - Chapter 893|url=http://leg.state.fl.us/statutes/index.cfm?App_mode=Display_Statute&URL=0800-0899/0893/0893.html|publisher=The Florida Legislature|access-date=July 18, 2020}}</ref>
 **'''Louisiana''': 5-MeO-MiPT is a Schedule I drug (as of June 2013).<ref>{{cite web|title=5-MeO-MIPT: Legal Status|publisher=Erowid|url=https://www.erowid.org/chemicals/5meo_mipt/5meo_mipt_law.shtml|date=July 7, 2005|access-date=September 29, 2020}}</ref>