Dosage classification: Difference between revisions

>Oskykins
Created page with "__NOTOC__ Although different substances induce different effects regardless of their appropriate dosage, the intensity of the experience they are likely to induce can be broke..."
 
>David Hedlund
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__NOTOC__
<onlyinclude>The range and intensity of the effects of a substance depends on upon a number of factors. These include [[route of administration]], [[dosage]], [[set and setting]], and personal and environmental factors.  
Although different substances induce different effects regardless of their appropriate dosage, the intensity of the experience they are likely to induce can be broken down into five separate categories.


The effects below should not to be considered as fact and should therefore be used merely as a general guideline. These effects will almost certainly differ between specific compounds and further research must be done beyond this article to determine their individual dosages, [[duration]]s and [[subjective effect index|subjective effects]].
Effective doses can be divided into five categories: '''threshold''', '''light''', '''common''', '''strong''', and '''heavy'''.</onlyinclude>
=== '''Microdose''' ===
A microdose is a sub-perceptual dose which is so low (such as 10 micrograms of LSD) that it is unlikely to induce directly noticeable or perceptible effects.


The panels below demonstrate which effects generally occur at a [[Dosage#Microdose|microdose]] dose for various classes of psychoactive substances.
==Types==
<div class='flex-panel'>
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel">[[Psychedelic]]s [[File:eye.svg|x20px|right|link=]]</h3>         
            <ul class="featured-table">
                <li class="featured list-item">
<h4 class="media-heading">Visual</h4>
*'''[[Visual enhancements|Enhancements]]''' (''sub-perceptual'')
                </li>
                <li class="featured list-item">
                    <h4 class="media-heading">Other</h4>
*'''[[Analysis enhancement]]''' (''sub-perceptual'')
*'''[[Conceptual thinking]]''' (''sub-perceptual'')
*'''[[Creativity enhancement]]''' (''sub-perceptual'')
*'''[[Emotion enhancement]]''' (''sub-perceptual'')
*'''[[Novelty enhancement]]''' (''sub-perceptual'')</li>
*'''[[Spirituality enhancement]]''' (''sub-perceptual'')
            </ul>
        </div>


        <div class="panel radius">
===Threshold===
            <h3 class="panel">[[Dissociative]]s [[File:Chain-broken.svg|x20px|right|link=]]</h3>
A threshold dose is the dose at which the mental and physical alterations produced by the substance first become apparent.
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''sub-perceptual'')
*'''[[Cognitive euphoria]]''' (''sub-perceptual'')
*'''[[Depersonalization]]''' (''sub-perceptual'')
*'''[[Derealization]]''' (''sub-perceptual'')
            </ul>
        </div>
    </div>


    <div class='flex-column'>
These effects are distinctly beyond that of placebo but may still be ignored with some effort by directing one's focus towards the external environment.  
        <div class="panel radius">
            <h3 class="panel">[[Stimulant]]s [[File:Arrow-up.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Focus enhancement]]''' (''sub-perceptual'')
*'''[[Stimulation]]''' (''sub-perceptual'')
*'''[[Thought acceleration]]''' (''sub-perceptual'')
*'''[[Wakefulness]]''' (''sub-perceptual'')
            </ul>
        </div>


        <div class="panel radius">
Subjects may perceive a vague sense of "something" or anticipatory energy building up in the background at this level.
            <h3 class="panel">[[Cannabis]] [[File:Cannabis_leaf_%281%29.svg|x23px|right|link=]]</h3>


            <ul class="featured-table">
In the context of psychedelics, a threshold dose taken for the purpose of enhancing creativity or motivation without intoxicating the subject is known as a "microdose".
                <li class="featured list-item">
*'''[[Conceptual thinking]]''' (''sub-perceptual'')
*'''[[Sedation]]''' or '''[[stimulation]]''' (''sub-perceptual'') (depending on the strain)
*'''[[Thought connectivity]]''' (''sub-perceptual'')
*'''[[Thought deceleration]]''' (''sub-perceptual'')
                </li>
            </ul>
        </div>
    </div>


    <div class='flex-column'>
===Light===
        <div class="panel radius">
A light dose produces a state which is somewhat distinct from sobriety but does not threaten to override the subject's ordinary awareness.
            <h3 class="panel">[[Benzodiazepine]]s [[File:McCormick Pills.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''sub-perceptual'')
            </ul>
        </div>


        <div class="panel radius">
The effects can be ignored by increasing the focus one directs towards the external environment and performing complex tasks.  
            <h3 class="panel-header">[[Opioid]]s [[File:Syringe-icon.png|x20px|right|link=]]</h3>


            <ul class="featured-table">
The subject may have to pay particular attention for the substance's effects to be perceptible, or they may be slightly noticeable but will not insist upon the subject's attention.
                <li class="featured list-item">
*'''[[Pain relief]]''' (''sub-perceptual'')
                </li>
            </ul>
        </div>
    </div>
</div>


==='''Threshold'''===
===Common===
A threshold dose will cause users to experience the effects of the substance in an extremely light and subtle manner which can potentially go completely unnoticed. It is distinctly just beyond that of placebo effect, but can be ignored with minimal effort when one directs their focus towards the external environment. Users may perceive a vague sense of "something" occurring at this level, but it can be challenging to distinguish it from the placebo effect. Experienced users may be able to more clearly distinguish the "something."
A common dose is the dose at which the effects and nature of the substance is quite clear and distinct; the subject's ordinary awareness slips and ignoring its action becomes difficult.  


The panels below demonstrate which effects generally occur at a [[Dosage#Threshold|threshold]] dose for various classes of psychoactive substances.
The subject will generally be able to partake in regular behaviors and remain functional and able to communicate, although this can depend on the individual.  
<div class='flex-panel'>
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel">[[Psychedelic]]s [[File:eye.svg|x20px|right|link=]]</h3>         
            <ul class="featured-table">
                <li class="featured list-item">
<h4 class="media-heading">Visual</h4>
*'''[[Geometry]]''' (''subtle'') (level [[Geometry#1._Visual_Noise|1]] - [[Geometry#2._Motion_and_Colour|2]])
*'''[[Pattern recognition enhancement]]''' (''subtle'')
*'''[[Symmetrical texture repetition]]''' (''subtle'')
*'''[[Tracers]]''' (''subtle'')
*'''[[Visual distortions]]''' (''subtle'')
*'''[[Visual enhancements]]''' (''subtle'')
                </li>
                <li class="featured list-item">
                    <h4 class="media-heading">Other</h4>
*'''[[Analysis enhancement]]''' (''subtle'')
*'''[[Conceptual thinking]]''' (''subtle'')
*'''[[Creativity enhancement]]''' (''subtle'')
*'''[[Emotion enhancement]]''' (''subtle'')
*'''[[Novelty enhancement]]''' (''subtle'')</li>
            </ul>
        </div>


        <div class="panel radius">
The effects can be allowed to occupy a predominant role or they may be suppressed and made secondary to other chosen activities with sufficient effort or in case of an emergency.
            <h3 class="panel">[[Dissociative]]s [[File:Chain-broken.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''subtle'')
*'''[[Cognitive euphoria]]''' (''subtle'')
*'''[[Depersonalization]]''' (''subtle'')
*'''[[Derealization]]''' (''subtle'')
*'''[[Pain relief]]''' (''subtle'')
            </ul>
        </div>
    </div>


    <div class='flex-column'>
===Strong===
        <div class="panel radius">
A strong dose renders its subject mostly incapable of functioning, interacting normally, or thinking in a straightforward manner.
            <h3 class="panel">[[Stimulant]]s [[File:Arrow-up.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Focus enhancement]]''' (''subtle'')
*'''[[Stimulation]]''' (''subtle'')
*'''[[Thought acceleration]]''' (''subtle'')
*'''[[Wakefulness]]''' (''subtle'')
            </ul>
        </div>


        <div class="panel radius">
The effects of the substance are clear and can no longer be ignored or suppressed, leaving the subject entirely engaged in the experience regardless of their desire or volition. Negative effects become more common at this level.  
            <h3 class="panel">[[Cannabis]] [[File:Cannabis_leaf_%281%29.svg|x23px|right|link=]]</h3>


            <ul class="featured-table">
As subjects are not able to alter the trajectory of their behavior at strong doses, it is vital that they have prepared their environment and activities in advance as well as taken any precautionary measures.
                <li class="featured list-item">
*'''[[Anxiety]]''' (''subtle'')
*'''[[Conceptual thinking]]''' (''subtle'')
*'''[[Nausea suppression]]''' (''subtle'')
*'''[[Pain relief]]''' (''subtle'')
*'''[[Paranoia]]''' (''subtle'')
*'''[[Sedation]]''' or '''[[stimulation]]''' (''subtle'') (depending on the strain)
*'''[[Thought connectivity]]''' (''subtle'')
*'''[[Thought deceleration]]''' (''subtle'')
                </li>
            </ul>
        </div>
    </div>


    <div class='flex-column'>
===Heavy===
        <div class="panel radius">
A heavy dose is the upper limit of what a substance is capable of producing in terms of psychoactive effects; doses past this range are associated with rapidly increasing side effects and marginal desirable effects.
            <h3 class="panel">[[Benzodiazepine]]s [[File:McCormick Pills.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''subtle'')
            </ul>
        </div>


        <div class="panel radius">
Depending on the substance consumed, the user may be rendered incapable of functioning and communicating in addition to experiencing extremely uncomfortable side effects that overshadow the positive effects experienced at lower doses.  
            <h3 class="panel-header">[[Opioid]]s [[File:Syringe-icon.png|x20px|right|link=]]</h3>


            <ul class="featured-table">
It is absolutely vital to employ [[harm reduction]] measures with heavy doses as the user will likely be unable to properly take care of themselves in the event of an emergency. [[Trip sitters]] are strongly advised.  
                <li class="featured list-item">
*'''[[Pain relief]]''' (''subtle'')
*'''[[Physical euphoria|Physical]]''' and '''[[cognitive euphoria]]''' (''subtle'')
                </li>
            </ul>
        </div>
    </div>
</div>
===='''Light'''====
A light dose will cause effects which are noticeable and clearly distinct from sobriety, but remain in the background of the user's perception. The effects remain possible to ignore by increasing the focus one directs towards other things when performing complex tasks. The user may have to pay particular attention to the effects of the drug for them to be recognizable, or they may be slightly noticeable but will not insist upon the user's attention.


The panels below demonstrate which effects generally occur at a [[Dosage#Light|light]] dose for various classes of psychoactive substances.
Users should also be aware that the line between a heavy dose and overdose is often very blurry and they are placing themselves at a significantly higher risk of injury, hospitalization, and death whenever they choose to take a heavy dose.  
<div class='flex-panel'>
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Psychedelic]]s [[File:eye.svg|x20px|right|link=]]</h3>
            <ul class="featured-table">
                <li class="featured list-item">
<h4 class="media-heading">Visual</h4>
*'''[[Geometry]]''' (''subtle'') (level [[Geometry#2._Motion_and_Colour|2]] - [[Geometry#3._Partially_Defined_Geometry|3]])
*'''[[Pattern recognition enhancement]]''' (''subtle'')
*'''[[Symmetrical texture repetition]]''' (''subtle'')
*'''[[Tracers]]''' (''subtle'')
*'''[[Visual distortions]]''' (''distinct'')
*'''[[Visual enhancements]]''' (''distinct'')
                <li class="featured list-item">
                    <h4 class="media-heading">Other</h4>
*'''[[Analysis enhancement]]''' (''subtle'')
*'''[[Auditory enhancement]]s''' (''distinct'')
*'''[[Conceptual thinking]]''' (''subtle'')
*'''[[Creativity enhancement]]''' (''distinct'')
*'''[[Emotion enhancement]]''' (''distinct'')
*'''[[Memory suppression|Partial short-term memory suppression]]''' (''subtle'')
*'''[[Novelty enhancement]]''' (''subtle'')
*'''[[Personal bias suppression]]''' (''subtle'')
*'''[[Spiritual states]]''' (''subtle'')
*'''[[Wakefulness]]''' (''distinct'')
            </ul>
        </div>


        <div class="panel radius">
The desire or compulsion to regularly take heavy doses ("chronic use") may also be an indicator of tolerance, addiction or other mental health problems.
            <h3 class="panel-header">[[Dissociative]]s [[File:Chain-broken.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''distinct'')
*'''[[Cognitive euphoria]]''' (''distinct'')
*'''[[Consciousness disconnection]]''' (distinct)
*'''[[Depersonalization]]''' (''distinct'')
*'''[[Derealization]]''' (''distinct'')
*'''[[Pain relief]]''' (''distinct'')
*'''[[Tactile disconnection]]''' (distinct)
*'''[[Visual disconnection]]''' (distinct)
            </ul>
        </div>
    </div>


    <div class='flex-column'>
===Overdose===
        <div class="panel radius">
An overdose is a quantity greater than recommended, intended or generally practiced, with the possibility of the dose resulting in serious injury or death.
            <h3 class="panel">[[Stimulant]]s [[File:Arrow-up.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Analysis enhancement]]''' (''distinct'')
*'''[[Appetite suppression]]''' (''subtle'')
*'''[[Euphoria]]''' (''subtle'')
*'''[[Focus enhancement]]''' (''distinct'')
*'''[[Stimulation]]''' (''subtle'')
*'''[[Thought acceleration]]''' (''subtle'')
*'''[[Wakefulness]]''' (''distinct'')
            </ul>
        </div>


        <div class="panel radius">
Immediate professional medical advice should always be sought when a user has taken a dose greater than or equal to this: although tolerance may allow experienced users' bodies to survive such doses, medical attention should still be sought in order to ensure one has not suffered severe harm.  
            <h3 class="panel">[[Cannabis]] [[File:Cannabis_leaf_%281%29.svg|x23px|right|link=]]</h3>


            <ul class="featured-table">
It should be noted that doses below this level may also be harmful in some cases. </onlyinclude>
                <li class="featured list-item">
*'''[[Anxiety]]''' (''subtle'')
*'''[[Appetite enhancement]]''' (''subtle'')
*'''[[Conceptual thinking]]''' (''subtle'')
*'''[[Memory suppression|Partial short-term memory loss]]''' (''distinct'')
*'''[[Nausea suppression]]''' (''distinct'')
*'''[[Pain relief]]''' (''distinct'')
*'''[[Paranoia]]''' (''subtle'')
*'''[[Physical euphoria]]''' (''subtle'')
*'''[[Sedation]]''' or '''[[stimulation]]''' (''distinct'') (depending on the strain)
*'''[[Thought connectivity]]''' (''distinct'')
*'''[[Thought deceleration]]''' (''distinct'')
                </li>
            </ul>
        </div>
    </div>


    <div class='flex-column'>
==See also==
        <div class="panel radius">
            <h3 class="panel">[[Benzodiazepine]]s [[File:McCormick Pills.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''distinct'')
*'''[[Muscle relaxation]]''' (''subtle'')
*'''[[Disinhibition]]''' (''subtle'')
            </ul>
        </div>


        <div class="panel radius">
*[[Responsible use]]
            <h3 class="panel">[[Opioid]]s [[File:Syringe-icon.png|x20px|right|link=]]</h3>
*[[Set and setting]]
*[[Dosage measurement]]
*[[Routes of administration]]


            <ul class="featured-table">
==External links==
                <li class="featured list-item">
*'''[[Pain relief]]''' (''distinct'')
*'''[[Physical euphoria|Physical]]''' and '''[[cognitive euphoria]]''' (''subtle'')
*'''[[Itchiness]]''' (''subtle'')
                </li>
            </ul>
        </div>
    </div>
</div>


==='''Common'''===
*[https://en.wikipedia.org/wiki/Dosing Dosing (Wikipedia)]
Within this range, not only are the effects and the nature of a drug's action quite clear and distinct, but ignoring its action becomes difficult (although experienced users may be able to do so). The user will generally  be able to partake in regular behaviors and remain functional and communicable. The effects can be allowed a predominant role or they may be repressed and made secondary to other chosen activities.
*[https://en.wikipedia.org/wiki/Drug_overdose Drug overdose (Wikipedia)]
*[https://erowid.org/psychoactives/dose/dose.shtml Dose (Erowid)]


The panels below demonstrate which effects generally occur at a [[Dosage#Common|common]] dose for various classes of psychoactive substances.
==References==
<div class='flex-panel'>
{{references}}
    <div class='flex-column'>
{{Template:Responsible use2}}
        <div class="panel radius">
[[Category:Responsible drug use]]
            <h3 class="panel-header">[[Psychedelic]]s [[File:eye.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
<h4 class="media-heading">Visual effects</h4>
*'''[[Geometry]]''' (''distinct'') (level [[Geometry#3._Partially_Defined_Geometry|3]] - [[Geometry#5._3-Dimensional_Geometry|5]])
*'''[[Pattern recognition enhancement]]''' (''distinct'')
*'''[[Symmetrical texture repetition]]''' (''distinct'')
*'''[[Tracers]]''' (''distinct'')
*'''[[Transformations]]''' (''distinct'')
*'''[[Visual distortions]]''' (''distinct'')
*'''[[Visual enhancements]]''' (''distinct'')
                <li class="featured list-item">
                    <h4 class="media-heading">Other</h4>
*'''[[Analysis enhancement]]''' (''distinct'')
*'''[[Auditory enhancement]]s''' (''distinct'')
*'''[[Conceptual thinking]]''' (''distinct'')
*'''[[Creativity enhancement]]''' (''distinct'')
*'''[[Emotion enhancement]]''' (''distinct'')
*'''[[Memory suppression|Partial to complete short-term memory suppression]]''' (''distinct'')
*'''[[Novelty enhancement]]''' (''distinct'')
*'''[[Personal bias suppression]]''' (''distinct'')
*'''[[Spiritual states]]''' (''distinct'')
*'''[[Wakefulness]]''' (''strong'')
            </ul>
        </div>


        <div class="panel radius">
{{#set:Featured=true}}
            <h3 class="panel-header">[[Dissociative]]s [[File:Chain-broken.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''distinct'')
*'''[[Cognitive euphoria]]''' (''distinct'')
*'''[[Consciousness disconnection]]''' (''distinct'')
*'''[[Depersonalization]]''' (''distinct'')
*'''[[Derealization]]''' (''distinct'')
*'''[[Pain relief]]''' (''distinct'')
*'''[[Tactile disconnection]]''' (''distinct'')
*'''[[Visual disconnection]]''' (''distinct'')
 
            </ul>
        </div>
    </div>
 
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Stimulant]]s [[File:Arrow-up.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Analysis enhancement]]''' (''strong'')
*'''[[Appetite suppression]]''' (''strong'')
*'''[[Euphoria]]''' (''distinct'')
*'''[[Focus enhancement]]''' (''strong'')
*'''[[Stimulation]]''' (''distinct'')
*'''[[Thought acceleration]]''' (''distinct'')
*'''[[Wakefulness]]''' (''strong'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Cannabis]] [[File:Cannabis_leaf_%281%29.svg|x23px|right|link=]]</h3>
 
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety]]''' (''distinct'')
*'''[[Appetite enhancement]]''' (''subtle'')
*'''[[Conceptual thinking]]''' (''subtle'')
*'''[[Nausea suppression]]''' (''distinct'')
*'''[[Pain relief]]''' (''distinct'')
*'''[[Paranoia]]''' (''distinct'')
*'''[[Physical euphoria]]''' (''distinct'')
*'''[[Sedation]]''' or '''[[stimulation]]''' (''distinct'') (depending on the strain)
*'''[[Thought connectivity]]''' (''distinct'')
*'''[[Thought deceleration]]''' (''distinct'')
                </li>
            </ul>
        </div>
    </div>
 
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Benzodiazepine]]s [[File:McCormick Pills.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Amnesia]]''' (''subtle'')
*'''[[Anxiety suppression]]''' (''distinct'')
*'''[[Disinhibition]]''' (''subtle'')
*'''[[Muscle relaxation]]''' (''subtle'')
*'''[[Sedation]]''' (''subtle'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Opioid]]s [[File:Syringe-icon.png|x20px|right|link=]]</h3>
 
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Constipation]]''' (''subtle'')
*'''[[Itchiness]]''' (''distinct'')
*'''[[Pain relief]]''' (''distinct'')
*'''[[Physical euphoria|Physical]]''' and '''[[cognitive euphoria]]''' (''distinct'')
                </li>
            </ul>
        </div>
    </div>
</div>
 
==='''Strong'''===
A strong dose renders its subject as mostly incapable of functioning or interacting normally, or thinking in a sober manner. The effects of the drug are clear, but at this level they are no longer ignorable and the user is engaged entirely in the experience.
 
The panels below demonstrate which effects generally occur at a [[Dosage#Strong|strong]] dose for various classes of psychoactive substances.
<div class='flex-panel'>
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Psychedelic]]s [[File:eye.svg|x20px|right|link=]]</h3>
            <ul class="featured-table">
                <li class="featured list-item">
<h4 class="media-heading">[[Visual effects]]</h4>
*'''[[Autonomous entities]]''' (''strong'')
*'''[[Geometry]]''' (''strong'') (level [[Geometry#5._3-Dimensional_Geometry|5]] - [[Geometry#6._Partially_Overriding_Visual_Perception|6]])
*'''[[Hallucinatory states]]''' (''strong'')
*'''[[Pattern recognition enhancement]]''' (''strong'')
*'''[[Pattern recognition enhancement]]''' (''strong'')
*'''[[Symmetrical texture repetition]]''' (''strong'')
*'''[[Tracers]]''' (''strong'')
*'''[[Transformations]]''' (''strong'')
*'''[[Visual distortions]]''' (''strong'')
*'''[[Visual enhancements]]''' (''strong'')
                <li class="featured list-item">
                    <h4 class="media-heading">Other</h4>
*'''[[Analysis enhancement]]''' (''strong'')
*'''[[Auditory enhancement]]s''' (''strong'')
*'''[[Conceptual thinking]]''' (''strong'')
*'''[[Creativity enhancement]]''' (''strong'')
*'''[[Delusions]]''' (''intense'')
*'''[[Emotion enhancement]]''' (''strong'')
*'''[[Memory suppression|Complete long-term memory suppression]]''' (''strong'')
**'''[[Ego death]]''' (''strong'')
*'''[[Novelty enhancement]]''' (''strong'')
*'''[[Personal bias suppression]]''' (''strong'')
*'''[[Spiritual states]]''' (''strong'')
*'''[[Wakefulness]]''' (''strong'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Dissociative]]s [[File:Chain-broken.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''strong'')
*'''[[Cognitive euphoria]]''' (''strong'')
*'''[[Delusions]]''' (''distinct'')
*'''[[Depersonalization]]''' (''distinct'')
*'''[[Derealization]]''' (''distinct'')
*'''[[Double vision]]''' (''strong'')
*'''[[Immersion enhancement]]''' (''distinct'')
*'''[[Pain relief]]''' (''strong'')
                <li class="featured list-item">
<h4 class="media-heading">[[Visual disconnection#Holes, spaces and voids|
K-hole]]</h4>
*'''[[Consciousness disconnection]]''' (''strong'')
*'''[[Ego death]]''' (strong)
*'''[[Tactile disconnection]]''' (''strong'')
*'''[[Visual disconnection]]''' (''strong'')
**'''[[Holes, spaces and voids]]''' (''strong'')
***'''[[Structures]]''' (''strong'')
            </ul>
        </div>
    </div>
 
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Stimulant]]s [[File:Arrow-up.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Analysis enhancement]]''' (''strong'')
*'''[[Anxiety]]''' (''subtle'')
*'''[[Appetite suppression]]''' (''intense'')
*'''[[Euphoria]]''' (''strong'')
*'''[[Focus enhancement]]''' (''strong'')
*'''[[Stimulation]]''' (''strong'')
*'''[[Thought acceleration]]''' (''strong'')
*'''[[Wakefulness]]''' (''strong'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Cannabis]] [[File:Cannabis_leaf_%281%29.svg|x23px|right|link=]]</h3>
 
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety]]''' (''distinct'')
*'''[[Appetite enhancement]]''' (''strong'')
*'''[[Conceptual thinking]]''' (''subtle'')
*'''[[Nausea suppression]]''' (''strong'')
*'''[[Pain relief]]''' (''distinct'' or ''strong'') (depending on the type of pain)
*'''[[Paranoia]]''' (''distinct'')
*'''[[Physical euphoria]]''' (''distinct'')
*'''[[Sedation]]''' or '''[[stimulation]]''' (''distinct'') (depending on the strain)
*'''[[Thought connectivity]]''' (''strong'')
*'''[[Thought deceleration]]''' (''strong'')
                </li>
            </ul>
        </div>
    </div>
 
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Benzodiazepine]]s [[File:McCormick Pills.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''strong'')
*'''[[Disinhibition]]''' (''strong'')
*'''[[Muscle relaxation]]''' (''strong'')
*'''[[Sedation]]''' (''strong'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Opioid]]s [[File:Syringe-icon.png|x20px|right|link=]]</h3>
 
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Constipation]]''' (''distinct'')
*'''[[Itchiness]]''' (''strong'')
*'''[[Pain relief]]''' (''strong'')
*'''[[Physical euphoria|Physical]]''' and '''[[cognitive euphoria]]''' (''strong'')
*'''[[Respiratory depression]]''' (''strong'')
                </li>
            </ul>
        </div>
    </div>
</div>
 
==='''Heavy'''===
At heavy doses, the user has reached the upper limit of what this compound is capable of producing in terms of perceivable psychoactive effects. Depending on the substance consumed, the user may be rendered incapable of functioning on any basic level, experience extremely uncomfortable side effects, or hit a ceiling dose with diminishing returns.
 
The panels below demonstrate which effects generally occur at a [[Dosage#Heavy|heavy]] dose for various classes of psychoactive substances.
<div class='flex-panel'>
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Psychedelic]]s [[File:eye.svg|x20px|right|link=]]</h3>
            <ul class="featured-table">
                <li class="featured list-item">
<h4 class="media-heading">Visual</h4>
*'''[[Autonomous entities]]''' (''intense'')
*'''[[Geometry]]''' (''intense'') (level [[Geometry#6._Partially_Overriding_Visual_Perception|6]] - [[Geometry#8A_-_Exposure_to_semantic_concept_network|8A]]/[[Geometry#8B_-_Exposure_to_inner_mechanics_of_consciousness|8B]])
*'''[[Hallucinatory states]]''' (''intense'')
*'''[[Pattern recognition enhancement]]''' (''strong'')
*'''[[Symmetrical texture repetition]]''' (''strong'')
*'''[[Tracers]]''' (''strong'')
*'''[[Transformations]]''' (''intense'')
*'''[[Visual distortions]]''' (''intense'')
                <li class="featured list-item">
<h4 class="media-heading">Other</h4>
*'''[[Analysis enhancement]]''' (''strong'')
*'''[[Auditory enhancement]]s''' (''strong'')
*'''[[Conceptual thinking]]''' (''strong'')
*'''[[Delusions]]''' (''intense'')
*'''[[Emotion enhancement]]''' (''strong'')
*'''[[Memory suppression|Partial long-term memory suppression]]''' (''intense'')
**'''[[Ego death]]''' (''intense'')
*'''[[Novelty enhancement]]''' (''strong'')
*'''[[Personal bias suppression]]''' (''strong'')
*'''[[Spiritual states]]''' (''strong'')
*'''[[Wakefulness]]''' (''strong'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Dissociative]]s [[File:Chain-broken.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''strong'')
*'''[[Cognitive euphoria]]''' (''strong'')
*'''[[Delusions]]''' (''strong'')
*'''[[Depersonalization]]''' (''distinct'')
*'''[[Derealization]]''' (''distinct'')
*'''[[Immersion enhancement]]''' (''intense'')
*'''[[Pain relief]]''' (''intense'')
                <li class="featured list-item">
<h4 class="media-heading">[[Visual disconnection#Holes, spaces and voids|K-hole]]</h4>
*'''[[Consciousness disconnection]]''' (''strong'')
*'''[[Ego death]]''' (''strong'')
*'''[[Tactile disconnection]]''' (''strong'')
*'''[[Visual disconnection]]''' (''strong'')
**'''[[Holes, spaces and voids]]''' (''intense'')
***'''[[Structures]]''' (''intense'')
            </ul>
        </div>
    </div>
 
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Stimulant]]s [[File:Arrow-up.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Analysis enhancement]]''' (''strong'')
*'''[[Anxiety]]''' (''intense'')
*'''[[Appetite suppression]]''' (''intense'')
*'''[[Euphoria]]''' (''strong'')
*'''[[Focus enhancement]]''' (''strong'')
*'''[[Increased heart rate]]''' (''intense'')
*'''[[Stimulation]]''' (''intense'')
*'''[[Thought acceleration]]''' (''strong'')
*'''[[Wakefulness]]''' (''intense'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Cannabinoid]]s [[File:Cannabis_leaf_%281%29.svg|x23px|right|link=]]</h3>
 
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety#Panic_attacks|Panic attack]]''' (''strong'') (although rare)
*'''[[Anxiety]]''' (''intense'')
*'''[[Appetite enhancement]]''' (''strong'')
*'''[[Conceptual thinking]]''' (''strong'')
*'''[[Delusions]]''' (''subtle'')
*'''[[Nausea suppression]]''' (''distinct'')
*'''[[Pain relief]]''' (''distinct'')
*'''[[Paranoia]]''' (''intense'')
*'''[[Physical euphoria]]''' (''intense'')
*'''[[Sedation]]''' or '''[[stimulation]]''' (''distinct'') (depending on the strain)
*'''[[Thought connectivity]]''' (''distinct'')
*'''[[Thought deceleration]]''' (''distinct'')
                </li>
            </ul>
        </div>
    </div>
 
    <div class='flex-column'>
        <div class="panel radius">
            <h3 class="panel-header">[[Benzodiazepine]]s [[File:McCormick Pills.svg|x20px|right|link=]]</h3>
           
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Anxiety suppression]]''' (''intense'')
*'''[[Disinhibition]]''' (''intense'')
*'''[[Muscle relaxation]]''' (''intense'')
*'''[[Sedation]]''' (''intense'')
            </ul>
        </div>
 
        <div class="panel radius">
            <h3 class="panel-header">[[Opioid]]s [[File:Syringe-icon.png|x20px|right|link=]]</h3>
 
            <ul class="featured-table">
                <li class="featured list-item">
*'''[[Constipation]]''' (''strong'')
*'''[[Itchiness]]''' (''strong'')
*'''[[Nausea]]''' (''strong'')
*'''[[Pain relief]]''' (''intense'')
*'''[[Physical euphoria|Physical]]''' and '''[[cognitive euphoria]]''' (''intense'')
                </li>
            </ul>
        </div>
    </div>
</div>
 
==='''Overdose'''===
An overdose is a quantity greater than recommended, intended or generally practiced, with the possibility of the dose resulting in death or serious injury. Immediate professional medical advice should always be sought when a user has taken a dose greater than or equal to this, although tolerance may allow experienced users' bodies to survive such doses unharmed. It should be noted that doses below this level may also be harmful in some cases.