Substituted tropanes: Difference between revisions

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Tropane alkaloids are mostly [[Acetylcholine#The cholinergic system|anti-cholinergics]] (antagonistic action on acetylcholine [[receptors]]) or [[stimulant]]s (prevention of [[dopamine]] reuptake).

==~~Examples~~==

==List of substituted tropanes==

~~Substituted tropanes are seen throughout organic chemistry and include psychoactive and anaesthetic compounds.~~

{| class="wikitable"

|-

'''~~Anticholinergic drugs~~:'''

! scope="col" | '''Compound'''

*[[Atropine]]

! scope="col" style="width: 50px;" | '''R2'''

*[[Benzatropine]]

! scope="col" style="width: 50px;" | '''R3'''

*[[Hyoscyamine]]

! scope="col" style="width: 50px;" | '''R6'''

*[[Scopolamine]]

! scope="col" style="width: 50px;" | '''R7'''

! scope="col" | '''Structure'''

'''~~Stimulant drugs:~~'''

|-

*[[~~2-HO-Cocaine~~]]

| [[Atropine]] || H || OCOCH(CH2OH)C6H5 || H || H || [[File:Atropine.svg|170px]]

*[[~~4-Fl-Cocaine~~]]

|-

*[[~~Cocaine~~]]

| [[Hyoscyamine]] || H || OCOCH(CH2OH)C6H5 || H || H || [[File:Hyoscyamine.svg|170px]]

*[[~~REC~~]]

|-

*[[~~RTI-111~~]]

| [[Scopolamine]] || H || OCOCH(CH2OH)C6H5 || O- || - || [[File:Scopolamine.svg|170px]]

*[[~~RTI-126~~]]

|-

*[[~~RTI-31~~]]

| [[Cocaine]] || CO2CH3 || OCOC6H5 || H || H || [[File:Cocaine.svg|170px]]

*[[~~Tesofensine~~]]

|-

| [[Troparil]] || CO2CH3 || C6H5 || H || H || [[File:Troparil.svg|170px]]

~~==See also==~~

|-

*[[~~Responsible use~~]]

| [[RTI-111]] || CO2CH3 || C6H3Cl2 || H || H || [[File:RTI-111.svg|170px]]

*[[~~Deliriants~~]]

|-

*[[~~Anti~~-~~histamines~~]]

|}

*[[~~Stimulants~~]]

*[[Datura]]

==External links==

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[[Category:Chemical class]]

[[Category:Tropane|*]]

@@ Line 10: / Line 10: @@
 Tropane alkaloids are mostly [[Acetylcholine#The cholinergic system|anti-cholinergics]] (antagonistic action on acetylcholine [[receptors]]) or [[stimulant]]s (prevention of [[dopamine]] reuptake).
-==Examples==
+==List of substituted tropanes==
-Substituted tropanes are seen throughout organic chemistry and include psychoactive and anaesthetic compounds.
+{| class="wikitable"
+|-
-'''Anticholinergic drugs:'''
+! scope="col" | '''Compound'''
-*[[Atropine]]
+! scope="col" style="width: 50px;" | '''R<sub>2</sub>'''
-*[[Benzatropine]]
+! scope="col" style="width: 50px;" | '''R<sub>3</sub>'''
-*[[Hyoscyamine]]
+! scope="col" style="width: 50px;" | '''R<sub>6</sub>'''
-*[[Scopolamine]]
+! scope="col" style="width: 50px;" | '''R<sub>7</sub>'''
+! scope="col" | '''Structure'''
-'''Stimulant drugs:'''
+|-
-*[[2-HO-Cocaine]]
+| [[Atropine]] || H ||  OCOCH(CH<sub>2</sub>OH)C<sub>6</sub>H<sub>5</sub> || H || H || [[File:Atropine.svg|170px]]
-*[[4-Fl-Cocaine]]
+|-
-*[[Cocaine]]
+| [[Hyoscyamine]] || H ||  OCOCH(CH<sub>2</sub>OH)C<sub>6</sub>H<sub>5</sub> || H || H || [[File:Hyoscyamine.svg|170px]]
-*[[REC]]
+|-
-*[[RTI-111]]
+| [[Scopolamine]] || H ||  OCOCH(CH<sub>2</sub>OH)C<sub>6</sub>H<sub>5</sub> || O- || - || [[File:Scopolamine.svg|170px]]
-*[[RTI-126]]
+|-
-*[[RTI-31]]
+| [[Cocaine]] || CO</sub>2</sub>CH</sub>3</sub> ||  OCOC<sub>6</sub>H<sub>5</sub> || H || H || [[File:Cocaine.svg|170px]]
-*[[Tesofensine]]
+|-
+| [[Troparil]] || CO</sub>2</sub>CH</sub>3</sub> ||  C<sub>6</sub>H<sub>5</sub> || H || H || [[File:Troparil.svg|170px]]
-==See also==
+|-
-*[[Responsible use]]
+| [[RTI-111]] || CO</sub>2</sub>CH</sub>3</sub> ||  C<sub>6</sub>H<sub>3</sub>Cl<sub>2</sub> || H || H || [[File:RTI-111.svg|170px]]
-*[[Deliriants]]
+|-
-*[[Anti-histamines]]
+|}
-*[[Stimulants]]
-*[[Datura]]
 ==External links==
@@ Line 44: / Line 42: @@
 [[Category:Chemical class]]
 [[Category:Tropane|*]]
+{{#set:Featured=true}}