Talk:Cabergoline: Difference between revisions

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~~[[File:~~Cabergoline~~.svg|300px|thumbnail|The structure of cabergoline]]~~

'''Cabergoline''' is a chemical of the [[lysergamide]] and ergopeptine classes. It is a close derivative of [[LSD]], or more specifically, [[AL-LAD]], but instead shares many effects with related, non-psychedelic medicinal compounds such as [[ergotamine]], ergonovine or [[lisuride]]. It is occasionally prescribed to treat symptoms of high prolactin levels and managing Parkinson's disease.

'''Cabergoline''' is a chemical of the [[lysergamide]] and ergopeptine classes. It is a close derivative of [[LSD]], more specifically, [[AL-LAD]], but instead shares many effects with related, non-psychedelic medicinal compounds such as [[ergotamine]], ergonovine or [[lisuride]]. It is occasionally prescribed to treat symptoms of high prolactin levels and managing Parkinson's disease.

Cabergoline is not predominantly psychedelic, it mainly exerts its effects at the [[dopamine]] D<sub>2</sub> receptor as an agonist but has comparatively little effect on the [[serotonin]] 5-HT<sub>2A</sub> receptor where it acts as a partial agonist.

Cabergoline has little recreational value other than its unique property of reducing or eliminating the male refractory period, ~~thereby~~ allowing men to experience multiple ejaculatory orgasms in rapid succession.<ref>Krüger TH, Haake P, Haverkamp J, ~~et al~~. (~~December 2003~~). "Effects of acute prolactin manipulation on sexual drive and function in males~~". Journal of Endocrinology.~~ 179 (3~~): 357–65. CiteSeerX 10.1.1.484.4005.~~ doi:10.1677/joe.0.1790357~~. PMID 14656205.~~</ref><ref>Hollander, ~~Adam~~ B.; Pastuszak, ~~Alexander~~ W.; Lipshultz, ~~Larry~~ I. ~~(2016~~)~~. "~~Cabergoline in the Treatment of Male Orgasmic ~~Disorder—A~~ Retrospective Pilot Analysis~~". Journal of Sexual Medicine.~~ 4 ~~(4): e28–e33.~~ doi:10.1016/j.esxm.2015.09.001~~. PMC 4822480. PMID 26944776.~~</ref>

Cabergoline has little recreational value other than its unique property of reducing or eliminating the male refractory period, allowing men to experience multiple ejaculatory orgasms in rapid succession.<ref>{{cite journal | vauthors=((Krüger, T. H. C.)), ((Haake, P.)), ((Haverkamp, J.)), ((Krämer, M.)), ((Exton, M. S.)), ((Saller, B.)), ((Leygraf, N.)), ((Hartmann, U.)), ((Schedlowski, M.)) | journal=The Journal of Endocrinology | title=Effects of acute prolactin manipulation on sexual drive and function in males | volume=179 | issue=3 | pages=357–365 | date= December 2003 | issn=0022-0795 | doi=10.1677/joe.0.1790357}}</ref><ref>{{cite journal | vauthors=((Hollander, A. B.)), ((Pastuszak, A. W.)), ((Hsieh, T.-C.)), ((Johnson, W. G.)), ((Scovell, J. M.)), ((Mai, C. K.)), ((Lipshultz, L. I.)) | journal=Sexual Medicine | title=Cabergoline in the Treatment of Male Orgasmic Disorder-A Retrospective Pilot Analysis | volume=4 | issue=1 | pages=e28-33 | date= March 2016 | issn=2050-1161 | doi=10.1016/j.esxm.2015.09.001}}</ref>

==See also==

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-[[File:Cabergoline.svg|300px|thumbnail|The structure of cabergoline]]
+{{SummarySheet}}
-'''Cabergoline''' is a chemical of the [[lysergamide]] and ergopeptine classes. It is a close derivative of [[LSD]], or more specifically, [[AL-LAD]], but instead shares many effects with related, non-psychedelic medicinal compounds such as [[ergotamine]], ergonovine or [[lisuride]]. It is occasionally prescribed to treat symptoms of high prolactin levels and managing Parkinson's disease.
+{{SubstanceBox/Cabergoline}}
+'''Cabergoline''' is a chemical of the [[lysergamide]] and ergopeptine classes. It is a close derivative of [[LSD]], more specifically, [[AL-LAD]], but instead shares many effects with related, non-psychedelic medicinal compounds such as [[ergotamine]], ergonovine or [[lisuride]]. It is occasionally prescribed to treat symptoms of high prolactin levels and managing Parkinson's disease.
 Cabergoline is not predominantly psychedelic, it mainly exerts its effects at the [[dopamine]] D<sub>2</sub> receptor as an agonist but has comparatively little effect on the [[serotonin]] 5-HT<sub>2A</sub> receptor where it acts as a partial agonist.
-Cabergoline has little recreational value other than its unique property of reducing or eliminating the male refractory period, thereby allowing men to experience multiple ejaculatory orgasms in rapid succession.<ref>Krüger TH, Haake P, Haverkamp J, et al. (December 2003). "Effects of acute prolactin manipulation on sexual drive and function in males". Journal of Endocrinology. 179 (3): 357–65. CiteSeerX 10.1.1.484.4005. doi:10.1677/joe.0.1790357. PMID 14656205.</ref><ref>Hollander, Adam B.; Pastuszak, Alexander W.; Lipshultz, Larry I. (2016). "Cabergoline in the Treatment of Male Orgasmic Disorder—A Retrospective Pilot Analysis". Journal of Sexual Medicine. 4 (4): e28–e33. doi:10.1016/j.esxm.2015.09.001. PMC 4822480. PMID 26944776.</ref>
+Cabergoline has little recreational value other than its unique property of reducing or eliminating the male refractory period, allowing men to experience multiple ejaculatory orgasms in rapid succession.<ref>{{cite journal | vauthors=((Krüger, T. H. C.)), ((Haake, P.)), ((Haverkamp, J.)), ((Krämer, M.)), ((Exton, M. S.)), ((Saller, B.)), ((Leygraf, N.)), ((Hartmann, U.)), ((Schedlowski, M.)) | journal=The Journal of Endocrinology | title=Effects of acute prolactin manipulation on sexual drive and function in males | volume=179 | issue=3 | pages=357–365 | date= December 2003 | issn=0022-0795 | doi=10.1677/joe.0.1790357}}</ref><ref>{{cite journal | vauthors=((Hollander, A. B.)), ((Pastuszak, A. W.)), ((Hsieh, T.-C.)), ((Johnson, W. G.)), ((Scovell, J. M.)), ((Mai, C. K.)), ((Lipshultz, L. I.)) | journal=Sexual Medicine | title=Cabergoline in the Treatment of Male Orgasmic Disorder-A Retrospective Pilot Analysis | volume=4 | issue=1 | pages=e28-33 | date= March 2016 | issn=2050-1161 | doi=10.1016/j.esxm.2015.09.001}}</ref>
 ==See also==