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Substituted piperazines: Difference between revisions
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[[File:Piperazine. | {{stub}} | ||
'''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects. | [[File:Piperazine.svg|thumb|right|100px||The structure of the piperazine molecule]] | ||
'''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects. They can be divided into two classes, the benzylpiperazines such as [[BZP]] itself, and its methylenedioxy analogue [[MDBZP]], and the phenylpiperazines [[mCPP]], [[TFMPP]], and [[MeOPP]]. Some deaths have rarely occurred when consuming BZP, it can increase chances of having seizures. | |||
==Chemistry== | ==Chemistry== | ||
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Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring. | Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring. | ||
=== | <div class="flex-panel"> | ||
*[[BZP]] | <div class="flex-column"> | ||
*[[mCPP]] | <div class="panel radius"> | ||
*[[TFMPP]] | <h3 class="panel-header">Recreational Piperazines</h3> | ||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[2C-B-BZP]] | |||
*[[3C-PEP]] | |||
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'') | |||
*[[BZP]] (''Benzylpiperazine'') | |||
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'') | |||
*[[DBZP]] (''1,4-Dibenzylpiperazine'') | |||
*[[MBZP]] (''4-Methyl-1-benzylpiperazine'') | |||
*[[MDBZP]] (''Methylenedioxybenzylpiperazine'') | |||
*[[mCPP]] (''3-Chlorophenylpiperazine'') | |||
*[[MDBZP]] (''3,4-Methylenedioxy-1-benzylpiperazine'') | |||
*[[MeOP]] (''Methoxypiperamide'') | |||
*[[MeOPP]] (''para-methoxyphenylpiperazine'') | |||
*[[MT-45]] (''1-cyclohexyl-4-(1,2-diphenylethyl)piperazine'') | |||
*[[mTFMPP]] | |||
*[[oCPP]] (''2-Chlorophenylpiperazine'') | |||
*[[oMPP]] (''2-Methylphenylpiperazine'') | |||
*[[oMeOPP]] (''2-Methoxyphenylpiperazine'') | |||
*[[oTFMPP]] | |||
*[[pCPP]] (''4-Chlorophenylpiperazine'') | |||
*[[pFPP]] (''4-Fluorophenylpiperazine'') | |||
*[[pTFMPP]] | |||
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'') | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Benzylpiperazines</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[2C-B-BZP]] | |||
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'') | |||
*[[Befuraline]] | |||
*[[Bifeprunox]] | |||
*[[Buclizine]] | |||
*[[BZP]] (''Benzylpiperazine'') | |||
*[[Chlorbenzoxamine]] | |||
*[[DBZP]] | |||
*[[DF-MDBP]] (''Difluoromethylenedioxybenzylpiperazine'') | |||
*[[Fipexide]] | |||
*[[Imatinib]] | |||
*[[MBZP]] | |||
*[[MDBZP]] | |||
*[[Meclozine]] | |||
*[[MeOP]] (''Methoxypiperamide'') | |||
*[[Piberaline]] | |||
*[[Piribedil]] | |||
*[[RN-1747]] | |||
*[[Sunifiram]] | |||
*[[Trimetazidine]] | |||
*[[TFMCPP]] (''3-Trifluoromethyl-4-chlorophenylpiperazine'') | |||
*[[Vesnarinone]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Phenylpiperazines</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[2C-B-PP]] (''2,5-dimethoxy-4-bromophenylpiperazine'') | |||
*[[3,4-CFP]] (''3-Chloro-4-fluorophenylpiperazine'') | |||
*[[3C-PEP]] | |||
*[[Acaprazine]] | |||
*[[Aripiprazole]] (''Abilify'') | |||
*[[Bifeprunox]] | |||
*[[Brexpiprazole]] | |||
*[[Cariprazine]] | |||
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'') | |||
*[[Elopiprazole]] | |||
*[[Enciprazine]] | |||
*[[Enpiprazole]] | |||
*[[Ensaculin]] | |||
*[[Etoperidone]] | |||
*[[Flesinoxan]] | |||
*[[Lorpiprazole]] | |||
*[[Mepiprazole]] | |||
*[[mCPP]] (''3-Chlorophenylpiperazine'') | |||
*[[mMeOPP]] (''3-Methoxyphenylpiperazine'') | |||
*[[Naluzotan]] | |||
*[[Naphthylpiperazine]] | |||
*[[Nefazodone]] | |||
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'') | |||
*[[Tolpiprazole]] | |||
*[[Trazodone]] | |||
*[[Vilazodone]] | |||
*[[Vortioxetine]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Pyrimidinylpiperazine</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[Buspirone]] | |||
*[[Dasatinib]] | |||
*[[Eptapirone]] | |||
*[[Gepirone]] | |||
*[[Ipsapirone]] | |||
*[[Piribedil]] | |||
*[[Quipazine]] | |||
*[[Revospirone]] | |||
*[[Tandospirone]] | |||
*[[Tirilazad]] | |||
*[[Umespirone]] | |||
*[[Zalospirone]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Pyridinylpiperazine</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[Azaperone]] | |||
*[[Atevirdine]] | |||
*[[Delavirdine]] | |||
*[[Mirtazapine]] | |||
*[[ORG-12962]] | |||
*[[ORG-37684]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Other</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[AD-1211]] | |||
*[[AP-238]] | |||
*[[Azaprocin]] | |||
*[[Buclizine]] | |||
*[[Bucinnazine]] (''AP-237'') | |||
*[[Cetirizine]] (''Zyrtec'') | |||
*[[Chlorcyclizine]] | |||
*[[Cinnarizine]] | |||
*[[Cyclizine]] | |||
*[[Diphenpipenol]] | |||
*[[Etodroxizine]] | |||
*[[Flunarizine]] | |||
*[[Homochlorcyclizine]] | |||
*[[Hydroxyzine]] | |||
*[[Meclizine]] | |||
*[[MT-45]] (''IC-6'') | |||
*[[NSI-189]] | |||
*[[Oxatomide]] | |||
*[[Perospirone]] | |||
*[[Pipoxizine]] | |||
*[[Tiospirone]] | |||
*[[Unifiram]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
</div> | |||
==Pharmacology== | ==Pharmacology== | ||
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*[[Responsible use]] | *[[Responsible use]] | ||
*[[Dopamine]] | *[[Dopamine]] | ||
*[[ | *[[Substituted piperidine]] | ||
==External links== | |||
*[Piperazine (Wikipedia)https://en.wikipedia.org/wiki/Piperazine] | |||
*[https://en.wikipedia.org/wiki/Substituted_piperazine Substituted piperazine (Wikipedia)] | |||
*[https://erowid.org/chemicals/piperazines/piperazines.shtml Piperazines (Erowid Vault)] | |||
==References== | ==References== | ||
{{references}} | {{references}} | ||
[[Category:Chemical class]] | |||
[[Category:Piperazine|*]] | |||