Substituted benzofurans: Difference between revisions

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[[File:~~Benzofuran~~.~~png~~]]

'''Benzofurans''' are chemical compounds, which contain a benzofuran ring. ~~They~~ are commonly [[stimulants]] or [[entactogens]].

[[File:Substituted_benzofuran.svg|thumb|right|299px||Generic structure of a benzofuran class molecule]]

'''Benzofurans''' are chemical compounds which contain a benzofuran ring in their structure. Most of the benzofurans are [[research chemicals]], most commonly [[stimulants]] and [[entactogens]], and are fairly new. Benzofuran compounds are often analogues of [[MDxx]] and [[tryptamine]] compounds where a benzofuran ring has replaced the benzodioxole ring structure or indole ring respectively.

===~~Examples~~===

== List of benzofuran compounds ==

* [[5-APB]]

{| class="wikitable"

* [[5-APDB]]

|-

* [[5-MeO-~~DiBF~~]]

! scope="col" | '''Compound'''

* [[6-APB]]

! scope="col" style="width: 50px;" | '''R2'''

* [[6-APDB]]

! scope="col" style="width: 50px;" | '''R3'''

! scope="col" style="width: 50px;" | '''R4'''

! scope="col" style="width: 50px;" | '''R5'''

! scope="col" style="width: 50px;" | '''R6'''

! scope="col" style="width: 50px;" | '''R7'''

! scope="col" | '''Structure'''

|-

| Benzofuran || H || H || H || H || H || H || [[File:Benzofuran.svg|130px]]

|-

| 2-APB || CH2CH(NH2)CH3 || H || H || H || H || H || [[File:2-APB.svg|170px]]

|-

| 2-MAPB || CH2CH(NHCH3)CH3 || H || H || H || H || H || [[File:2-MAPB.svg|170px]]

|-

| 2-EAPB || CH2CH(NHCH2CH3)CH3 || H || H || H || H || H || [[File:2-EAPB.svg|170px]]

|-

| 3-APB || H || CH2CH(NH2)CH3 || H || H || H || H || [[File:3-APB.svg|170px]]

|-

| Mebfap || H || CH2CH(NH2)CH3 || H || OCH3 || H || H || [[File:Mebfap.svg|170px]]

|-

| 5-MeO-BFE || H || CH2CH2N(CH3)2 || H || OCH3 || H || H || [[File:5-MeO-BFE.svg|170px]]

|-

| [[5-MeO-DiBF]] || H || CH2CH2N(CH(CH3)2)2 || H || OCH3 || H || H || [[File:5-MeO-DiBF.svg|170px]]

|-

| 4-APB || H || H || CH2CH(NH2)CH3 || H || H || H || [[File:4-APB.svg|170px]]

|-

| DOB-5-hemifly || H2 || H2 || CH2CH(NH2)CH3 || OCH3 || H || Br || [[File:DOB-5-hemifly.svg|170px]]

|-

| [[5-APB]] || H || H || H || CH2CH(NH2)CH3 || H || H || [[File:5-APB.svg|170px]]

|-

| 5-APDB || H2 || H2 || H || CH2CH(NH2)CH3 || H || H || [[File:5-APDB.svg|170px]]

|-

| [[5-MAPB]] || H || H || H || CH2CH(NHCH3)CH3 || H || H || [[File:5-MAPB.svg|170px]]

|-

| 5-MAPDB || H2 || H2 || H || CH2CH(NHCH3)CH3 || H || H || [[File:5-MAPDB.svg|170px]]

|-

| βk-5-MAPB || H || H || H || COCH(NHCH3)CH3 || H || H || [[File:βk-5-MAPB.svg|170px]]

|-

| 5-EAPB || H || H || H || CH2CH(NHCH2CH3)CH3 || H || H || [[File:5-EAPB.svg|170px]]

|-

| 5-EAPDB || H2 || H2 || H || CH2CH(NHCH2CH3)CH3 || H || H || [[File:5-EAPDB.svg|170px]]

|-

| 5-MBPB || H || H || H || CH2CH(NHCH3)CH2CH3 || H || H || [[File:5-MBPB.svg|170px]]

|-

| 5-DBFPV || H2 || H2 || H || COCH(NC4H8)CH2CH2CH3 || H || H || [[File:5-DBFPV.svg|170px]]

|-

| 6-MeO-5-APDB || H2 || H2 || H || CH2CH(NH2)CH3 || OCH3 || H || [[File:6-MeO-5-APDB.svg|170px]]

|-

| [[6-APB]] || H || H || H || H || CH2CH(NH2)CH3 || H || [[File:6-APB.svg|170px]]

|-

| [[6-APDB]] || H2 || H2 || H || H || CH2CH(NH2)CH3 || H || [[File:6-APDB.svg|170px]]

|-

| 6-MAPB || H || H || H || H || CH2CH(NHCH3)CH3 || H || [[File:6-MAPB.svg|170px]]

|-

| 6-MAPDB || H2 || H2 || H || H || CH2CH(NHCH3)CH3 || H || [[File:6-MAPDB.svg|170px]]

|-

| βk-6-MAPB || H || H || H || H || COCH(NHCH3)CH3 || H || [[File:βk-6-MAPB.svg|170px]]

|-

| 6-EAPB || H || H || H || H || CH2CH(NHCH2CH3)CH3 || H || [[File:6-EAPB.svg|170px]]

|-

| 6-EAPDB || H2 || H2 || H || H || CH2CH(NHCH2CH3)CH3 || H || [[File:6-EAPDB.svg|170px]]

|-

| 6-MBPB || H || H || H || H || CH2CH(NHCH3)CH2CH3 || H || [[File:6-MBPB.svg|170px]]

|-

| F-2 || HCH3 || H2 || H || OCH3 || CH2CH(NH2)CH3 || H || [[File:F-2.svg|170px]]

|-

| F-22 || (CH3)2 || H2 || H || OCH3 || CH2CH(NH2)CH3 || H || [[File:F-22.svg|170px]]

|-

| 7-APB || H || H || H || H || H || CH2CH(NH2)CH3 || [[File:7-APB.svg|170px]]

|-

| DOI-2-hemifly || H2 || H2 || I || OCH3 || H || CH2CH(NH2)CH3 || [[File:DOI-2-hemifly.svg|170px]]

|-

| [[Bromo-DragonFLY]] || H || H || Br || O- || CH=CH- || CH2CH(NH2)CH3 || [[File:Bromo-DragonFLY.svg|170px]]

|-

| [[2C-B-FLY]] || H2 || H2 || Br || OCH2- || CH2- || CH2CH2NH2 || [[File:2C-B-FLY.svg|170px]]

|-

| [[Tasimelteon]] || H2 || H2 || C3H4CH2NHCOCH2CH3 || H || H || H || [[File:Tasimelteon.svg|170px]]

|-

| [[Ramelteon]] || H2 || H2 || CH(CH2-)CH2CH2NHCOCH2CH3 || CH2- || H || H || [[File:Ramelteon.svg|170px]]

|-

| [[Vilazodone]] || CONH2 || H || H || C4H8N2(CH2)4C9H5N2 || H || H || [[File:Vilazodone.svg|230px]]

|-

|}

===See also===

==See also==

*[[Responsible use]]

*[[5-APB]]

*[[Stimulant]]

*[[Entactogen]]

*[[Phenethylamines]]

==External links==

* [https://en.wikipedia.org/wiki/Substituted_benzofuran Substituted benzofuran (Wikipedia)]

[[Category:Chemical class]]

[[Category:Benzofuran| ]]

@@ Line 1: / Line 1: @@
-[[File:Benzofuran.png]]
+{{stub}}
-'''Benzofurans''' are chemical compounds, which contain a benzofuran ring. They are commonly [[stimulants]] or [[entactogens]].
+[[File:Substituted_benzofuran.svg|thumb|right|299px||Generic structure of a benzofuran class molecule]]
+'''Benzofurans''' are chemical compounds which contain a benzofuran ring in their structure. Most of the benzofurans are [[research chemicals]], most commonly [[stimulants]] and [[entactogens]], and are fairly new. Benzofuran compounds are often analogues of [[MDxx]] and [[tryptamine]] compounds where a benzofuran ring has replaced the benzodioxole ring structure or indole ring respectively.
-===Examples===
+== List of benzofuran compounds ==
-* [[5-APB]]
+{| class="wikitable"
-* [[5-APDB]]
+|-
-* [[5-MeO-DiBF]]
+! scope="col" | '''Compound'''
-* [[6-APB]]
+! scope="col" style="width: 50px;" | '''R<sub>2</sub>'''
-* [[6-APDB]]
+! scope="col" style="width: 50px;" | '''R<sub>3</sub>'''
+! scope="col" style="width: 50px;" | '''R<sub>4</sub>'''
+! scope="col" style="width: 50px;" | '''R<sub>5</sub>'''
+! scope="col" style="width: 50px;" | '''R<sub>6</sub>'''
+! scope="col" style="width: 50px;" | '''R<sub>7</sub>'''
+! scope="col" | '''Structure'''
+|-
+| Benzofuran || H || H || H || H || H || H || [[File:Benzofuran.svg|130px]]
+|-
+| 2-APB || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || H || H || H || H || [[File:2-APB.svg|170px]]
+|-
+| 2-MAPB || CH<sub>2</sub>CH(NHCH<sub>3</sub>)CH<sub>3</sub> || H || H || H || H || H || [[File:2-MAPB.svg|170px]]
+|-
+| 2-EAPB || CH<sub>2</sub>CH(NHCH<sub>2</sub>CH<sub>3</sub>)CH<sub>3</sub> || H || H || H || H || H || [[File:2-EAPB.svg|170px]]
+|-
+| 3-APB || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || H || H || H || [[File:3-APB.svg|170px]]
+|-
+| Mebfap || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || OCH<sub>3</sub> || H || H || [[File:Mebfap.svg|170px]]
+|-
+| 5-MeO-BFE || H || CH<sub>2</sub>CH<sub>2</sub>N(CH<sub>3</sub>)<sub>2</sub> || H || OCH<sub>3</sub> || H || H || [[File:5-MeO-BFE.svg|170px]]
+|-
+| [[5-MeO-DiBF]] || H || CH<sub>2</sub>CH<sub>2</sub>N(CH(CH<sub>3</sub>)<sub>2</sub>)<sub>2</sub> || H || OCH<sub>3</sub> || H || H || [[File:5-MeO-DiBF.svg|170px]]
+|-
+| 4-APB || H || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || H || H || [[File:4-APB.svg|170px]]
+|-
+| DOB-5-hemifly || H<sub>2</sub> || H<sub>2</sub> || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || OCH<sub>3</sub> || H || Br || [[File:DOB-5-hemifly.svg|170px]]
+|-
+| [[5-APB]] || H || H || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || H || [[File:5-APB.svg|170px]]
+|-
+| 5-APDB || H<sub>2</sub> || H<sub>2</sub> || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || H || [[File:5-APDB.svg|170px]]
+|-
+| [[5-MAPB]] || H || H || H || CH<sub>2</sub>CH(NHCH<sub>3</sub>)CH<sub>3</sub> || H || H || [[File:5-MAPB.svg|170px]]
+|-
+| 5-MAPDB || H<sub>2</sub> || H<sub>2</sub> || H || CH<sub>2</sub>CH(NHCH<sub>3</sub>)CH<sub>3</sub> || H || H || [[File:5-MAPDB.svg|170px]]
+|-
+| βk-5-MAPB || H || H || H || COCH(NHCH<sub>3</sub>)CH<sub>3</sub> || H || H || [[File:βk-5-MAPB.svg|170px]]
+|-
+| 5-EAPB || H || H || H || CH<sub>2</sub>CH(NHCH<sub>2</sub>CH<sub>3</sub>)CH<sub>3</sub> || H || H || [[File:5-EAPB.svg|170px]]
+|-
+| 5-EAPDB || H<sub>2</sub> || H<sub>2</sub> || H || CH<sub>2</sub>CH(NHCH<sub>2</sub>CH<sub>3</sub>)CH<sub>3</sub> || H || H || [[File:5-EAPDB.svg|170px]]
+|-
+| 5-MBPB || H || H || H || CH<sub>2</sub>CH(NHCH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub> || H || H || [[File:5-MBPB.svg|170px]]
+|-
+| 5-DBFPV || H<sub>2</sub> || H<sub>2</sub> || H || COCH(NC<sub>4</sub>H<sub>8</sub>)CH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub> || H || H || [[File:5-DBFPV.svg|170px]]
+|-
+| 6-MeO-5-APDB || H<sub>2</sub> || H<sub>2</sub> || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || OCH<sub>3</sub> || H || [[File:6-MeO-5-APDB.svg|170px]]
+|-
+| [[6-APB]] || H || H || H || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || [[File:6-APB.svg|170px]]
+|-
+| [[6-APDB]] || H<sub>2</sub> || H<sub>2</sub> || H || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || [[File:6-APDB.svg|170px]]
+|-
+| 6-MAPB || H || H || H || H || CH<sub>2</sub>CH(NHCH<sub>3</sub>)CH<sub>3</sub> || H || [[File:6-MAPB.svg|170px]]
+|-
+| 6-MAPDB || H<sub>2</sub> || H<sub>2</sub> || H || H || CH<sub>2</sub>CH(NHCH<sub>3</sub>)CH<sub>3</sub> || H || [[File:6-MAPDB.svg|170px]]
+|-
+| βk-6-MAPB || H || H || H || H || COCH(NHCH<sub>3</sub>)CH<sub>3</sub> || H || [[File:βk-6-MAPB.svg|170px]]
+|-
+| 6-EAPB || H || H || H || H || CH<sub>2</sub>CH(NHCH<sub>2</sub>CH<sub>3</sub>)CH<sub>3</sub> || H || [[File:6-EAPB.svg|170px]]
+|-
+| 6-EAPDB || H<sub>2</sub> || H<sub>2</sub> || H || H || CH<sub>2</sub>CH(NHCH<sub>2</sub>CH<sub>3</sub>)CH<sub>3</sub> || H || [[File:6-EAPDB.svg|170px]]
+|-
+| 6-MBPB || H || H || H || H || CH<sub>2</sub>CH(NHCH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub> || H || [[File:6-MBPB.svg|170px]]
+|-
+| F-2 || HCH<sub>3</sub> || H<sub>2</sub> || H || OCH<sub>3</sub> || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || [[File:F-2.svg|170px]]
+|-
+| F-22 || (CH<sub>3</sub>)<sub>2</sub> || H<sub>2</sub> || H || OCH<sub>3</sub> || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || H || [[File:F-22.svg|170px]]
+|-
+| 7-APB || H || H || H || H || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || [[File:7-APB.svg|170px]]
+|-
+| DOI-2-hemifly || H<sub>2</sub> || H<sub>2</sub> || I || OCH<sub>3</sub> || H || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || [[File:DOI-2-hemifly.svg|170px]]
+|-
+| [[Bromo-DragonFLY]] || H || H || Br || O- || CH=CH- || CH<sub>2</sub>CH(NH<sub>2</sub>)CH<sub>3</sub> || [[File:Bromo-DragonFLY.svg|170px]]
+|-
+| [[2C-B-FLY]] || H<sub>2</sub> || H<sub>2</sub> || Br || OCH<sub>2</sub>- || CH<sub>2</sub>- || CH<sub>2</sub>CH<sub>2</sub>NH<sub>2</sub> || [[File:2C-B-FLY.svg|170px]]
+|-
+| [[Tasimelteon]] || H<sub>2</sub> || H<sub>2</sub> || C<sub>3</sub>H<sub>4</sub>CH<sub>2</sub>NHCOCH<sub>2</sub>CH<sub>3</sub> || H || H || H || [[File:Tasimelteon.svg|170px]]
+|-
+| [[Ramelteon]] || H<sub>2</sub> || H<sub>2</sub> || CH(CH<sub>2</sub>-)CH<sub>2</sub>CH<sub>2</sub>NHCOCH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>- || H || H || [[File:Ramelteon.svg|170px]]
+|-
+| [[Vilazodone]] || CONH<sub>2</sub> || H || H || C<sub>4</sub>H<sub>8</sub>N<sub>2</sub>(CH<sub>2</sub>)<sub>4</sub>C<sub>9</sub>H<sub>5</sub>N<sub>2</sub> || H || H || [[File:Vilazodone.svg|230px]]
+|-
+|}
-===See also===
+==See also==
+*[[Responsible use]]
+*[[5-APB]]
+*[[Stimulant]]
+*[[Entactogen]]
+*[[Phenethylamines]]
+==External links==
+* [https://en.wikipedia.org/wiki/Substituted_benzofuran Substituted benzofuran (Wikipedia)]
+[[Category:Chemical class]]
+[[Category:Benzofuran| ]]