Talk:Microdosing: Difference between revisions

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'''Microdosing''' (~~a shortened form of~~ '''psychedelic microdosing''') is the ~~novel~~ practice of using ~~subthreshold~~ doses of a psychedelic substance in ~~order~~ to ~~enhance~~ productivity, ~~treat~~ symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, and ~~to boost one's creativity, abstract thought &~~ problem-solving abilities ~~in everyday life~~, as well as ~~potentially~~ increase spiritual awareness. ~~However, it should be noted that at this time there~~ is no ~~scientific~~ evidence to support these claims.

'''Microdosing''' (also known as '''psychedelic microdosing''') is the practice of using sub-threshold doses of a psychedelic substance in an attempt to produce a therapeutic or [[nootropic]] effect. Microdosing has been claimed by some to have a wide range of benefits including enhancing productivity, treating symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, boosting creativity and problem-solving abilities, as well as increase spiritual awareness. There is currently no clinical evidence to support these claims, however a number of small scale studies have shown positive outcomes. In 2020 a study by the Beckley Foundation found that a 20 microgram dose of LSD significantly reduced pain perception when compared to a placebo, with results comparable to those observed after administration of opioids.<ref>{{Cite web|url=https://www.leafie.co.uk/psychedelics/5-things-you-need-to-know-about-microdosing/|title=5 things you need to know about microdosing|website=leafie|access-date=16 September 2021}}</ref>

While it is possible to microdose with any [[psychedelic]] substance~~, the practice has its origins with [[LSD]]~~. ~~Additionally, there is~~ a growing body of reports of ~~those who microdose with substances like~~ [[psilocybin mushrooms]], or psychedelic [[research chemicals]], particularly ~~with analogs of~~ [[LSD]] such as [[ALD-52]], [[1P-LSD]], [[AL-LAD]] and [[ETH-LAD]].

While the practice has its origins with [[LSD]], it is in theory possible to microdose with any [[psychedelic]] substance. There are a growing body of reports of microdosing [[psilocybin mushrooms]], or psychedelic [[research chemicals]], particularly [[LSD]] analogs such as [[ALD-52]], [[1P-LSD]], [[AL-LAD]] and [[ETH-LAD]].

~~Generally, a~~ microdose of LSD is considered to be between 5-20 micrograms ~~(typically 10ug, +/-2ug) which~~ can be measured ~~very~~ accurately using [[volumetric dosing]] techniques. A microdose of psilocybin mushrooms is ~~a bit~~ harder to determine due to the variations in potency between species and batches; so it is generally advised to start with no more than .25g.

Microdoses range from about one tenth of an active dose. A microdose of LSD is generally considered to be between 5-15 micrograms. This can be measured accurately using [[volumetric dosing]] techniques. A microdose of psilocybin mushrooms is harder to determine due to the variations in potency between species and batches; it is generally advised to start with no more than .25g.

==~~History and culture~~==

==Subjective effects==

~~{{historyStub}}~~

~~== Subjective effects ==~~

The panels below list the effects generally occur at a [[Dosage#Microdose|microdose]] dose for psychedelic substances according to reports by PsychonautWiki contributors.

The panels below ~~demonstrate which~~ effects generally occur at a [[Dosage#Microdose|microdose]] dose for psychedelic substances according to reports by PsychonautWiki contributors.

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*[[wikipedia:Microdosing|Microdosing (Wikipedia)]]

*[[wikipedia:Psychedelic microdosing|Psychedelic microdosing (Wikipedia)]]

==Literature==

*Horsley, R.R., Páleníček, T., Kolin, J., & Valeš, K. (2018). Psilocin and ketamine microdosing: effects of subchronic intermittent microdoses in the elevated plus-maze in male Wistar rats. Behavioural Pharmacology. https://doi.org/10.1097/FBP.0000000000000394

==References==

[[Category:Approval]]

@@ Line 1: / Line 1: @@
-'''Microdosing''' (a shortened form of '''psychedelic microdosing''') is the novel practice of using subthreshold doses of a psychedelic substance in order to enhance productivity, treat symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, and to boost one's creativity, abstract thought & problem-solving abilities in everyday life, as well as potentially increase spiritual awareness. However, it should be noted that at this time there is no scientific evidence to support these claims.
+'''Microdosing''' (also known as '''psychedelic microdosing''') is the practice of using sub-threshold doses of a psychedelic substance in an attempt to produce a therapeutic or [[nootropic]] effect. Microdosing has been claimed by some to have a wide range of benefits including enhancing productivity, treating symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, boosting creativity and problem-solving abilities, as well as increase spiritual awareness. There is currently no clinical evidence to support these claims, however a number of small scale studies have shown positive outcomes. In 2020 a study by the Beckley Foundation found that a 20 microgram dose of LSD significantly reduced pain perception when compared to a placebo, with results comparable to those observed after administration of opioids.<ref>{{Cite web|url=https://www.leafie.co.uk/psychedelics/5-things-you-need-to-know-about-microdosing/|title=5 things you need to know about microdosing|website=leafie|access-date=16 September 2021}}</ref>
-While it is possible to microdose with any [[psychedelic]] substance, the practice has its origins with [[LSD]]. Additionally, there is a growing body of reports of those who microdose with substances like [[psilocybin mushrooms]], or psychedelic [[research chemicals]], particularly with analogs of [[LSD]] such as [[ALD-52]], [[1P-LSD]], [[AL-LAD]] and [[ETH-LAD]].
+While the practice has its origins with [[LSD]], it is in theory possible to microdose with any [[psychedelic]] substance. There are a growing body of reports of microdosing [[psilocybin mushrooms]], or psychedelic [[research chemicals]], particularly [[LSD]] analogs such as [[ALD-52]], [[1P-LSD]], [[AL-LAD]] and [[ETH-LAD]].
-Generally, a microdose of LSD is considered to be between 5-20 micrograms (typically 10ug, +/-2ug) which can be measured very accurately using [[volumetric dosing]] techniques. A microdose of psilocybin mushrooms is a bit harder to determine due to the variations in potency between species and batches; so it is generally advised to start with no more than .25g.
+Microdoses range from about one tenth of an active dose. A microdose of LSD is generally considered to be between 5-15 micrograms. This can be measured accurately using [[volumetric dosing]] techniques. A microdose of psilocybin mushrooms is harder to determine due to the variations in potency between species and batches; it is generally advised to start with no more than .25g.
-==History and culture==
+==Subjective effects==
-{{historyStub}}
-== Subjective effects ==
+The panels below list the effects generally occur at a [[Dosage#Microdose|microdose]] dose for psychedelic substances according to reports by PsychonautWiki contributors.
-The panels below demonstrate which effects generally occur at a [[Dosage#Microdose|microdose]] dose for psychedelic substances according to reports by PsychonautWiki contributors.
 <div class='flex-panel'>
@@ Line 101: / Line 98: @@
 *[[wikipedia:Microdosing|Microdosing (Wikipedia)]]
 *[[wikipedia:Psychedelic microdosing|Psychedelic microdosing (Wikipedia)]]
+==Literature==
+*Horsley, R.R., Páleníček, T., Kolin, J., & Valeš, K. (2018). Psilocin and ketamine microdosing: effects of subchronic intermittent microdoses in the elevated plus-maze in male Wistar rats. Behavioural Pharmacology. https://doi.org/10.1097/FBP.0000000000000394
 ==References==
 <references />
+{{references}}
+[[Category:Approval]]