Talk:MDA/Archive 1: Difference between revisions
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*[[Current mind state enhancement|Current mind state enhancement]] | *[[Current mind state enhancement|Current mind state enhancement]] | ||
*[[Thought connectivity|Thought connectivity]] | *[[Thought connectivity|Thought connectivity]] | ||
*[[ | *[[Novelty enhancement|Novelty enhancement]] - (mild) | ||
*[[Time distortion|Time distortion]] - powerful time dilation | *[[Time distortion|Time distortion]] - powerful time dilation | ||
*[[Introspection|Introspection]] | *[[Introspection|Introspection]] | ||
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The experience of [[Auditory effects - Psychedelics#Hallucinations|auditory hallucinations]] on MDMA is extremely common, usually occurring at the end of the night, and almost always consisting of memory replays from the previous several hours. They are commonly manifested as spontaneous clips of the music that was played and garbled voices of the people that were spoken too. These can become as loud in volume as the level of noise heard at any rave or house party and can occasionally become complex enough to manifest themselves as intricate, previously unheard and completely coherent songs or symphonies of any style. | The experience of [[Auditory effects - Psychedelics#Hallucinations|auditory hallucinations]] on MDMA is extremely common, usually occurring at the end of the night, and almost always consisting of memory replays from the previous several hours. They are commonly manifested as spontaneous clips of the music that was played and garbled voices of the people that were spoken too. These can become as loud in volume as the level of noise heard at any rave or house party and can occasionally become complex enough to manifest themselves as intricate, previously unheard and completely coherent songs or symphonies of any style. | ||
==Toxicity and | ==Toxicity and harm potential== | ||
MDA also differs from its methylated cousin MDMA in its acute toxicity—it is clearly more toxic, with toxicity indicative of overstimulation of the central nervous system and the cardiovascular system.<ref>Diaz, Jaime. How Drugs Influence Behavior. Englewood Cliffs: Prentice Hall, 1996.</ref> Symptoms of acute toxicity may include agitation, sweating, increased blood pressure and heart rate, dramatic increase in body temperature, convulsions, and death. Death is usually caused by cardiac effects and subsequent hemorrhaging in the brain (stroke).<ref>Diaz, Jaime. How Drugs Influence Behavior. Englewood Cliffs: Prentice Hall, 1996.</ref> The website erowid.org lists the fatality rate at roughly 2 in 100,000 users, assuming it has similar rates as MDMA.<ref>http://www.erowid.org/chemicals/mda/mda_effects.shtml</ref> | MDA also differs from its methylated cousin MDMA in its acute toxicity—it is clearly more toxic, with toxicity indicative of overstimulation of the central nervous system and the cardiovascular system.<ref>Diaz, Jaime. How Drugs Influence Behavior. Englewood Cliffs: Prentice Hall, 1996.</ref> Symptoms of acute toxicity may include agitation, sweating, increased blood pressure and heart rate, dramatic increase in body temperature, convulsions, and death. Death is usually caused by cardiac effects and subsequent hemorrhaging in the brain (stroke).<ref>Diaz, Jaime. How Drugs Influence Behavior. Englewood Cliffs: Prentice Hall, 1996.</ref> The website erowid.org lists the fatality rate at roughly 2 in 100,000 users, assuming it has similar rates as MDMA.<ref>http://www.erowid.org/chemicals/mda/mda_effects.shtml</ref> | ||
===Interactions=== | ===Interactions=== | ||
MDMA should not be taken alongside any SSRI, [[RIMA]] or [[MAOI]] drugs, due to the risk of [[serotonin syndrome]]. | MDMA should not be taken alongside any SSRI, [[RIMA]] or [[MAOI]] drugs, due to the risk of [[serotonin syndrome]]. | ||
===Lethal | ===Lethal dosage=== | ||
The median lethal dose (LD50) in mice has been reported as 92 mg/kg by intraperitoneal injection. This puts the estimated fatal dosage for a 60kg human being at 5520mg although it should be noted that toxic side effects can be triggered well below this amount. | The median lethal dose (LD50) in mice has been reported as 92 mg/kg by intraperitoneal injection. This puts the estimated fatal dosage for a 60kg human being at 5520mg although it should be noted that toxic side effects can be triggered well below this amount. | ||
===Tolerance and | ===Tolerance and addiction potential=== | ||
MDA usage forms a tolerance. MDA can be taken multiple days in a row, but a higher dosage will need to be administered each consecutive day. Eventually, positive effects will not be noticed as negative side effects increase. MDA has mild psychological addictive potential. | MDA usage forms a tolerance. MDA can be taken multiple days in a row, but a higher dosage will need to be administered each consecutive day. Eventually, positive effects will not be noticed as negative side effects increase. MDA has mild psychological addictive potential. | ||
==Legal | ==Legal issues== | ||
*'''Brazil:''' Possession, production and sale is illegal. | *'''Brazil:''' Possession, production and sale is illegal. | ||
*'''Canada:''' MDA is a Schedule I drug. | *'''Canada:''' MDA is a Schedule I drug. | ||
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*'''USA:''' MDA is a Schedule I drug. | *'''USA:''' MDA is a Schedule I drug. | ||
==See | ==See also== | ||
*[[Psychedelics]] | *[[Psychedelics]] | ||
*[[Entactogens]] | *[[Entactogens]] |