Routes of administration: Revision history

3 June 2025

• curprev 02:5202:52, 3 June 2025 >David Hedlund 35,563 bytes +1,529 Restored https://psychonautwiki.org/w/index.php?title=Routes_of_administration&diff=160897&oldid=160483 (merged back text from Template:Warning/Nasal administration) as the snorting awareness campaign has ended

9 August 2024

• curprev 18:4218:42, 9 August 2024 >Maxipoop 34,034 bytes +708 Added another category and two related routes of administration

7 June 2024

• curprev 21:5621:56, 7 June 2024 >David Hedlund 33,326 bytes +74 →Chasing the dragon: Chasing the dragon, aka foily, can be considered unresponsible drug use due to its unpredictable nature.
• curprev 21:4821:48, 7 June 2024 >David Hedlund 33,252 bytes +286 Improved the flow for =====Chasing the dragon===== ======Risks======
• curprev 21:4321:43, 7 June 2024 >David Hedlund 32,966 bytes +354 copy/paste "Moreover, using specialized smoking devices like bongs designed..." from https://en.wikipedia.org/wiki/Chasing_the_dragon

22 May 2024

• curprev 19:2419:24, 22 May 2024 >David Hedlund 32,612 bytes +228 A rapid rise in concentration can trigger a quick [https://en.wikipedia.org/wiki/Rush_(psychology) rush] of effects for many substances.
• curprev 19:1419:14, 22 May 2024 >David Hedlund 32,384 bytes +570 copy "Intravenous injection is the fastest route of administration, causing blood concentrations to rise the most quickly, followed by smoking, suppository (anal or vaginal insertion), insufflation (snorting), and ingestion (swallowing)." from https://en.wikipedia.org/wiki/Rush_(psychology)
• curprev 19:1119:11, 22 May 2024 >David Hedlund 31,814 bytes +6 Moved =====The Machine===== and =====Chasing the dragon===== under ====Vaporized====
• curprev 19:0919:09, 22 May 2024 >David Hedlund 31,808 bytes +2 move =====Gravity bong===== under ====Smoked====

16 May 2024

• curprev 06:5706:57, 16 May 2024 >David Hedlund 31,806 bytes +45 →Subcutaneous: https://en.wikipedia.org/wiki/Skin_popping

14 May 2024

• curprev 08:4608:46, 14 May 2024 >David Hedlund 31,761 bytes −12 →Gravity bong: thumb|A gravity bong made from a large PET bottle and a bucket.
• curprev 08:4008:40, 14 May 2024 >David Hedlund 31,773 bytes +97 c/p thumb|A "lung" or "parachute bong" with the bag pulled out of the chamber from https://en.wikipedia.org/wiki/Gravity_bong
• curprev 08:3508:35, 14 May 2024 >David Hedlund 31,676 bytes +4 →E-cigarette: indent
• curprev 08:0408:04, 14 May 2024 >David Hedlund 31,672 bytes +220 →Orally inactive tryptamines: Additionally, many alkaloids, have a bitter taste that makes them difficult to keep in the mouth, triggering a swallowing reflex. To improve tolerability with this route, using a safe taste-masking agent is recommended.
• curprev 06:5606:56, 14 May 2024 >David Hedlund 31,452 bytes −28 →Inhalants: Nitrous oxide
• curprev 06:5406:54, 14 May 2024 >David Hedlund 31,480 bytes +219 Inhalants can be delivered through the respiratory system in two main ways: Mouth inhalation, Nasal inhalation
• curprev 06:5006:50, 14 May 2024 >David Hedlund 31,261 bytes +12 Mouth/nasal inhalation
• curprev 06:4806:48, 14 May 2024 >David Hedlund 31,249 bytes 0 sort ====Buccal====
• curprev 06:4806:48, 14 May 2024 >David Hedlund 31,249 bytes +25 Oral mucosa
• curprev 03:3303:33, 14 May 2024 >David Hedlund 31,224 bytes +50 →Spots: thumb|Spotting knives heating
• curprev 03:3203:32, 14 May 2024 >David Hedlund 31,174 bytes +894 Added =====Spots===== -- c/p text from https://en.wikipedia.org/wiki/Spots_(cannabis)
• curprev 03:2703:27, 14 May 2024 >David Hedlund 30,280 bytes +14 m
• curprev 03:2603:26, 14 May 2024 >David Hedlund 30,266 bytes +17 →Orally inactive tryptamines: m
• curprev 03:2503:25, 14 May 2024 >David Hedlund 30,249 bytes +153 ===Orally inactive tryptamines===: In the mouth (buccal (sublabial), sublingual): Holding the substances in the mouth can increase salivation, causing it to be swallowed and deactivated by stomach enzymes.
• curprev 03:2003:20, 14 May 2024 >David Hedlund 30,096 bytes +4 →Transdermal: m
• curprev 03:0203:02, 14 May 2024 >David Hedlund 30,092 bytes +1 →Risks: m
• curprev 02:4602:46, 14 May 2024 >David Hedlund 30,091 bytes −1 →Risks: m

13 May 2024

• curprev 23:2123:21, 13 May 2024 >David Hedlund 30,092 bytes +2 →Multi-route hazard substances: m
• curprev 23:1923:19, 13 May 2024 >David Hedlund 30,090 bytes −51 Multi-route hazard substances
• curprev 23:1923:19, 13 May 2024 >David Hedlund 30,141 bytes +15 Move 25I-NBOMe under ===Oral=== ====Risks====
• curprev 23:1723:17, 13 May 2024 >David Hedlund 30,126 bytes −144 →Safety precautions for certain substances: m
• curprev 23:1623:16, 13 May 2024 >David Hedlund 30,270 bytes +288 c/p "25I-NBOMe is widely rumored to be orally inactive; however, apparent overdoses have occurred via oral administration." from https://en.wikipedia.org/wiki/25I-NBOMe
• curprev 23:1123:11, 13 May 2024 >David Hedlund 29,982 bytes +1 Orally inactive tryptamines
• curprev 23:0923:09, 13 May 2024 >David Hedlund 29,981 bytes −2 m
• curprev 23:0123:01, 13 May 2024 >David Hedlund 29,983 bytes +19 m
• curprev 23:0023:00, 13 May 2024 >David Hedlund 29,964 bytes +217 →Orally inactive substances: it is important to note that MAOIs require careful consideration, as they can be dangerous when combined with certain drug classes, potentially leading to life-threatening consequences if not used properly.
• curprev 22:5622:56, 13 May 2024 >David Hedlund 29,747 bytes +172 ===Orally inactive substances===: * Substances: 5-MeO-DMT, DMT.
• curprev 22:5022:50, 13 May 2024 >David Hedlund 29,575 bytes +530 →DMT: Inconclusive experiences due to swallowed DMT may lead to a false sense of security, potentially causing users to increase the dose in subsequent administrations. However, due to the unpredictable nature of intranasal dripping, this could result in an unexpectedly potent dose due to less DMT being metabolized in the stomach.

11 May 2024

• curprev 21:5521:55, 11 May 2024 >David Hedlund 29,045 bytes +21 wording
• curprev 21:3421:34, 11 May 2024 >David Hedlund 29,024 bytes 0 →DMT: m
• curprev 21:3421:34, 11 May 2024 >David Hedlund 29,024 bytes +124 ==Safety precautions for certain substances== DMT absorbed through the nose may drip down your throat and be swallowed. If swallowed, it will be broken down in your stomach and have no effect.

10 May 2024

• curprev 18:2418:24, 10 May 2024 >David Hedlund 28,900 bytes 0 m
• curprev 18:2218:22, 10 May 2024 >David Hedlund 28,900 bytes −6 Non-oral administration methods circumvent the gastrointestinal tract's breakdown of certain compounds like DMT, which would otherwise necessitate the use of monoamine oxidase inhibitors (MAOIs), referred to as pharmahuasca or ayahuasca when the MAOI and DMT originate from plant extracts, if ingested orally. However, combining MAOIs with many psychoactive substances or tyramine-rich foods can be extremely dangerous.
• curprev 18:0918:09, 10 May 2024 >David Hedlund 28,906 bytes +12 →Transdermal: m
• curprev 18:0918:09, 10 May 2024 >David Hedlund 28,894 bytes +264 →Transdermal: https://en.wikipedia.org/wiki/Nicotine_patch https://en.wikipedia.org/wiki/Caffeine_patch
• curprev 17:5717:57, 10 May 2024 >David Hedlund 28,630 bytes 0 m
• curprev 17:5717:57, 10 May 2024 >David Hedlund 28,630 bytes +206 c/p "Image:SpiRaL.jpg..." and "File:Cocaine lines 2.jpg..." from https://en.wikipedia.org/wiki/Nasal_administration
• curprev 17:5317:53, 10 May 2024 >David Hedlund 28,424 bytes +104 →Buccal: c/p "thumb|right|[[Dipping tobacco is placed directly in the mouth.]]" from https://en.wikipedia.org/wiki/Smokeless_tobacco
• curprev 17:4317:43, 10 May 2024 >David Hedlund 28,320 bytes +112 →Injection: Injecting a substance also bypasses the GI tract's tendency to break certain substances down, such as DMT.
• curprev 17:4217:42, 10 May 2024 >David Hedlund 28,208 bytes +110 Boofing a substance also bypasses the GI tract's tendency to break certain substances down, such as DMT.