Gabapentin: Revision history

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31 January 2025

30 January 2025

19 November 2024

21 April 2024

16 April 2024

21 December 2023

  • curprev 15:3615:36, 21 December 2023 >SkinwalkerSchizo m 23,076 bytes +1 Added one comma after "...certain calcium channels in the brain..."; small grammatical improvement

9 November 2022

27 July 2022

12 November 2021

11 November 2021

5 November 2021

1 November 2021

  • curprev 22:4222:42, 1 November 2021 >Utaninja 18,940 bytes +497 Added another study that tested the theory of the previously mentioned FDA study on suicide risk for gabapentin and also added a note from that study that showed that the studies are most likely inaccurate to a degree.

16 September 2021

  • curprev 20:4920:49, 16 September 2021 >Gabagaba 18,443 bytes −344 This line references a study on "gabapentin enacarbil", which is not the same as gabapentin.

11 May 2021

  • curprev 03:4703:47, 11 May 2021 >Rosie m 18,787 bytes 0 Subjective effects: it previously said its not very good at relieving acute pain, such as opiates which, although isnt hard to get what was meant when read literally is referring to opiates as a type of acute pain, or maybe just that opiates arent good for acute pain. i changed this to reflect what i assume was meant, that it's not effective unlike opiates, which are well known to be effective pain relief.

3 March 2021

  • curprev 22:2522:25, 3 March 2021 >Discount Pharmacologist 18,787 bytes +470 Pharmacological information and citations added
  • curprev 22:2422:24, 3 March 2021 >Discount Pharmacologist 18,317 bytes +1,086 Chemistry info, spelling error correction, and citations

1 January 2021

  • curprev 19:5119:51, 1 January 2021 >DiphenylHydra m 17,231 bytes +54 Added what is very clearly missing info about the bioavailability drop-off of gabapentin—which should have been included when the bioavailability percentage drop-off info was first added to the pharmacology section since it is information found in the end of the sentence which was paraphrased from page 3, 1st paragraph of this reference: http://www.accessdata.fda.gov/drugsatfda_docs/nda/2002/21-397.pdf_Neurontin_BioPharmr.pdf

3 December 2020

30 November 2020

  • curprev 15:0815:08, 30 November 2020 >Petergazer666 m 17,177 bytes +374 Added another NCBI source confirming that Gabapentin is able to increase GABA concentrations in vivo.

20 November 2020

9 July 2020

13 January 2020

26 November 2019

5 November 2019

1 November 2019

10 October 2019

23 July 2019

29 May 2019

17 May 2019

3 May 2019

30 April 2019

20 April 2019

  • curprev 22:0122:01, 20 April 2019 >Tracer m 14,225 bytes +249 *[https://isomerdesign.com/PiHKAL/explore.php?id=8697 Gabapentin (TiHKAL / Isomer Design)]

6 April 2019

  • curprev 22:0222:02, 6 April 2019 >Gabapentinoid 13,976 bytes +1,904 Added sources, information on hydrophilicity and lipophilicity of Gabapentin, dosage-dependent bioavailability, pH dependent absorption, gabapentin transporter saturation and its causes, slight adjustments to phrasing of tolerance's effects on euphoria.
  • curprev 20:5420:54, 6 April 2019 >Gabapentinoid m 12,072 bytes +24 Linked the word "anxiolytic" to https://psychonautwiki.org/wiki/Anxiety_suppression
  • curprev 19:2519:25, 6 April 2019 >Gabapentinoid m 12,048 bytes +147 Altered and clarified description of pharmacological effects on GABA biosynthesis and Voltage-Gated Calcium Channels.

23 March 2019

9 July 2018

7 July 2018

27 June 2018

  • curprev 22:1522:15, 27 June 2018 >Unity 11,540 bytes −39 Gabapentin is not known to cause compulsive redosing unlike other GABAergics such as GHB or alprazolam. Cases of addiction have been documented, however.
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